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Books > Medicine > Pre-clinical medicine: basic sciences

Melanoma Development - Molecular Biology, Genetics and Clinical Application (Hardcover, 2nd ed. 2017): Anja K Bosserhoff Melanoma Development - Molecular Biology, Genetics and Clinical Application (Hardcover, 2nd ed. 2017)
Anja K Bosserhoff
R6,407 Discovery Miles 64 070 Ships in 12 - 17 working days

This book focuses on malignant melanoma, discussing the current state of scientific knowledge and providing insights into the underlying basic mechanisms, the molecular changes, genetics and genomics. Human Melanoma is a dangerous type of skin cancer affecting an increasing population, and a better understanding of its development will help in finding sophisticated targeted therapies. The second revised edition features the latest research findings and offers updates on the latest advances and potential novel melanoma therapies. It is a valuable resource for researchers and clinicians working in the fields of melanoma, cancer research and therapy as well as dermatology.

Ageless - The New Science of Getting Older Without Getting Old (Paperback): Andrew Steele Ageless - The New Science of Getting Older Without Getting Old (Paperback)
Andrew Steele
R338 R276 Discovery Miles 2 760 Save R62 (18%) Ships in 9 - 15 working days

'A stunner ... If you haven't got this book in your house, I don't know why' Chris Evans 'A startling wake-up call . . . Writing with the vim of a Bill Bryson and the technical knowledge of a scientist, Steele gives us a chance to grasp what's at stake' Independent 'An exhilarating journey . . . Steele is a superb guide' Telegraph 'A fascinating read with almost every page bursting with extraordinary facts . . . Read it now' Mail on Sunday Ageless is a guide to the biggest issue we all face. Ageing - not cancer, not heart disease - is the world's leading cause of death and suffering. What would the world be like if we could cure it? Living disease-free until the age of 100 is achievable within our lifetimes. In prose that is lucid and full of fascinating facts, Ageless introduces us to the cutting-edge research that is paving the way for this revolution. Computational biologist Andrew Steele explains what occurs biologically as we age, as well as practical ways we can slow down the process. He reveals how understanding the scientific implications of ageing could lead to the greatest discovery in the history of civilisation - one that has the potential to improve billions of lives, save trillions of dollars, and transform the human condition.

Herbal Bioactive-Based Drug Delivery Systems - Challenges and Opportunities (Paperback): Inderbir Singh Bakshi, Rajni Bala,... Herbal Bioactive-Based Drug Delivery Systems - Challenges and Opportunities (Paperback)
Inderbir Singh Bakshi, Rajni Bala, Reecha Madaan, Rakesh K. Sindhu
R4,100 Discovery Miles 41 000 Ships in 12 - 17 working days

Herbal Bioactive-Based Drug Delivery Systems: Challenges and Opportunities provides a wide-ranging, in-depth resource for herbal bioactives, including detailed discussion of standardization and regulations. The book first explores specific drug delivery systems such as gastrointestinal, ocular, pulmonary, transdermal, and vaginal and rectal. It then discusses novel applications for nano, cosmetics, nutraceuticals, wound healing and cancer treatment. Finally, there is a section focusing on standardization and regulation which includes an enhancement of properties. This book is an essential resource for pharmacologists, pharmaceutical scientists, material scientists, botanists, and all those interested in natural products and drug delivery systems developments.

Enhancing Fertility through Functional Medicine - Using Nutrigenomics to Solve 'Unexplained' Infertility (Paperback):... Enhancing Fertility through Functional Medicine - Using Nutrigenomics to Solve 'Unexplained' Infertility (Paperback)
Jaclyn Downs
R1,210 Discovery Miles 12 100 Ships in 9 - 15 working days

Enhancing Fertility through Functional Medicine: Using Nutrigenomics to Solve 'Unexplained' Infertility provides cutting-edge information and solutions to help support the worldwide rise of fertility challenges. It addresses common, yet not commonly known, root-causes of oxidative stress that are at the heart of reproductive issues (and all chronic health issues). These solutions can help enhance the outcomes of Assisted Reproductive Technologies (ART) or support women to avoid them altogether. Enhancing Fertility through Functional Medicine: Using Nutrigenomics to Solve 'Unexplained' Infertility will show you how to improve cell health (including egg and sperm), lower inflammation, balance nervous system functioning, and optimize genetic expression, allowing the body to return to its naturally fertile state. It details information on numerous root causes of health-derailing inflammation and oxidative stress, while the appendices discuss the genetic and biochemical pathways related to these topics. Each chapter also provides easy "Action Steps" that can be implemented immediately. Chapter topics include iron dysregulation; oxalates; mold/mycotoxins; phase 2 liver detoxification pathways; fat utilization; introductory information on genetics, epigenetics, and nutrigenomics; everything one needs to know about histamine intolerance; and how these factors adversely affect metabolic and reproductive functions. Enhancing Fertility through Functional Medicine: Using Nutrigenomics to Solve 'Unexplained' Infertility is the handbook for people wanting to achieve and sustain a healthy pregnancy. It highlights lesser-known causes of fertility challenges the reader can learn how to investigate. This book also serves as a reference guide for practitioners, providing them with additional tools to add to their repertoires when other protocols have not been effective. It may also provide clarity as to why other protocols did not work, and will enable the practitioner to custom-tailor protocols for each patient.

Carbohydrate Chemistry - Proven Synthetic Methods, Volume 5 (Paperback): Paul Kosma, Tanja M. Wrodnigg, Arnold Stutz Carbohydrate Chemistry - Proven Synthetic Methods, Volume 5 (Paperback)
Paul Kosma, Tanja M. Wrodnigg, Arnold Stutz
R2,024 Discovery Miles 20 240 Ships in 9 - 15 working days

Volumes in the Proven Synthetic Methods Series address the concerns many chemists have regarding irreproducibility of synthetic protocols, lack of identification and characterization data for new compounds, and inflated yields reported in chemical communications-trends that have recently become a serious problem. Exploring carbohydrate chemistry from both the academic and industrial points of view, this unique resource brings together useful information into one convenient reference. The series is unique among other synthetic literature in the carbohydrate field in that, to ensure reproducibility, an independent checker has verified the experimental parts involved by repeating the protocols or using the methods. Featuring contributions from world-renowned experts and overseen by a highly respected series editor, this latest volume compiles reliable protocols for the preparation of intermediates for carbohydrate synthesis or other uses in the glycosciences. Key Features: Explains reliable and tested protocols for the preparation of intermediates for carbohydrate synthesis Offers a unique resource in glycosciences, compiling useful information in one reference Presents protocols that are of wide use to a broad range of readers in the carbohydrate field and the life sciences, including undergraduates taking carbohydrate workshops Explores synthetic carbohydrate chemistry from both the academic and industrial points of view Guarantees the reader a good, clean, reproducible experiment

Regenerative Medicine - from Protocol to Patient - 1. Biology of Tissue Regeneration (Hardcover, 3rd ed. 2016): Gustav Steinhoff Regenerative Medicine - from Protocol to Patient - 1. Biology of Tissue Regeneration (Hardcover, 3rd ed. 2016)
Gustav Steinhoff
R2,981 Discovery Miles 29 810 Ships in 10 - 15 working days

Regenerative medicine is the main field of groundbreaking medical development and therapy using knowledge from developmental and stem cell biology, as well as advanced molecular and cellular techniques. This collection of volumes on Regenerative Medicine: From Protocol to Patient, aims to explain the scientific knowledge and emerging technology, as well as the clinical application in different organ systems and diseases. International leading experts from all over the world describe the latest scientific and clinical knowledge of the field of regenerative medicine. The process of translating science of laboratory protocols into therapies is explained in sections on regulatory, ethical and industrial issues. This collection is organized into five volumes: (1) Biology of Tissue Regeneration, (2) Stem Cell Science and Technology, (3) Tissue Engineering, Biomaterials and Nanotechnology, (4) Regenerative Therapies I, and (5) Regenerative Therapies II. The textbook gives the student, the researcher, the health care professional, the physician and the patient a complete survey on the current scientific basis, therapeutical protocols, clinical translation and practiced therapies in regenerative medicine. Volume 1 contains eleven chapters addressing the latest basic science knowledge on the "Biology of Tissue Regeneration". The principles of cell regeneration control by extracellular matrix and the biology of stem cell niches are explained. Depicted are the principles of molecular mechanisms controlling asymmetric cell division, stem cell differentiation, developmental and regenerative biology, epigenetic and genetic control as well as mathematical modelling for cell fate prediction. Regenerative biology of stem cells in the central nervous and cardiovascular systems leading to complex tissue regeneration in the model species axolotl and zebrafish, as well as the impact of immune signalling on nuclear reprogramming are outlined. These up to date accounts gives the readers advanced insights into the biological principles of the regenerative processes in stem cells, tissues and organisms.

Understanding Pathophysiology (Paperback, 7th edition): Sue E. Huether, Kathryn L McCance Understanding Pathophysiology (Paperback, 7th edition)
Sue E. Huether, Kathryn L McCance
R4,526 Discovery Miles 45 260 Ships in 10 - 15 working days

Make difficult pathophysiology concepts come to life! Filled with vibrant illustrations, simplified language, and detailed online content Understanding Pathophysiology, 7th Edition delivers the most accurate information on treatments, manifestations, and mechanisms of disease across the lifespan. This new edition is fully revised and includes coverage of rare diseases and epigenetics to you with a thorough understanding of conditions affecting the human body. Plus, with over 30 new 3D animations on the companion Evolve site, quick check boxes at the end of each chapter, and disease progression algorithms, this text helps you engage with the fundamental knowledge you need to succeed in nursing school and in practice. Student resources include animations, review questions, answers to the Quick Check boxes (featured in the text), chapter summary reviews, and case study with answers for select chapters. Algorithms throughout the text clarify disease progression. Did You Know boxes highlight new developments in biologic research, diagnostic studies, preventive care, treatments, and more. Quick Check boxes tests your retention of important chapter concepts. Risk Factor boxes alert you to important safety considerations associated with specific diseases. Summary Review sections provide fast, efficient review of chapter content. Geriatric Considerations boxes and Pediatric Considerations boxes highlight key considerations for these demographics in relevant chapters. Consistent presentation helps you to better distinguish pathophysiology, clinical manifestations, and evaluation and treatment for each disease. Glossary of approximately 1,000 terms familiarizes you with the most difficult or important terminology related to pathophysiology. NEW! Chapters on Alterations in Immunity and Obesity and Disorders of Nutrition feature the latest coverage of these hot topics. NEW! Additional coverage of rare diseases and epigenetics gives you a comprehensive understanding of conditions and cell growths that affect the human body. NEW! Streamlined content and illustrations ensures content is at an appropriate level for undergraduate students. NEW! More than 1000 illustrations in the text and 30+ new 3D animations on companion Evolve site bring difficult concepts to life for a new perspective on disease processes.

Animal Anomalies - What Abnormal Anatomies Reveal about Normal Development (Paperback): Lewis I. Held Jr Animal Anomalies - What Abnormal Anatomies Reveal about Normal Development (Paperback)
Lewis I. Held Jr
R1,079 R1,019 Discovery Miles 10 190 Save R60 (6%) Ships in 12 - 17 working days

Among the offspring of humans and other animals are occasional individuals that are malformed in whole or in part. The most grossly abnormal of these have been referred to from ancient times as monsters, because their birth was thought to foretell doom; the less severely affected are usually known as anomalies. This volume digs deeply into the cellular and molecular processes of embryonic development that go awry in such exceptional situations. It focuses on the physical mechanisms of how genes instruct cells to build anatomy, as well as the underlying forces of evolution that shaped these mechanisms over eons of geologic time. The narrative is framed in a historical perspective that should help students trying to make sense of these complex subjects. Each chapter is written in the style of a Sherlock Holmes story, starting with the clues and ending with a solution to the mystery.

The Human Brain during the Second Trimester 190– to 210–mm Crown-Rump Lengths - Atlas of Human Central Nervous System... The Human Brain during the Second Trimester 190– to 210–mm Crown-Rump Lengths - Atlas of Human Central Nervous System Development, Volume 10 (Paperback)
Shirley A. Bayer, Joseph Altman
R1,354 Discovery Miles 13 540 Ships in 12 - 17 working days

This tenth of 15 short atlases reimagines the classic 5 volume Atlas of Human Central Nervous System Development. A handy paperback edition focuses on the second trimester of human brain development. Serial sections from specimens between 190mm and 210mm are illustrated and annotated in great detail, together with 3D reconstructions. An introduction and glossary summarize these earliest stages of human CNS development. Key Features • Classic anatomical atlases • Detailed labeling of the earliest phases of prenatal neurological development • Appeals to neuroanatomists, developmental biologists and clinical practitioners. • Persistent relevance - brain development is not going to change

The Human Brain during the Second Trimester 190– to 210–mm Crown-Rump Lengths - Atlas of Human Central Nervous System... The Human Brain during the Second Trimester 190– to 210–mm Crown-Rump Lengths - Atlas of Human Central Nervous System Development, Volume 10 (Hardcover)
Shirley A. Bayer, Joseph Altman
R3,318 Discovery Miles 33 180 Ships in 12 - 17 working days

This tenth of 15 short atlases reimagines the classic 5 volume Atlas of Human Central Nervous System Development. A handy paperback edition focuses on the second trimester of human brain development. Serial sections from specimens between 190mm and 210mm are illustrated and annotated in great detail, together with 3D reconstructions. An introduction and glossary summarize these earliest stages of human CNS development. Key Features • Classic anatomical atlases • Detailed labeling of the earliest phases of prenatal neurological development • Appeals to neuroanatomists, developmental biologists and clinical practitioners. • Persistent relevance - brain development is not going to change

Essentials of Human Anatomy & Physiology, Global Edition (Paperback, 13th edition): Elaine Marieb, Suzanne Keller Essentials of Human Anatomy & Physiology, Global Edition (Paperback, 13th edition)
Elaine Marieb, Suzanne Keller
R2,106 Discovery Miles 21 060 Ships in 9 - 15 working days

A comprehensive textbook that offers the right balance of Anatomy, Physiology, and Clinical coverage. Essentials of Human Anatomy & Physiology, 13th edition, Global edition by Marieb and Keller, is an essential guide in A & P, focusing on the most important topics in the field. Ideal for one-semester Anatomy and Physiology courses, this text combines short, easy-to-read chapters with accessible figures that you can understand and provides the high-quality content necessary to succeed in the course. This latest edition presents new study tools at the end of each chapter and digital resources to help you study more efficiently and remember the necessary details of the concepts introduced, along with an abundance of mnemonic cues to facilitate learning. Key features include: Clear and friendly writing style featuring familiar analogies you can easily memorise. Easy navigation with numbered sections and sub-sections throughout the book. End-of-chapter Summary Outlines helping you organise your studying more efficiently, followed by relevant questions. A Closer Look & Career Features sections covering key points in the book. Personalise your learning experience and improve results with Mastering (R) A&P. Mastering provides access to trusted content using customisable tools, features, and assessments built for today's digital learners. Pearson Mastering (R) A&P is not included. If you would like to purchase both the physical text and MasteringA&P, search for: 9781292401744 Essentials of Human Anatomy & Physiology, Global Edition, 13th Edition with MasteringA&P & eText The bundle consists of: 9781292401942 Essentials of Human Anatomy & Physiology, Global Edition, 13th Edition 9781292401775 Pearson Mastering A&P - Instant Access - for Essentials of Human Anatomy & Physiology, Global Edition, 13th Edition 9781292401782 PearsonA&P with Pearson eText - Instant Access - for Essentials of Human Anatomy & Physiology, Global Edition, 13th Edition This title is a Pearson Global Edition. The Editorial team at Pearson has worked closely with educators around the world to include content, which is especially relevant to students outside the United States.

DNA Replication, Recombination, and Repair - Molecular Mechanisms and Pathology (Hardcover, 1st ed. 2016): Fumio Hanaoka, Kaoru... DNA Replication, Recombination, and Repair - Molecular Mechanisms and Pathology (Hardcover, 1st ed. 2016)
Fumio Hanaoka, Kaoru Sugasawa
R5,787 Discovery Miles 57 870 Ships in 10 - 15 working days

This book is a comprehensive review of the detailed molecular mechanisms of and functional crosstalk among the replication, recombination, and repair of DNA (collectively called the "3Rs") and the related processes, with special consciousness of their biological and clinical consequences. The 3Rs are fundamental molecular mechanisms for organisms to maintain and sometimes intentionally alter genetic information. DNA replication, recombination, and repair, individually, have been important subjects of molecular biology since its emergence, but we have recently become aware that the 3Rs are actually much more intimately related to one another than we used to realize. Furthermore, the 3R research fields have been growing even more interdisciplinary, with better understanding of molecular mechanisms underlying other important processes, such as chromosome structures and functions, cell cycle and checkpoints, transcriptional and epigenetic regulation, and so on. This book comprises 7 parts and 21 chapters: Part 1 (Chapters 1-3), DNA Replication; Part 2 (Chapters 4-6), DNA Recombination; Part 3 (Chapters 7-9), DNA Repair; Part 4 (Chapters 10-13), Genome Instability and Mutagenesis; Part 5 (Chapters 14-15), Chromosome Dynamics and Functions; Part 6 (Chapters 16-18), Cell Cycle and Checkpoints; Part 7 (Chapters 19-21), Interplay with Transcription and Epigenetic Regulation. This volume should attract the great interest of graduate students, postdoctoral fellows, and senior scientists in broad research fields of basic molecular biology, not only the core 3Rs, but also the various related fields (chromosome, cell cycle, transcription, epigenetics, and similar areas). Additionally, researchers in neurological sciences, developmental biology, immunology, evolutionary biology, and many other fields will find this book valuable.

Human Biochemistry (Hardcover, 2nd edition): Gerald Litwack Human Biochemistry (Hardcover, 2nd edition)
Gerald Litwack
R3,708 Discovery Miles 37 080 Ships in 12 - 17 working days

Human Biochemistry, Second Edition provides a comprehensive, pragmatic introduction to biochemistry as it relates to human development and disease. Here, Gerald Litwack, award-wining researcher and longtime teacher, discusses the biochemical aspects of organ systems and tissue, cells, proteins, enzymes, insulins and sugars, lipids, nucleic acids, amino acids, polypeptides, steroids, and vitamins and nutrition, among other topics. Fully updated to address recent advances, the new edition features fresh discussions on hypothalamic releasing hormones, DNA editing with CRISPR, new functions of cellular prions, plant-based diet and nutrition, and much more. Grounded in problem-driven learning, this new edition features clinical case studies, applications, chapter summaries, and review-based questions that translate basic biochemistry into clinical practice, thus empowering active clinicians, students and researchers.

Tinnitus and Stress - An Interdisciplinary Companion for Healthcare Professionals (Hardcover, 1st ed. 2017): Agnieszka J.... Tinnitus and Stress - An Interdisciplinary Companion for Healthcare Professionals (Hardcover, 1st ed. 2017)
Agnieszka J. Szczepek, Birgit Mazurek
R2,660 Discovery Miles 26 600 Ships in 10 - 15 working days

This book provides up-to-date scientific information on the pathways by which psychosocial stress can affect the auditory system and describes current approaches to the management of patients with stress-related tinnitus. The latest evidence is presented on aspects such as the role of stress hormones in auditory function, the effects of allostatic load, circadian sensitivity to auditory trauma, and the association between stress-related biomarkers and tinnitus. The clinically oriented chapters discuss psychometric instruments of value in the tinnitus clinic and present stress-related tinnitus treatment protocols and outcome measures. It is widely acknowledged that the tinnitus percept acts as a stressor. However, it is also now evident that psychosocial stress can play a causative role in tinnitus and that the impact varies according to the level, duration, and quality of the stress. Assessment of the types and levels of stress in tinnitus patients before, during, and after treatment is therefore very important. Healthcare professionals attending tinnitus patients will benefit from the information that this book provides on the relationship between tinnitus and stress and from the practical guidance that it offers.

The Midlife Cyclist - The Road Map for the +40 Rider Who Wants to Train Hard, Ride Fast and Stay Healthy (Paperback): Phil... The Midlife Cyclist - The Road Map for the +40 Rider Who Wants to Train Hard, Ride Fast and Stay Healthy (Paperback)
Phil Cavell
R390 Discovery Miles 3 900 Ships in 12 - 17 working days

'I am blown away by the level of detail Phil Cavell brings to his work.' - Elinor Barker MBE, multiple world champion and Olympic gold medallist 'The Midlife Cyclist is a triumph' - Cycling Plus 'An amazing accomplishment... a simple-to-understand precis of your midlife as a cyclist - you won't want to put it down.' - Phil Liggett, TV cycling commentator 'Phil is eminently qualified to write The Midlife Cyclist. Well, he is certainly old enough.' - Fabian Cancellara, Tour de France rider and two-time Olympic champion Renowned cycling biomechanics pioneer, Phil Cavell, explores the growing trend of middle-aged and older cyclists seeking to achieve high-level performance. Using contributions from leading coaches, ex-professionals and pro-team doctors, he produces the ultimate manifesto for mature riders who want to stay healthy, avoid injury - and maximise their achievement levels. Time's arrow traditionally plots an incremental path into declining strength and speed for all of us. But we are different to every other generation of cyclists in human history. An ever-growing number of us are determined to scale the highest peaks of elite physical fitness into middle-age and beyond. Can the emerging medical and scientific research help us achieve the holy triumvirate of speed and health with age? The Midlife Cyclist offers a gold standard road-map for the mature cyclist who aims to train, perform and even race at the highest possible level.

Problem Solving in Cancer and Fertility (Paperback): Eleni Karapanagiotou, Julia Kopeika, Ruth E Board, Caroline Archer,... Problem Solving in Cancer and Fertility (Paperback)
Eleni Karapanagiotou, Julia Kopeika, Ruth E Board, Caroline Archer, Melanie C. Davies, …
R1,255 Discovery Miles 12 550 Ships in 9 - 15 working days

The treatment of cancer in young women and men is increasingly turning from focusing purely on survival to a recognition of the long-term effects of treatment on subsequent quality of life. In this regard, fertility is a very high priority for patients. This is the first book to explain the latest techniques in fertility preservation. Chapters cover fertility preservation in both women and men, management of cancer in pregnancy, egg donation and surrogacy, hormone replacement options, counselling and ethical issues. A multidisciplinary team of over 60 specialists were involved in this work, with contributions from leading obstetricians, medical oncologists, gynaecological oncologists, urologists and fertility specialists. The book is formally supported by the Association of Cancer Physicians (ACP). This highly patient-centred, readable text will be of value to a wide range of clinicians and physicians, and doctors in training, in their daily work.

Calcium Entry Pathways in Non-excitable Cells (Hardcover, 1st ed. 2016): Juan A. Rosado Calcium Entry Pathways in Non-excitable Cells (Hardcover, 1st ed. 2016)
Juan A. Rosado
R5,707 Discovery Miles 57 070 Ships in 12 - 17 working days

Calcium entry pathways in non-excitable cells presents a concise synthesis of thoughtfully selected topics covering from the different calcium entry mechanisms in non-excitable cells to the cellular microdomains and organelles regulating the calcium entry process. Particular attention is given to the fascinating group of ion channels involved in different calcium entry pathways as well as the emerging role of these channels in human disease. Calcium entry is an essential mechanism for cellular function in non-excitable cells. In general, two main calcium entry pathways exist in non-excitable cells: one pathway, named store-operated calcium entry (SOCE) requires store depletion and the second pathway is regulated by receptor occupation, but independently on calcium store depletion. The search for the molecular components of calcium entry has identified the stromal interaction molecule 1 (STIM1), as the calcium sensor of the intracellular calcium stores, and Orai as well as TRP channels as the calcium-permeable channels located in the plasma membrane. The location, interactions and function of these channels are finely regulated by a number of scaffolding proteins, membrane microdomains and cellular organelles that fine tune the amount of calcium entering the cell. Cutting-edge and user-friendly, this volume presents relevant background information, critical analysis of the current observations and directions for future research. The book is intended for basic scientists specializing in cellular biology or ion transport, as well as for biomedical researchers.

Delay Ageing - Healthy to 100 (Paperback): Colin Rose Delay Ageing - Healthy to 100 (Paperback)
Colin Rose
R465 R409 Discovery Miles 4 090 Save R56 (12%) Ships in 9 - 15 working days
Male Infertility: Understanding, Causes and Treatment (Hardcover, 1st ed. 2017): Rajender Singh, Kiran Singh Male Infertility: Understanding, Causes and Treatment (Hardcover, 1st ed. 2017)
Rajender Singh, Kiran Singh
R6,441 R5,685 Discovery Miles 56 850 Save R756 (12%) Ships in 12 - 17 working days

This book covers the latest research on male infertility. The topics discussed range from understanding the genetic basis of infertility, to its causes and treatment. Since infertility is also of great interest to the general public, the book also includes a detailed description of what infertility is and how one can understand the different types. Given the complex etiology of infertility, the book includes a number of chapters defining the known and probable causes of male infertility. Providing detailed information suitable for patients and clinicians alike, it also features a separate section on treatment, the ultimate goal.

The United Nations Madrid International Plan of Action on Ageing - Global Perspectives (Paperback): Marvin Formosa, Mala Kapur... The United Nations Madrid International Plan of Action on Ageing - Global Perspectives (Paperback)
Marvin Formosa, Mala Kapur Shankardass
R1,125 Discovery Miles 11 250 Ships in 9 - 15 working days

The United Nations Madrid International Plan of Action on Ageing (MIPAA) offers a bold new agenda for handling the issue of ageing in the 21st-century. It focuses on three priority areas: older persons and development; advancing health and well-being into old age; and ensuring enabling and supportive environments. This book brings together global perspectives on the MIPAA and focusses on and assesses the success and failures of governments to implement its recommendations. Despite its pivotal importance in international ageing policy, the MIPAA has been relatively neglected by academics in their writings and studies. This book mitigates this analytical and empirical cavity. Each chapter focuses on one specific geographical region and addresses five key themes: National ageing situation; Twenty years of MIPAA; Ensuring ageing with dignity; Healthy and active ageing in a sustainable world; and Priorities for the future. It presents an overall summary of the findings, future challenges and opportunities related to ageing, recommendations for future actions to be taken, and policy adjustments needed. The authors also present lessons that were learnt from managing the impact of COVID-19 on older people, together with an outlook on the most immediate priorities for the future so that the recommendations in the MIPAA are achieved in post-COVID-19 and sustainable ethical scenarios. An important contribution towards the advancement of ageing policy, the book will be indispensable to students and researchers of gerontology, ageing, and health. It will also be of interest to policy makers, geriatricians, dementia care specialists, social policy makers responsible for ensuring active and healthy ageing, and all public sector departments which have specific responsibilities towards improving the quality of life of older adults.

Gray's Anatomy Puzzle Book (Paperback): Gareth Moore, Gabrielle M Finn Gray's Anatomy Puzzle Book (Paperback)
Gareth Moore, Gabrielle M Finn
R352 Discovery Miles 3 520 Ships in 12 - 17 working days

Think you know your cranium from your clavicle? Tibia from your trachea? Think again... Test your brain, solve riddles and learn about how the body works with this unique puzzle book using illustrations from Gray's Anatomy. Divided into different sections of the body, the Gray's Anatomy Puzzle Book takes the medical reference classic as its starting point for puzzles, riddles and general knowledge questions that will test your wits and challenge your brain. Learn more about the body in an easy and fun way with questions that vary in difficulty, from easy to fiendish, and are suitable for those with little knowledge of the human body, or those in the know who are interested in testing themselves with a new challenge. Puzzle types include: Sudoku Anagrams Crosswords Encoded pairs Missing letters Secret codes Lettermorphosis Follow visual clues and apply logic to reveal fascinating facts from medical history and learn about how our amazing bodies function.

Obstetrics Essentials - A Question-Based Review (Paperback, 1st ed. 2017): Kate C. Arnold, Caroline J. Flint Obstetrics Essentials - A Question-Based Review (Paperback, 1st ed. 2017)
Kate C. Arnold, Caroline J. Flint
R4,187 Discovery Miles 41 870 Ships in 10 - 15 working days

This book is a compact question-based review of the most critical topics an obstetrician will come across in practice. Each chapter includes 10-30 multiple-choice questions designed to test the readers understanding surrounding one obstetric topic. Based on all 45 obstetric based practice bulletins by ACOG, this text is designed to keep practitioners up-to-date with the latest evidence based medicine. Sample topics include: anemia in pregnancy, screening for fetal chromosomal abnormalities, and vaginal birth after previous cesarean delivery. This is an ideal tool for attendings and clerkship directors who frequently test residents and medical students during rounds and in the classroom. This review also proves useful for practicing physicians and physicians-in-training who want to self-evaluate their comprehension and study for board examinations.

Organelle Contact Sites - From Molecular Mechanism to Disease (Hardcover, 1st ed. 2017): Mitsuo Tagaya, Thomas Simmen Organelle Contact Sites - From Molecular Mechanism to Disease (Hardcover, 1st ed. 2017)
Mitsuo Tagaya, Thomas Simmen
R6,252 Discovery Miles 62 520 Ships in 12 - 17 working days

This book provides the first comprehensive coverage of the quickly evolving research field of membrane contact sites (MCS). A total of 16 chapters explain their organization and role and unveil the significance of MCS for various diseases. MCS, the intracellular structures where organellar membranes come in close contact with one another, mediate the exchange of proteins, lipids, and ions. Via these functions, MCS are critical for the survival and the growth of the cell. Owing to that central role in the functioning of cells, MCS dysfunctions lead to important defects of human physiology, influence viral and bacterial infection, and cause disease such as inflammation, type II diabetes, neurodegenerative disorders, and cancer. To approach such a multifaceted topic, this volume assembles a series of chapters dealing with the full array of research about MCS and their respective roles for diseases. Most chapters also introduce the history and the state of the art of MCS research, which will initiate discussion points for the respective types of MCS for years to come. This work will appeal to all cell biologists as well as researchers on diseases that are impacted by MCS dysfunction. Additionally, it will stimulate graduate students and postdocs who will energize, drive, and develop the research field in the near future.

Long Term Safety of Assisted Reproduction (Paperback): Daniela Nogueira, Kenny A. Rodriguez-Wallberg, Arianna D'Angelo Long Term Safety of Assisted Reproduction (Paperback)
Daniela Nogueira, Kenny A. Rodriguez-Wallberg, Arianna D'Angelo
R2,478 Discovery Miles 24 780 Ships in 9 - 15 working days

A much-needed overview of the available information now accumulating to indicate that assisted reproductive technologies are generally safe for both babies and mothers. However, the literature abounds with reports of a higher risk of obstetric and perinatal complications; regarding the long term outcomes for both women and children, the data are still scarce. The chapters summarized in this book review the current knowledge on long term safety of assisted reproduction and indicate the need for continued research to cover the lack of data in some specific patient groups and for recently developed treatments that only have a short period of follow-up.

Lipoxygenases in Inflammation (Hardcover, 1st ed. 2016): Dieter Steinhilber Lipoxygenases in Inflammation (Hardcover, 1st ed. 2016)
Dieter Steinhilber
R4,749 R3,688 Discovery Miles 36 880 Save R1,061 (22%) Ships in 12 - 17 working days

Oxidation of polyunsaturated fatty acids by lipoxygenases leads to a variety of fatty acid metabolites which play important roles in physiology but also in pathophysiology. Data accumulated during the last decade point to the fact that lipoxygenase metabolites are involved in host defence reactions, cardiovascular system and contribute to the development of inflammatory and allergic diseases, cardiovascular disease and cancer. This PIR volume summarizes the physiological and pathophysiological functions of lipoxygenases.

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