This interdisciplinary book examines Brexit from a political economy perspective, enriched by insights from scholars of political science, history and law. Shedding light on the key motivations for Brexit, this incisive book seeks to better understand what shapes the UK's political and economic preferences and the fundamental causes and issues that have moulded its stance on the EU. Political issues explored include the political rationality of Brexit and the reasons for the UK's unsustainable position in the EU, specific UK sovereignty concerns in the absence of a written constitution, the issue of preferences, and the UK's prospective standing in the world post EU exit. Economic considerations such as the root causes of Brexit, examination of the properties of the single market and EU regulation, including the issue of the City of London, and the importance played by subjective wellbeing rather than economic growth are investigated, as well as the challenges to be confronted post-Brexit. The Politics and Economics of Brexit will be a key resource for scholars and students interested in the European Union, European governance and political economics. Analysing the Brexit impasse from 2016-2019, this comprehensive book will also be valuable to those working in comparative politics, international relations, business and industry. Contributors include: S. Baroncelli, A. Bongardt, R. Bourgeot, P. Della Posta, R. Di Quirico, E. Diodato, S. Giusti , S. Rehman, M. Rosini, L.S. Talani, F. Torres