Carry the same authoritative, useful knowledge that readers of Guyton and Hall have come to trust - in an easily accessible, pocket format. Pocket Companion to Guyton and Hall Textbook of Medical Physiology, 14th Edition, echoes the structure and content of the world's foremost physiology textbook, making it ideal for a quick, portable review or entry point into complex topics. Grasp key information quickly thanks to concise, readable text. Benefit from updated content of the 14th edition of the bestselling text in a condensed synopsis format. Quickly locate more in-depth discussions inside the parent text with abundant cross-references and a parallel chapter organization. Enhanced eBook version included with purchase. Your enhanced eBook allows you to access all of the text, figures, and references from the book on a variety of devices.

Standardizing Pharmacology: Assays and Hormones, Volume Two in the Discoveries in Pharmacology series, presents selected articles from historic discoveries that are enhanced with commentary from contemporary scholars who present discussions on the importance of each chapter, along with an updated bibliography on the subject and contributions from a Nobel Prize winner and other pioneers in pharmacology. Academic and industry researchers in pharmacology and medicine, as well as advanced students will find this series a useful teaching tool and launch to new discoveries. Sections cover key discoveries in receptor theory, pharmacological methods and the development of hormone therapy, including J. Parascandola on the development of receptor theory, R.S. Yalow on radioimmunoassay, M. van Rossum and J.T L.A. Hurkmans on bioassays, M. Tausk on androgen therapy and C. Djerassi on oral contraceptives, with commentaries from experts such as T. Hoekfelt and V.C. Jordan.

Pediatric arrhythmias present numerous challenges to pediatric cardiologists and other practitioners who see pediatric patients, including pediatricians, family physicians, emergency physicians, residents, fellows, and other clinicians. Arrhythmias in Children: A Case-Based Approach features practical methods for diagnosing and treating arrhythmias in these patients across all settings. Nearly three dozen real-world scenarios are presented, followed by a discussion of the diagnosis, clinical thinking process involved, treatment options, expected outcomes, and how to manage anticipated and unanticipated outcomes. These practical, realistic cases provide a unique and engaging way of approaching these challenging patient scenarios. Uses a case-based approach for a full spectrum of pediatric arrythmias in the newborn, child, pre-teen, and teenager. Presents history and physical, differential diagnoses, tests to order, and practical plans of action. Includes a section on arrythmias in special circumstances. Models clinical thinking skills for a wide number of real-world patient situations. Reviews pertinent clinical guidelines, treatment, and follow up.

A successful Wall Street trader turned neuroscientist reveals how risk taking and stress transform our body chemistry
Before he became a world-class scientist, John Coates ran a derivatives trading desk in New York City. He used the expression "the hour between dog and wolf" to refer to the moment of Jekyll-and-Hyde transformation traders passed through when under pressure. They became cocky and irrationally risk-seeking when on a winning streak, tentative and risk-averse when cowering from losses. In a series of groundbreaking experiments, Coates identified a feedback loop between testosterone and success--one that can cloud men's judgment in high-pressure decision-making. Coates demonstrates how our bodies produce the fabled gut feelings we so often rely on, how stress in the workplace can impair our judgment and even damage our health, and how sports science can help us toughen our bodies against the ravages of stress. Revealing the biology behind bubbles and crashes, "The Hour Between Dog and Wolf "sheds new and surprising light on issues that affect us all.

Currently, there is a critical need to integrate diversity and inclusion into health professions curricula and to diversify educators' approaches to teaching. The COVID-19 pandemic has most recently highlighted the systemic barriers that exist for our most vulnerable patients. To address these inequities, it is important to promote diversity and inclusion in thought, practice, and curricular content. Social and cultural experiences uniquely influence the learning experience, so a plurality of perspectives should be represented in educational material and seen in the classroom. Cases on Diversity, Equity, and Inclusion for the Health Professions Educator serves as a tool to enhance the structure and competencies of learners in health professions. This case book engages both learners and educators in health professions in robust discussions that serve to enhance awareness and knowledge around these issues with the expectation that knowledge will translate into practices that eventually reduce health inequities. Covering topics such as ableism, barriers to healthcare access, and mental health stigma, this case book is an indispensable resource for health professionals, educators and students in the health professions, hospital administrators, medical librarians, sociologists, government officials, researchers, and academicians.

Exploring the potential of poetry and poetic language as a means of conveying perspectives on ageing and later life, this book examines questions such as 'how can we understand ageing and later life?' and 'how can we capture the ambiguities and complexities that the experiences of growing old in time and place entail?' As poetic language illuminates, transfigures and enchants our being in the world, it also offers insights into the existential questions that are amplified as we age, including the vulnerabilities and losses that humble us and connect us. Literary gerontology and narrative gerontology have highlighted the importance of linguistic representations of ageing. While the former has been concerned primarily with the analysis of published literary works, the latter has foregrounded the individual and collective meaning making through narrative resources in old age. There has, however, been less interest in how poetic language, both as a genre and as a practice, can illuminate ageing. This volume suggests a path towards the poetics of ageing by means of presenting analyses of published poetry on ageing written by poets from William Shakespeare to Wallace Stevens; the use of reading and writing poetry among ordinary people in old age; and the poetic nuances that emerge from other literary practices and contexts in relation to ageing - including personal poetic reflections from many of the contributing authors. The volume brings together international scholars from disciplinary backgrounds as diverse as cultural psychology, literary studies, theology, sociology, narrative medicine, cultural gerontology and narrative gerontology, and will deploy a variety of empirical and critical methodologies to explore how poetry and poetic language may challenge dominant discourses and illuminate alternative understandings of ageing.

Anti-Aging Pharmacology provides an overview of current research aimed at the pharmacological modulation of aging, including a discussion of the growing number of novel drug classes with promising anti-aging potential. The aging process is the main risk factor for all chronic diseases affecting the elderly. With lifespans extending across the globe, these chronic diseases are placing a larger burden on individuals and health care systems. Therefore, slowing down the aging rate could be more effective in delaying aging-associated chronic disorders than combating them one by one, which is the conventional approach in a current disease-based pharmacological paradigm. This book contains the work of the world's leading researchers in the field, including sections on the conceptual and methodological background of anti-aging pharmacology, the basic classes of anti-aging drugs, phytochemicals, outcomes of anti-aging developments and future directions. This book will be of interest to a wide audience, ranging from pharmacologists, medicinal chemists and academic researchers in gerontology, biomedical sciences and those in medical practice.

Epigenetics in Organ Specific Disorders, a new volume in the Translational Epigenetics series, provides a foundational overview and nuanced analysis of epigenetic gene regulation distinct to each organ type and organ specific disorders, fully elucidating the epigenetics pathways that promote and regulate disease. After a brief introduction, chapter authors compare epigenetic regulations across normal and disease conditions in different organ tissues, exploring similarities and contrasts. The role of epigenetic mechanisms in stem cells, cell-matrix interactions and cell proliferation, cell migration, cellular apoptosis, necrosis, pyknosis, tumor suppression, and immune responses across different organ types are examined in-depth. Organ specific epigenetic mechanisms and biomarkers of early use in developing drugs, which can selectively target the organ of interest, are also explored to enable new precision therapies.

Applied Environmental Metabolomics: Community Insights and Guidance from the Field brings together contributions from global experts who have helped to define and develop the exciting and rapid advances that are taking place in the field of environmental metabolomics. This book is aimed at expert users, students, researchers, and academics in metabolomics and systems biology. It not only demonstrates the best practice in experimental design but also provides insight into state-of-the-art instrumentation and the depth of analysis one can expect to get by using various sampling, chromatographic, mass spectrometric, and nuclear magnetic resonance (NMR) techniques. Common experimental and technical pitfalls are also highlighted. This book provides a unique insight into the world of environmental metabolomics and will help the practicing scientist avoid repeating similar costly mistakes, steering them efficiently toward the generation of high-quality data and high-impact publications.

Discoveries in Pharmacology: Volume 1: Nervous system and hormones (2nd Ed.) presents selected articles from the historic Discoveries in Pharmacology series enhanced with commentary from contemporary scholars about the reception and importance of the chapter along with an updated bibliography on the subject with contributions from a Nobel Prize winner and other pioneers in Pharmacology. The Discoveries in Pharmacology series brought acknowledged experts in their fields together to provide first-hand accounts of important pharmacological discoveries discussing the scientific background and stories behind these pivotal moments. They allow a true understanding of the means by which pharmacological discoveries are made. This volume brings forth discussions on key discoveries in psycho- and neuro-pharmacology, haemodynamics, and hormones including chapters on antipsychotic agents by Nobel winner Anders Carlsson, Willy Haefely on benzodiazepine, and butyrophenone-type neuroleptics by P. A. J. Janssen and J. P. Tollenaere. Academic and industry researchers in pharmacology and medicine, as well as advanced students in the area will find this series a useful teaching tool and launch to new discoveries. Chapters can also be used to supplement course material in pharmacology and medical courses. It will also be of interest to those who are interested in the history of medicine.

The Skeletal System, Second Edition is a modern update of the bestselling, classic The Skeletal System chart dating back to 1947. The illustrations are vividly colored and finely detailed, and structures are clearly labeled. The chart features three large illustrations showing the anterior, lateral, and posterior views of the skeletal system. Eight smaller illustrations show: Portion of Long Bone Auditory Ossicles (Left Medial View 3X) Ligaments of Right hand (Dorsal and Palmar Views) Ligaments of Right Foot (Dorsal and Plantar View) Right Knee Joint (Anterior and Posterior Views) 20" x 26" heavy paper laminated with grommets at top corners

John Rebus stands accused: on trial for a crime that could put him behind bars for the rest of his life. Although it's not the first time the legendary detective has taken the law into his own hands, it might be the last. What drove a good man to cross the line? Or have times changed, and the rules with them? Detective Inspector Siobhan Clarke faces Edinburgh's most explosive case in years, as a corrupt cop goes missing after claiming to harbour secrets that could sink the city's police force. But in this investigation, it seems all roads lead to Rebus - and Clarke's twin loyalties to the public and the police will be tested to their limit. A reckoning is coming - and John Rebus may be hearing the call for last orders...

Principles and Practice of Ovarian Tissue Cryopreservation and Transplantation provides methods and techniques of ovarian tissue harvesting and cryopreservation, including instructional videos. This book will benefit a wide audience, guiding infertility specialists, fellows, residents, reproductive surgeons, reproductive endocrinologists, pediatric surgeons, embryologists, infertility nurses and gynecologists. Ovarian cryopreservation and transplantation is rapidly gaining acceptance as a successful and established fertility preservation strategy in cancer patients and beyond. Unlike other fertility preservation strategies, it can be performed in children as well as adults, and can be helpful in restoring natural ovarian function and fertility, hence this is a welcomed resource on the topic.

Renowned for its comprehensive coverage and engaging, storytelling approach, the bestselling Moore's Clinically Oriented Anatomy, 9th Edition, guides students from initial anatomy and foundational science courses through clinical training and practice. A popular resource for a variety of programs, this proven text serves as a complete reference, emphasizing anatomy that is important in physical diagnosis for primary care, interpretation of diagnostic imaging, and understanding the anatomical basis of emergency medicine and general surgery. The 9th Edition reflects the latest changes in the clinical application of anatomy as well as preparation for the USMLE while maintaining the highest standards for scientific and clinical accuracy. NEW! Sex and gender content clarifies important gender considerations and reflects an equitable focus on female as well as male anatomy. Updated medical imaging and integrated surface anatomy within each chapter clearly demonstrates the relationship between anatomy, physical examination, and diagnosis. Extensively revised Clinical Blue Boxes highlight the practical applications of anatomy, accompanied by helpful icons, illustrations, and images that distinguish the type of clinical information covered. Updated introduction establishes the foundational understanding of systemic information and basic concepts essential to success from the classroom to the dissection lab. Revised comprehensive surface anatomy photographs ensure accurate, effective physical examination diagnoses with integrated natural views of unobstructed surface anatomy and illustrations superimposing anatomical structures with landmarks for more accurate physical examination. Insightfully rendered, anatomically accurate illustrations, combined with many photographs and medical images, strengthen comprehension of anatomical concepts and retention of "mental images" of anatomical structures. Bottom Line boxes provide detailed summaries at a glance and underscore the "big-picture" perspective. Illustrated tables clarify complex information about muscles, veins, arteries, nerves, and other structures for easy study and review. Chapter outlines help students find key information quickly and efficiently.

Genomic and Precision Medicine: Oncology, Third Edition focuses on the applications of genome discovery as research points to personalized cancer therapies. Each chapter is organized to cover the application of genomics and personalized medicine tools and technologies to a) Risk Assessment and Susceptibility, b) Diagnosis and Prognosis, c) Pharmacogenomics and Precision Therapeutics, and d) Emerging and Future Opportunities in the field.

Muscle Biology: The Life History of a Muscle looks at the story of a muscle from its embryonic beginnings, through its growth and ability to adapt to changing functional circumstances during adult life, to its eventual decline in both structure and function as old age progresses. Injury occurs to muscle during normal activity, after trauma, and during the source of certain diseases. Chapters on both muscle regeneration and muscle diseases emphasize the possibilities and limitsations of the healing capacity of muscle fibers. Muscle Biology begins with a brief review about the structure and function of a normal mature muscle and then proceeds to follow the developmental history of a muscle from the embryo to old age in a manner that gives the reader a perspective about not only developmental controls but also how at any stage of development a muscle is able to adapt to its functional environment. The book discusses both normal and abnormal changes in the muscle, the mechanisms behind those changes and how to mitigate deleterious changes from disease, 'normal' aging, and disuse/lack of physical activity. This is a must-have reference for students, researchers and practitioners in need of a comprehensive overview of muscle biology.

Modeling Electrochemical Dynamics and Signaling Mechanisms in Excitable Cells with Pathological Case Studies covers the neuronal cell communication system in excitable cells, recognizing the most relevant mechanisms of cell communication. Along with new findings in biotechnology, medicine and pathological cases for clinicians, the book highlights electrochemical potential in living nerve and muscle cells. Written for physiological scientists, pharmaceutical scientists, medical doctors, biologists and physicists, this book an essential read for a real understanding of the signals as we see them.

Bioengineering is a rapidly expanding interdisciplinary field that encompasses application engineering techniques in the field of mechanical engineering, electrical, electronics and instrumentation engineering, and computer science and engineering to solve the problems of the biological world. With the advent to digital computers and rapidly developing computational techniques, computer simulations are widely used as a predictive tool to supplement the experimental techniques in engineering and technology. Computational biomechanics is a field where the movements biological systems are assessed in the light of computer algorithms describing solid and fluid mechanical principles. This book outlines recent developments in the field of computational biomechanics. It presents a series of computational techniques that are the backbone of the field that includes finite element analysis, multi-scale modelling, fluid-solid interaction, mesh-less techniques and topological optimization. It also presents a series of case studies highlighting applications of these techniques in different biological system and different case studies detailing the application of the principles described earlier and the outcomes. This book gives an overview of the current trends and future directions of research and development in the field of computational biomechanics. Overall, this book gives insight into the current trends of application of intelligent computational techniques used to analyse a multitude of phenomena the field of biomechanics. It elaborates a series of sophisticated techniques used for computer simulation in both solid mechanics, fluid mechanics and fluid-solid interface across different domain of biological world and across various dimensional scales along with relevant case studies. The book elucidates how human locomotion to bacterial swimming, blood flow to sports science, these wide range of phenomena can be analyzed using computational methods to understand their inherent mechanisms of work and predict the behavior of the system. The target audience of the book will be post-graduate students and researchers in the field of Biomedical Engineering. Also industry professionals in biomedical engineering and allied disciplines including but not limited to kinesiologists and clinicians, as well as, computer engineers and applied mathematicians working in algorithm development in biomechanics.