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Radiation-Induced Processes of Adaptation - Research by statistical modelling (Hardcover, 2013 ed.)
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Radiation-Induced Processes of Adaptation - Research by statistical modelling (Hardcover, 2013 ed.)
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In recent decades radiobiologists' efforts have been directed at
identifying the mechanisms of radiation effects; the general
mechanisms have since been studied extensively. This book describes
and analyzes radiation-induced adaptation as processes produced in
cells, tissues, and populations. This viewpoint helps to understand
the nature and factors of induced processes, to determine the
characteristics of observed radiation effects and their
limitations. The investigations presented here were founded on
proper lab experiments, ecological studies of plant population
growth near an operating nuclear power plant and a thorough
epidemiological examination of human populations living in
territories polluted fifty years ago, as well as on relevant
published data. This research demonstrates the radiation-induced
adaptation processes that continue even when the radiation itself
is no longer at a critical background level. The investigations
utilized the method of statistical modeling on the basis of
distributions on the number of abnormalities. This method allows us
to investigate the processes induced by low-dose factors when
accompanied by Darwinian selection in different systems; the
distribution parameters can then be used to study the
characteristics of adaptation processes and system resistance. The
consequences of background-level radiation continue to provoke
debate, and the mathematical bases of the adaptation model are
shown, while due consideration is paid to the components of
adaptation: instability, selection, and proliferation. The book
will be especially useful to specialists in radiation pollution,
ecology, epidemiology, and radiology for studies of
radiation-induced processes; the method presented here can also be
adapted to investigate low-dose effects in other fields. In
addition, the book presents a number of reviews in the fields of
radiation biology, including pioneering investigations in Russia
which were previously unavailable to Western scientists.
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