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Books > Medicine > Pre-clinical medicine: basic sciences

Netter's Anatomy Coloring Book (Paperback, 3rd edition): John T. Hansen Netter's Anatomy Coloring Book (Paperback, 3rd edition)
John T. Hansen
R648 Discovery Miles 6 480 Ships in 12 - 17 working days

Reinforce your knowledge of structures, pathways, and relationships with this active and engaging review tool! Netter's Anatomy Coloring Book, 3rd Edition is cross-referenced to the bestselling Netter's Atlas of Human Anatomy, 8th Edition, so you know you're benefiting from reliable, up-to-date anatomical information. This comprehensive book is a fun and easy way to trace arteries, veins, and nerves through their courses and bifurcations, reinforce your understanding of muscle origins and insertions, and develop a better understanding of the integration of individual organs in the workings of each body system throughout the human form. Whether you are taking an anatomy course or just curious about how the body works, you'll learn and master anatomy with ease. Netter's Anatomy Coloring Book is a perfect companion to the Atlas of Human Anatomy by Frank H. Netter, MD, as well as Netter's Anatomy Flash Cards and Netter's Clinical Anatomy textbook. Presents each topic in two-page spreads-with outlines of Netter anatomical illustrations for coloring accompanied by high-yield information-that give context to the structures. Features illustrations small enough for quick coloring, but large enough to provide you with important details, as well as multiple views/planes for better understanding of spatial relationships. Offers tips for coloring key structures that emphasize how a coloring exercise can reinforce learning. Contains helpful tables that review muscle attachments, innervation, action, and blood supply. Features expanded Clinical Notes which highlight the importance of anatomy in medicine. Includes Summary Exercises and Review Questions at the end of each system to reinforce learning. Provides online access where you can search the complete contents of the book and view completed coloring pages-done by other students-for reference. Enhanced eBook version included with purchase. Your enhanced eBook allows you to access all of the text, figures, and references from the book on a variety of devices.

Organogenetic Gene Networks - Genetic Control of Organ Formation (Hardcover, 1st ed. 2016): James Castelli-Gair Hombria, Paola... Organogenetic Gene Networks - Genetic Control of Organ Formation (Hardcover, 1st ed. 2016)
James Castelli-Gair Hombria, Paola Bovolenta
R5,564 Discovery Miles 55 640 Ships in 12 - 17 working days
Period Power - Harness Your Hormones and Get Your Cycle Working For You (Paperback): Maisie Hill Period Power - Harness Your Hormones and Get Your Cycle Working For You (Paperback)
Maisie Hill 1
R474 R391 Discovery Miles 3 910 Save R83 (18%) Ships in 9 - 15 working days

'Hill's advice is straightforward and no-nonsense' - The Guardian 'A life-transforming book... fascinating - Daily Mail 'Maisie Hill has written a bloody brilliant book (pun intended). Everything you need to know about periods and how they affect you and your life is here. It's revolutionary' - Miranda Sawyer 'Thank GOODNESS for Maisie Hill! Flipping open the lid on a vital conversation. It's about time we claimed the power of our periods!' - Gemma Cairney, broadcaster & co-founder of Boom Shakalaka Productions 'This is such an important book. Maisie's insights and cycle strategy have changed my life and my cycle. Period Power is written with such intelligence, humour and a deep understanding of women's health. If you have a period you need to read this book.' - Anna Jones, author of The Modern Cook's Year A profound and practical blueprint for aligning daily life with your menstrual cycle. Period Power is the handbook to periods and hormones that will leave you wondering why the hell nobody told you this sooner. The hormones of the menstrual cycle profoundly influence our energy, mood and behaviour, but all too often we're taught that our hormones make us unreliable, moody bitches, or that it's our lot in life to put up with 'women's problems'. Maisie Hill, a women's health practitioner, knows the power of working with the menstrual cycle and refuses to accept this theory. Instead, Maisie believes that our hormones are there to serve us and, if utilized correctly, can be used to help you get what you want out of life. Yes, we are hormonal, and that's a very good thing. This revolutionary book reveals everything you need to know about taking control of your menstrual cycle and outlines The Cycle Strategy to help us perform at our best, throughout our cycle. In Period Power you will discover how to: - maximise your natural superpowers each month while making adjustments for the darker days, and use Maisie's favourite tips to improve them - identify your personal patterns, powers and pitfalls for each phase of the menstrual cycle - plan your month to perform at your best in all aspects of your life - figure out if you have a hormonal imbalance and what to do about it. Period Power is a no-nonsense guide with all the tools you need to improve your menstrual health.

ISE Manual of Structural Kinesiology (Paperback, 22nd edition): R.T. Floyd, Clem Thompson ISE Manual of Structural Kinesiology (Paperback, 22nd edition)
R.T. Floyd, Clem Thompson
R1,743 Discovery Miles 17 430 Ships in 12 - 17 working days

Manual of Structural Kinesiology, 22e provides a straightforward view of human anatomy and its relation to movement. While the manual is designed for use in undergraduate structural kinesiology courses, other clinicians and educators will also benefit from the text. The manual clearly identifies specific muscles and muscle groups and describes exercises for strengthening and developing those muscles. The author's goal continues to be to provide important information in an accessible format through a combination of logical presentation, extensive and clear illustrations, and concise writing style.

The Role of Pendrin in Health and Disease - Molecular and Functional Aspects of the SLC26A4 Anion Exchanger (Hardcover, 1st ed.... The Role of Pendrin in Health and Disease - Molecular and Functional Aspects of the SLC26A4 Anion Exchanger (Hardcover, 1st ed. 2017)
Silvia Dossena, Markus Paulmichl
R5,273 Discovery Miles 52 730 Ships in 10 - 15 working days

This book reviews the current state of knowledge on the genetics, molecular biology and physiology of pendrin, with a particular focus on pendrin dysfunction and the consequences for human health. Pendrin is a membrane transport protein expressed in the thyroid, inner ear, kidney and airways, and was recently found in a variety of other tissues and organs. Pendrin malfunction may cause a genetic disease called Pendred syndrome or non-syndromic deafness. The book provides a thorough description of the multifaceted role of pendrin in human health and disease. As such, it offers an invaluable tool for physiology and pathology researchers, while also providing essential guidance for otorhinolaryngologists and endocrinologists in the diagnosis of Pendred syndrome and pendrin-related deafness.

The Liver in Systemic Diseases (Hardcover, 1st ed. 2016): Hiromasa Ohira The Liver in Systemic Diseases (Hardcover, 1st ed. 2016)
Hiromasa Ohira
R5,512 Discovery Miles 55 120 Ships in 12 - 17 working days

Based on the results of studies on autoimmunity, the endocrine system, nutrients, metal metabolism and intestinal bacterial flora, this volume thoroughly covers studies on functional correlation of the liver with the spleen, visceral fat, intestinal tract, and central nervous system. Including associations with dysbiosis, nonalcoholic steatohepatitis (NASH) and hepatocellular carcinoma, it offers comprehensive data on correlations of organs with the liver from basic and clinical viewpoints. The Liver in Systemic Diseases will especially be of interest to researchers, clinical residents and medical students with an interest in hepatology and gastroenterology. Furthermore, the book has interdisciplinary appeal and provides a foundation that will help physicians to consider clinical conditions of diseases from a broader perspective.

Multidirectional Speed in Sport - Research to Application (Paperback): Paul Jones, Thomas Dos'Santos Multidirectional Speed in Sport - Research to Application (Paperback)
Paul Jones, Thomas Dos'Santos
R1,174 Discovery Miles 11 740 Ships in 9 - 15 working days

During field and court-based sports, players are continually required to perceive their environment within a match and select and perform the most appropriate action to achieve their immediate goal within that match instance. This ability is commonly known as agility, considered a vital quality in such sports and may incorporate a variety of locomotion and instantaneous actions. Multidirectional speed is a global term to describe the competency and capacity to perform such actions, to accelerate, decelerate, change direction and ultimately maintain speed in multiple directions and movements within the context of sports specific scenarios, encompassing many of these agility, speed, and related qualities. Multidirectional speed in sport depends on a multitude of factors including perceptual-cognitive abilities, physical qualities, and the technical ability to perform the abovementioned actions. Multidirectional Speed in Sport: Research to Application reviews the science of multidirectional speed and translates this information into real-world application in order to provide a resource for practitioners to develop multidirectional speed with athletes, bringing together knowledge from a wealth of world-leading researchers and applied practitioners in the area of 'speed and agility' to provide a complete resource to assist practitioners in designing effective multidirectional speed development programmes. This text is critical reading for undergraduate and graduate sports science students, all individuals involved in training athletes (e.g., coaches, physiotherapists, athletic trainers) along with researchers in the field of sports science and sports medicine.

Still Distracted After All These Years - Help and Support for Older Adults with ADHD (Paperback): Kathleen Nadeau Still Distracted After All These Years - Help and Support for Older Adults with ADHD (Paperback)
Kathleen Nadeau
R472 R389 Discovery Miles 3 890 Save R83 (18%) Ships in 9 - 15 working days

The world's foremost expert shares advice on later-in-life ADHD, tackling everything from finances, parenting, planning for retirement, social life and work, in this practical and helpful guide for those with and without a diagnosis. Do you... · Forget to pay bills? · Live in a disorganised environment? · Struggle with mental health? · Procrastinate on projects, even ones that initially excite you? · Have high levels of conflict with those close to you? · Have a child diagnosed with ADHD and/or a family history of learning disorders? If some of these patterns sound familiar, you might understandably fear the onset of dementia, but you may have undiagnosed attention deficit hyperactivity disorder (ADHD). ADHD in adults is one of the most common disorders. Living with ADHD in our later years is hugely influenced by co-occurring issues, such as anxiety, depression or low self-esteem. In addition, the presence of learning disorders, heightened levels of stress, the presence or lack of support from others, and the number of people we are responsible for, can all complicate and intensify the effects of ADHD. The good news is that you've come to the right place to learn more about how to lead a calmer, happier, more productive life. Dedicated to the health and wellbeing of today's older adults with ADHD, Still Distracted After All These Years offers strategies to build a support system, gain better control over your daily life and create a more ADHD-friendly retirement.

Cardiomyocytes - Active Players in Cardiac Disease (Hardcover, 1st ed. 2016): Klaus-Dieter Schluter Cardiomyocytes - Active Players in Cardiac Disease (Hardcover, 1st ed. 2016)
Klaus-Dieter Schluter
R5,374 Discovery Miles 53 740 Ships in 12 - 17 working days

This book summarizes our current understanding about the biology and patho-biology of cardiomyocytes and depicts common techniques for the study of these cells. The book is divided into two parts; the first part provides insight into role and function of cardiomyocytes under normal conditions and describes embryogenesis and differentiation, in the second part the role of cardiomyocytes in aging and disease is discussed and cellular responses under stress conditions illustrated. Cardiomyocytes represent the main mass of the heart, and cellular malfunction directly modifies heart function leading to subsequent heart failure. As such, cardiomyocytes are causative involved in the main reasons of heart failure, such as post-infarct remodeling, hypertensive heart disease, idiopathic heart failure, and interactions with other co-morbidities such as diabetes. On the other hand, cardiomyocytes are necessarily target of therapy. Therefore, a precise understanding of cardiomyocytes biology is a pre-requisite for proper disease treatment and evidence based medicine. The book is written for cell biologists, pharmacologists and biomedical researchers specialized in cardiac and vascular biology.

Comparative Medicine - Disorders Linking Humans with Their Animals (Hardcover, 1st ed. 2017): Erika Jensen-Jarolim Comparative Medicine - Disorders Linking Humans with Their Animals (Hardcover, 1st ed. 2017)
Erika Jensen-Jarolim
R5,003 Discovery Miles 50 030 Ships in 12 - 17 working days

This book highlights the most significant diseases for humans and their dogs, cats and horses. The examples discussed, which include allergies, osteoporosis, cancer and many more, illustrate that humans and their companion animals may in fact develop similar diseases. The reader - whether expert or interested lay - can thus directly compare between human and animal patients. The animal patient thereby represents a natural disease model, which besides the experimental models, is urgently needed to improve the therapeutic options for both humans and animals.

Metallomics - Recent Analytical Techniques and Applications (Hardcover, 1st ed. 2017): Yasumitsu Ogra, Takafumi Hirata Metallomics - Recent Analytical Techniques and Applications (Hardcover, 1st ed. 2017)
Yasumitsu Ogra, Takafumi Hirata
R6,336 Discovery Miles 63 360 Ships in 12 - 17 working days

This book focuses on recent topics in metallomics, a study of the metallome, or metal-containing biomolecules. Metals can induce various physiological and toxicological effects in a very small amounts, in other words, the concentrations of biometals are very low in organisms. Thus, analytical techniques for a trace amount of metal are crucial to understand the biological and toxicological functions of metals.This volume begins with an overview of metallomics including the history and development of the field. Subsequent parts provide basic and advanced techniques for metallomics. Speciation and imaging of metals are basic approaches to reveal the function of the metallome. The applications of speciation using an HPLC hyphenated with inductively coupled plasma mass spectrometry (LC-ICP-MS) and flow cytometry ICP-MS are described. As advanced approaches, the applications using a micro-flow injection-ICP-MS, an ICP-triple quadrupole mass spectrometer, an ICP-sector field mass spectrometer, and an ICP-multi-collector mass spectrometer are mentioned. For the imaging of metals, basic principles and applications of several techniques such as scanning X-ray fluorescence microscopy and ICP-MS equipped with laser ablation (LA-ICP-MS) are presented. Speciation analyses using electrospray ionization mass spectrometry (ESI-MS), X-ray Absorption Spectroscopy (XAS), and nuclear magnetic resonance spectroscopy (NMR) are also introduced. The last part highlights the medical and pharmaceutical applications of metallomics. Molecular biological approaches to reveal the effects of toxic metals, metal functions in brain and neurodegenerative diseases, and metallodrugs are explained. The topic of metal transporters is also presented.

Gonadal Tissue Cryopreservation in Fertility Preservation (Hardcover, 1st ed. 2016): Nao Suzuki, Jacques Donnez Gonadal Tissue Cryopreservation in Fertility Preservation (Hardcover, 1st ed. 2016)
Nao Suzuki, Jacques Donnez
R4,384 R3,586 Discovery Miles 35 860 Save R798 (18%) Ships in 12 - 17 working days

This book is a practical guide to the cryopreservation and transplantation of oocytes, embryos, and ovarian and testicular tissue for fertility preservation. Illustrated with a wealth of figures and photos, it provides updated techniques for clinicians, technicians, and researchers. This book also gives insights into in vitro activation (IVA), in vitro growing (IVG), and in vitro maturation (IVM), with both basic research and future directions. These techniques combined with cryopreservation will improve the chances of reproduction. Cryopreservation is essential to protect fertility in cancer patients who undergo treatment with radioiodine or chemotherapy, which may cause damage to their reproductive organs, and also for primary ovarian insufficiency patients. The book also includes a chapter on the risk of the presence of malignant cells in ovarian tissue. Both editors are pioneering researchers in this field.

Chromosome Structure and Aberrations (Hardcover, 1st ed. 2017): Tariq Ahmad Bhat, Aijaz Ahmad Wani Chromosome Structure and Aberrations (Hardcover, 1st ed. 2017)
Tariq Ahmad Bhat, Aijaz Ahmad Wani
R4,471 Discovery Miles 44 710 Ships in 10 - 15 working days

This book is a compilation of various chapters contributed by a group of leading researchers from different countries and covering up to date information based on published reports and personal experience of authors in the field of cytogenetics. Beginning with the introduction of chromosome, the subsequent chapters on organization of genetic material, karyotype evolution, structural and numerical variations in chromosomes, B-chromosomes and chromosomal aberrations provide an in-depth knowledge and easy understanding of the subject matter. A special feature of the book is the inclusion of a series of chapters on various types of chromosomal aberrations and their impact on breeding behaviour and crop improvement. The possible mechanism, their consequences and role in genetic analysis has been emphasized in these chapters. A few chapters have also been dedicated on various techniques routinely used in the laboratory by students and researchers. Each chapter ends with an extensive bibliography so that the students and researchers may find it relevant to consult more literature on the subject than a book of this size can offer. The book is intended to fulfill the needs of undergraduate and post graduate students of botany, zoology and agriculture besides, teachers and researchers engaged in the field of genetics, cytogenetics, and molecular genetics. In general the readers will find each chapter of the book informative and easy to understand.

Modern Topics in the Phototrophic Prokaryotes - Metabolism, Bioenergetics, and Omics (Hardcover, 1st ed. 2017): Patrick C.... Modern Topics in the Phototrophic Prokaryotes - Metabolism, Bioenergetics, and Omics (Hardcover, 1st ed. 2017)
Patrick C. Hallenbeck
R5,540 Discovery Miles 55 400 Ships in 12 - 17 working days

This book offers authoritative contributions by world experts actively working on different aspects of phototrophic prokaryotes. Providing up-to-date information in this rapidly advancing field, it covers the range of topics that are currently the focus of research with this group of organisms. As essentially single-celled organisms, phototrophic prokaryotes process many environmental signals and use this information to optimize their metabolism, growth rate, DNA replication and cell division. Phototrophic prokaryotes are collectively of great interest for a number of different fundamental and applied perspectives and have long served as models for understanding such basic fundamental biological processes as photosynthesis and respiration. On an ecological/environmental level they are extremely important, being the most abundant photosynthetic organisms on earth and responsible for the majority of the primary productivity in the oceans. They also hold great promise as biotechnological catalysts, being able to couple solar energy conversion through photosynthesis and carbon fixation to the production of biofuels, commodity chemicals and nutraceuticals. The book is recommended to advanced students and scientists dealing with life sciences, especially in genetics, microbiology and molecular biology.

Regenerative Medicine - from Protocol to Patient - 4. Regenerative Therapies I (Hardcover, 3rd ed. 2016): Gustav Steinhoff Regenerative Medicine - from Protocol to Patient - 4. Regenerative Therapies I (Hardcover, 3rd ed. 2016)
Gustav Steinhoff
R3,894 Discovery Miles 38 940 Ships in 12 - 17 working days

Regenerative medicine is the main field of groundbreaking medical development and therapy using knowledge from developmental and stem cell biology as well as advanced molecular and cellular techniques. This collection of volumes on Regenerative Medicine: From Protocol to Patient, aims to explain the scientific knowledge and emerging technology as well as the clinical application in different organ systems and diseases. International leading experts from all over the world describe the latest scientific and clinical knowledge of the field of regenerative medicine. The process of translating science of laboratory protocols into therapies is explained in sections on regulatory, ethical and industrial issues. This collection is organized into five volumes: (1) Biology of Tissue Regeneration, (2) Stem Cell Science and Technology, (3) Tissue Engineering, Biomaterials and Nanotechnology, (4) Regenerative Therapies I, and (5) Regenerative Therapies II. The textbook gives the student, the researcher, the health care professional, the physician and the patient a complete survey on the current scientific basis, therapeutical protocols, clinical translation and practiced therapies in regenerative medicine. Volume 4 first gives a survey on the historical background of science and development of regenerative therapies. Ethical, preclinical and regulatory issues for the introduction of new regenerative therapies are depicted as the current background for clinical translation. The clinical chapters describe the state of development for medical science, technology application, and clinical translation for the nervous system, head, and respiratory system.

Regenerative Medicine: Laboratory to Clinic (Hardcover, 1st ed. 2017): Asok Mukhopadhyay Regenerative Medicine: Laboratory to Clinic (Hardcover, 1st ed. 2017)
Asok Mukhopadhyay
R7,020 Discovery Miles 70 200 Ships in 12 - 17 working days

This book discusses the two different cellular approaches that are pursued in regenerative medicine: cell therapy and tissue engineering. It examines in detail the therapeutic application of hematopoietic stem cells in marrow regeneration, multi-potent mesenchymal stem cells (MSCs), also referred to as mesenchymal stromal cells. The interest in MSCs can be seen in more than 150 clinical trials, some of which have progressed to Phase III, despite the cells' limited differentiation potential. The book also explores how embryonic stem (ES) cells, being pluripotent in nature, can resolve some of the problems associated with adult stem cells, yet entail other challenges like risks of teratoma formation and immune rejection. A separate chapter deals with the role of noncoding RNAs in neuronal commitment of induced pluripotent stem (iPS) cells. Chapters like "Cord blood banking in India and the global scenario"; "3D bioprinting of tissue" and others will make this book an extremely interesting read for all students, researchers and clinicians working in the area of regenerative medicine/stem cells. The book is broadly divided into two parts, the first of which is devoted to basic information on stem cells, and the second of which addresses potential clinical applications in the areas of hematology, cardiology, orthopedic and immune suppression, etc.

In the FLO - A 28-Day Plan Working with Your Monthly Cycle to Do More and Stress Less (Paperback): Alisa Vitti In the FLO - A 28-Day Plan Working with Your Monthly Cycle to Do More and Stress Less (Paperback)
Alisa Vitti 1
R393 R340 Discovery Miles 3 400 Save R53 (13%) Ships in 12 - 17 working days

How women can improve their productivity, happiness, and physical well-being by keeping their natural cycles in mind and working with them (rather than ignoring them). In the Flo teaches women how to use their 28-day cycle to optimize their life by letting their internal clock and natural rhythms guide time management, diet, fitness, etc. (This is so simple and yet under-utilized it is shocking. It makes perfect sense when you think about it: You have different energy levels at different times of the month, different libido levels, etc. so why not use foresight to plan projects for when you are at your most effective, and understand when you need more emotional connection with others?) There are specific tips on what to eat and how to exercise depending on what phase you are in-and it works. Women are getting promotions, losing weight, and in one case thus far, literally clearing their endometriosis by using the cycle syncing method.

Human iPS Cells in Disease Modelling (Hardcover, 1st ed. 2016): Keiichi Fukuda Human iPS Cells in Disease Modelling (Hardcover, 1st ed. 2016)
Keiichi Fukuda
R2,866 Discovery Miles 28 660 Ships in 10 - 15 working days

Human iPS cells have a great potential to be cell sources for regenerative medicine because of the promise of infinite self-renewal and the capability to differentiate into multiple cell types. This book focuses on another great potential of human iPS cells, which is the establishment of human disease models using patient-specific iPS cells. Human iPS cells can be easily obtained from a patient's somatic cells and provide the entire information on the patient's genome. Accordingly, we can generate disease models for inheritable diseases in cell culture dishes using iPS cells. This is a quite new technique but holds tremendous potential for our increased understanding of pathogenesis, and will then be the basis for novel drug development industries. All the authors are leading researchers in this field and they have reported many kinds of patient-derived iPS cells. In this book, they introduce the aspects that could be recapitulated in terms of disease modelling as well as further innovative findings such as novel pathogenetic insights and novel therapies.

Metabolic Engineering for Bioactive Compounds - Strategies and Processes (Hardcover, 1st ed. 2017): Vipin Chandra Kalia, Adesh... Metabolic Engineering for Bioactive Compounds - Strategies and Processes (Hardcover, 1st ed. 2017)
Vipin Chandra Kalia, Adesh Kumar Saini
R5,552 Discovery Miles 55 520 Ships in 12 - 17 working days

This book comprehensively discusses the latest research in the area of metabolic engineering. Metabolic engineering solutions for bioactive compounds are now being derived by means of heterologous gene expression, in a wide range of organisms. The book provides an overview of the model systems being employed for metabolic manipulation to yield bioactive molecules, such as single-cell proteins, antibody generation, metabolites, proteases, chaperones, therapeutic proteins, nanomaterials, polymeric conjugates, dendrimers and nanoassemblies, Escherichia coli, Agrobacterium, Saccharomyces cerevisiae and cell lines, etc. In addition, it shares insights into the scope of these methods in the areas of prevention, diagnosis and treatment of diseases, e.g. immunotherapy for curing various diseases like cancer, allergies, autoimmune diseases, etc.

Molecular and Cellular Biology of Platelet Formation - Implications in Health and Disease (Hardcover, 1st ed. 2016): Harald... Molecular and Cellular Biology of Platelet Formation - Implications in Health and Disease (Hardcover, 1st ed. 2016)
Harald Schulze, Joseph Italiano
R7,514 Discovery Miles 75 140 Ships in 12 - 17 working days

This book gives a comprehensive insight into platelet biogenesis, platelet signal transduction, involvement of platelets in disease, the use of diverse animal models for platelet research and future perspectives in regard to platelet production and gene therapy. Being written by international experts, the book is a concise state-of-the art work in the field of platelet biogenesis, biology and research. It represents an indispensable tool for research scientists in biomedicine, vascular biology, hematopoiesis and hemostasis and specifically for scientists in platelet research, as well as for clinicians in the field of hematology and transfusion medicine.

Hypertension and Metabolic Cardiovascular Risk Factors (Paperback, 1st ed. 2016): Arrigo F. G. Cicero Hypertension and Metabolic Cardiovascular Risk Factors (Paperback, 1st ed. 2016)
Arrigo F. G. Cicero
R1,702 Discovery Miles 17 020 Ships in 10 - 15 working days

The aim of this guide is to provide clinicians with practical reference for the management of hypertensive patients with other cardiovascular risk factors, which originate from impaired metabolic functions. With the aid of carefully selected, paradigmatic case studies, the physician will find sound advice for the best approach to common but often under-recognized clinical situations, and answers to practical questions that arise when a specific condition is not directly addressed in the guidelines. Question-and-answer sections will help the reader to identify at a glance the most complex steps in the diagnostic and therapeutic process. In a "real world" clinical setting, the hypertensive patient rarely presents with hypertension as the only cardiovascular risk factor, and is more likely to be affected by other metabolic risk factors, such as impairment of lipid metabolism, glucose homeostasis, and purine metabolism, and by overweight or obesity. These cases will serve as a basis for analyzing best practice, highlighting problems in diagnosis and treatment, and selecting the most appropriate management of patients with metabolic risk factors in everyday practice.

Bile Acids in Gastroenterology - Basic and Clinical (Hardcover, 1st ed. 2017): Susumu Tazuma, Hajime Takikawa Bile Acids in Gastroenterology - Basic and Clinical (Hardcover, 1st ed. 2017)
Susumu Tazuma, Hajime Takikawa
R5,010 Discovery Miles 50 100 Ships in 12 - 17 working days

This book examines the biological aspects of bile acid analysis and their clinical applications, providing readers with an overview of cutting-edge discussions on Bile Acid research and diseases. It begins with detailed discussions on the biological aspects of bile acid, with chapters examining bile acid from various perspectives, from its metabolism to its use in therapeutic agents. Subsequent chapters focus on diseases involving bile acid abnormalities, and specific applications are addressed concerning gallstones, cholestatic liver disease, NAFLD/NASH, hepatitis, pancreatitis, esophageal cancer and colon cancer. In keeping with the book's integrated approach, the Editor has gathered a broad range of eminent scholars and practitioners to provide a comprehensive review of modern bile acid research. The book offers clinical physicians, basic researchers and postgraduate students essential insights into cutting-edge research and paves the way for further research.

Hepatic De Novo Lipogenesis and Regulation of Metabolism (Hardcover, 1st ed. 2016): James M Ntambi Hepatic De Novo Lipogenesis and Regulation of Metabolism (Hardcover, 1st ed. 2016)
James M Ntambi
R5,459 Discovery Miles 54 590 Ships in 12 - 17 working days

The liver is the largest solid vital organ in mammals that supports other organ in the body in some facet. This book synthesizes all the primary and relevant metabolic information that one needs to review to understand the complex and diverse role of the liver in metabolism. With the current epidemic of metabolic diseases, it is of immediate importance to understand the contribution of the liver in health and its role in the development of impaired metabolic regulation. This book covers the many studies that have unmasked important roles that proteins expressed in the liver play in the development of or protection from metabolic diseases. One of the major metabolic functions of the liver is to carry out de novo lipogenesis, which is the metabolic pathway that allows the conversion of excess carbohydrates into fatty acids. The process of de novo lipogenesis is covered in depth within this volume. The book is an important contribution to the vast literature and ongoing research on liver function.

Clinical Anatomy of the Shoulder - An Atlas (Hardcover, 1st ed. 2017): Murat Bozkurt, Halil Ibrahim Acar Clinical Anatomy of the Shoulder - An Atlas (Hardcover, 1st ed. 2017)
Murat Bozkurt, Halil Ibrahim Acar
R2,652 Discovery Miles 26 520 Ships in 10 - 15 working days

This book provides detailed information on functional anatomy, physical examination, and clinical radiology of the shoulder with a view to enabling the clinician to identify the most suitable treatment approach to different shoulder joint pathologies. In addition, it describes the arthroscopic treatment techniques most frequently employed in patients with these conditions and presents numerous arthroscopic images detailing characteristic findings. The shoulder is widely regarded as the most complex joint in the human body, displaying the widest range of motion. Knowledge of normal and pathological anatomy, ability to perform a proper physical examination, and appropriate selection of imaging modalities and interpretation of imaging appearances, often in close collaboration with an imaging expert, are all vital for correct diagnosis and choice of treatment approach. Surgeons and trainees will find this richly illustrated book to be an excellent educational guide and an instructive source of stepwise guidance from clinical presentation to achievement of desired treatment outcomes.

Growth Hormone Deficiency - Physiology and Clinical Management (Hardcover, 1st ed. 2016): Laurie E. Cohen Growth Hormone Deficiency - Physiology and Clinical Management (Hardcover, 1st ed. 2016)
Laurie E. Cohen
R3,662 Discovery Miles 36 620 Ships in 12 - 17 working days

Providing the most current information on the function of human growth hormone (GH) and the consequences of its deficiency, this practical yet comprehensive text is divided into three sections. Part one describes the mechanisms of GH secretion and action, including the physiology of GH and its regulation by sex steroids and thyroid hormones, the effects of both under nutrition and obesity on GH secretion, and the metabolic effects of human recombinant GH therapy. The second section covers diagnostic strategies and tests for GH deficiency in both children and adults, including MRI of the pituitary. The final section describes the different etiologies of GH deficiency, from molecular mechanisms and gene abnormalities to cranial radiation and traumatic brain injury, along with syndromes related to this deficiency. Presenting underlying mechanisms and pathologies, as well as diagnostic methods, Growth Hormone Deficiency will provide the most up-to-date essential information and evidence on this condition for the clinical endocrinologist.

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