Vicinal Diaryl-Substituted Heterocycles: A Gold Mine for the Discovery of Novel Therapeutic Agents draws together all of the key information about these compounds in one place for the first time. Following an informative overview of the importance of these structures to the discovery of potential therapeutic agents, the text goes on to outline the main compound types, with each chapter focusing on the activities of a different structure. Designed to support researchers by consolidating this important information in a single, practical guide, the authors hope to encourage further advancement and development in the discovery of novel therapeutic agents. As flexible building blocks for the production of novel compounds, vicinal diaryl-substituted heterocycles are a rich source of leads for the development of new drugs. Their adaptability means that they can be used to produce structures with a broad range of attractive characteristics, and a large number of vicinal diaryl-substituted heterocyclic compounds have already been synthesized and investigated by medicinal chemists as promising lead molecules.

Intelligent Data Analytics for Solar Energy Prediction and Forecasting: Advances in Resource Assessment and PV Systems Optimization explores the utilization of advanced neural networks, machine learning and data analytics techniques for solar radiation prediction, solar energy forecasting, installation and maximum power generation. The book addresses relevant input variable selection, solar resource assessment, tilt angle calculation, and electrical characteristics of PV modules, including detailed methods, coding, modeling and experimental analysis of PV power generation under outdoor conditions. It will be of interest to researchers, scientists and advanced students across solar energy, renewables, electrical engineering, AI, machine learning, computer science, information technology and engineers. In addition, R&D professionals and other industry personnel with an interest in applications of AI, machine learning, and data analytics within solar energy and energy systems will find this book to be a welcomed resource.

Fused Pyranones: Multifaceted Building Blocks for Molecular Diversity covers the synthesis and chemical reactivity of fused pyranone ring systems, such as coumarin, isocoumarin, chromonone, chroman-4-one, and others, as well as their applications in the fields of drug discovery and material sciences. Mechanisms of the chemical reactions are covered, along with the steps to formation of final products. This book is ideal for organic, medicinal and material chemists and researchers working to build target compounds for pharmaceuticals and materials, as well as those working in food supplements, perfumery, and cell and animal imaging.

Green Chemistry Approaches to Environmental Sustainability: Status, Challenges and Prospective provides a comprehensive and complete overview of the emerging discipline of green chemistry and fundamental chemical principles. The book bridges the gap between research and industry by offering a systematic overview of current available sustainable materials and related information on new materials' suitability and potential for given projects. Along the way, the book examines natural and biodegradable materials while also presenting materials with multifunctional properties. Topics addressed in this book will be major accomplishments for sustainable developments in biofuels, renewable energies, and in the remediation of pollutants in water, air and soil.

Bioaerosols Emission from Anthropogenic Sources: Influencing Factors, Microbial Diversity, Epidemiological Threats, and Control Approaches covers various sources of biohazards and their associated risk factors. These air contaminants are developing concerns to people and the environment and must be addressed to avert future dangers. As little is known about their precise sources, controlling variables, microbial diversity, the involvement of co-pollutants, and dispersion and control methods, this book  will assist stakeholders, including the public, government officials, and policymakers in developing successful strategies for ensuring society's safety.

Machine learning (ML) and the internet of things (IoT) are the top technologies used by businesses to increase efficiency, productivity, and competitiveness in this fast-paced digital era transformation. ML is the key tool for fast processing and decision making applied to smart city applications and next-generation IoT devices, which require ML to satisfy their working objective. IoT technology has proven efficient in solving many real-world problems, and ML algorithms combined with IoT means the fusion of product and intelligence to achieve better automation, efficiency, productivity, and connectivity. Machine Learning-Enabled IoT for Smart Applications Across Industries highlights the importance of ML for IoT’s success and diverse ML-powered IoT applications. This book addresses the problems and challenges in energy, industry, and healthcare and solutions proposed for ML-enabled IoT and new algorithms in ML. It further addresses their accuracy for existing real-time applications. Covering topics such as agriculture, pattern recognition, and smart applications, this premier reference source is an essential resource for engineers, scientists, educators, students, researchers, and academicians.

Nanotechnology in Human Health: Current Research and Future Trends details the various challenges faced in human healthcare settings and how nanotechnology can be used to target and improve outcomes. The book describes the application of nanoparticles in the diagnosis of human diseases, including metabolic diseases, cancer, bacterial infection, organ degeneration and the various targeted, nano-based treatments available. Several chapters look at how microbial biofilms - a key clinical concern - can be mitigated using nanomaterials and nanotechnology. In addition, the book covers how different nanoparticle types can be utilized as therapeutic agents. This book combines materials science concepts and techniques with clinical insights and understanding to provide an interdisciplinary reference for materials scientists, microbiologists, biomedical engineers and clinicians with an interest in nanotechnology.

Microplastics and Nanoplastics: Occurrence, Environmental Impacts and Treatment Processes comprehensively illustrates the microplastics and nanoplastics pollution in different waters, wastewaters and terrestrial environment, and the possibilities of their removal/degradation. It provides a through and exhaustive discussion of the ongoing research and future perspectives of micro/nanoplastics, their interaction with other chemicals, the advanced degradation technologies and their impacts on the ecosystem. Micro- and nano-plastic pollution is an important topic in academia and industry and is gaining considerable attention in the society due to the concerns related to plastics. In addition to presenting the current issues and trends, this book also addresses some concrete solutions to mitigate this emerging environmental threat. This book is written at an advanced level to address the needs of researchers, students as well as people outside the field of environment technology including, industries, government sectors, business establishments and public interest groups.

Bioinformatics in Agriculture: Next Generation Sequencing Era is a comprehensive volume presenting an integrated research and development approach to the practical application of genomics to improve agricultural crops. Exploring both the theoretical and applied aspects of computational biology, and focusing on the innovation processes, the book highlights the increased productivity of a translational approach. Presented in four sections and including insights from experts from around the world, the book includes: Section I: Bioinformatics and Next Generation Sequencing Technologies; Section II: Omics Application; Section III: Data mining and Markers Discovery; Section IV: Artificial Intelligence and Agribots. Bioinformatics in Agriculture: Next Generation Sequencing Era explores deep sequencing, NGS, genomic, transcriptome analysis and multiplexing, highlighting practices forreducing time, cost, and effort for the analysis of gene as they are pooled, and sequenced. Readers will gain real-world information on computational biology, genomics, applied data mining, machine learning, and artificial intelligence. This book serves as a complete package for advanced undergraduate students, researchers, and scientists with an interest in bioinformatics.

Advances in Remediation Techniques for Polluted Soils and Groundwater focuses on the thematic areas for assessment, mitigation, and management of polluted sites. This book covers advances in modelling approaches, including Machine Learning (ML)/ Artificial Intelligence (AI) applications; GIS and remote sensing; sensors; impacts of climate change on geogenic contaminants; and socio-economic impacts in the poor rural and urban areas, which are lacking in a more comprehensive manner in the previous titles. This book encompasses updated information as well as future directions for researchers working in the field of management and remediation of polluted sites.

Hazardous Waste Management: An Overview of Advanced and Cost-Effective Solutions includes the latest practical knowledge and theoretical concepts for the treatment of hazardous wastes. The book covers five major themes, namely, ecological impact, waste management hierarchy, hazardous waste characteristics and regulations, hazardous wastes management, and future scope of hazardous waste management. It serves as a comprehensive and advanced reference for undergraduate students, researchers and practitioners in the field of hazardous wastes and focuses on the latest emerging research in the management of hazardous waste, the direction in which this branch is developing as well as future prospects. The book deals with all these components in-depth, however, particular attention is given to management techniques and cost-effective, economically feasible solutions for hazardous wastes released from various sources.

Metal Matrix Composites by Friction Stir Processing discusses the capabilities of utilizing friction stir processing (FSP) as a tool to manufacture new materials, such as composites. FSP is considered a tool for grain refinement. However, this work illustrates how FSP has a wider capability due to the material flow and mixing the process offers. This book highlights such aspects by demonstrating the ability of the process to incorporate a second phase and make metal matrix composites (MMCs). The book covers the current research on processing MMCs by FSP, and presents a novel approach of making ductile MMCs by FSP using metal particle reinforcements.

Advanced Spinel Ferrite Nanocomposites for Electromagnetic Interference Shielding Applications presents recent developments in advanced spinel ferrite nanocomposites for electromagnetic interference shielding, including microwave absorption applications. The book includes the basics of shielding mechanisms, synthesis of advanced nanocomposites, and characterization, as well as results analysis. It also discusses the relationship between nanocomposite structure and physical properties. The book systematically explores how spinel ferrite nanoparticle composites are utilized with polymer, carbon source materials (carbon nanotube, graphene, etc.), metal nanoparticles, metal oxide nanoparticles, hard ferrite nanoparticles, glass, rubber, wood, fabrics/textiles, and cement/concrete in the development of advanced spinel ferrite nanocomposites for electromagnetic interference shielding application. Academics, scientists, engineers, students, and industrial researchers will find this book beneficial.

Endophytic Fungi: The Full Story of the Untapped Treasure covers the developments in endophytic fungal research from beginning to the end by the eminent researchers involved in the field. It sheds light on the endophytic fungal current research, challenges, and future possibilities, the trending recent topics in the plant-fungal endophytes' biodynamics for sustainable development of bioproducts and its applications are supported in large-scale biosynthesis of industrially and pharmaceutical important biomolecules.The highlights of Endophytic Fungi: The Full Story of the Untapped Treasure are the bioprospecting and applied aspects of endophytic fungi. Practical applications of such endophytes are discussed in detail. Further, it reviews recent strategies on alternative sustainable sources of medicines such as secondary metabolites of fungi instead of over collection of plants under prohibiting of biodiversity conventions. The uniqueness of the Endophytic Fungi is the inclusion of updated bioinformatics-based strategies and its importance in bioactive molecules produced by endophytic fungi. Endophytic Fungi addresses one of the most eminent issues in this field: "how to translate the potential that endophytic fungi hold in stable practical application."

Fundamentals of Recombinant Protein Production, Purification and Characterization is organized into nine chapters in a logical fashion that cover an introduction to recombinant proteins and expression in different host expression systems, extraction, purification and analysis of proteins. This important reference features protocols, along with the advantages and disadvantage of each expression hosts and characterization technique (presented in tabular format) and offers detailed coverage of all aspects of protein production and processing (upstream and downstream processing) in one place. Finally, the book ends with different characterization techniques. Production of recombinant proteins for biotechnological and therapeutic applications at a large scale is an essential need of mankind. With the huge application potential of therapeutic and industrial proteins, there has been increasing demand for effective and efficient bioprocessing strategies. Recent progress around recombinant DNA technologies and bioprocessing strategies has paved the way for efficient production of recombinant proteins. Important factors such as insolubility and cost of production need to be considered for large scale production of these recombinant proteins.

Microbial biofilms: Role in Human Infectious Diseases focuses on new and emerging concepts in microbial biofilm research, such as the mechanisms of biofilm formation, biofilm-induced pathogenesis, biofilm detection/and diagnosis, gene exchange within biofilms, strategies to control microbial biofilms and the burden of biofilm associated infections. In addition, it highlights the various anti-biofilm strategies such as surface coating, signal quenching, novel compounds that can be translated to curb biofilm-associated infections and the escalation of antimicrobial resistance determinants. Microbial biofilms can be a serious problem in medical settings as they are associated with significant mortality and morbidity. Infection related to biofilms increases recovery time and the cost of disease management. Biofilms are resistant to known antibiotics and human defense mechanism. In addition, due to close proximity of microbes within biofilms, increase genetic transformation has been detected results in increases frequency of antibiotic gene spread. With the advancement in science and technology, novel strategies have been proposed to combat the impact of biofilms on human health.

New and Future Developments in Microbial Biotechnology and Bioengineering: Microbial Biofilms is divided into three sections: microbial adhesion/biofilms in medical settings, microbial adhesion/biofilms in agriculture, and microbial adhesion/biofilm in the environment and industry. Chapters cover adhesion and biofilm formation by pathogenic microbes on tissue and on indwelling medical devices, including sections on human infections, microbial communication during biofilm mode of growth, host defense and antimicrobial resistance, and more. Other sections cover the biofilms of agriculturally important and environmental friendly microbes, including biofilm formation on plants, in soil, and in aquatic environments. Finally, the latest scientific research on microbial adhesion and biofilm formation in the environment and in industry is covered.