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The title of this volume implies a progression of sorts from
species of molecular size to a product described on the basis of
continuum prop erties. The difference in approach from the
standpoint of molecular be havior, on the one hand-more the forte
of chemists-and from the standpoint of large-scale properties, on
the other-more the province of chemical engineers and materials
scientists-represents a severe cultural divide, but one with much
potential for creative input from both sides. Chapter 1 of this
volume attempts a broad survey of trends toward the synthesis of
large, well-defined molecular systems with interesting physical,
chemical, or material properties. Review articles with more de
tailed treatments are emphasized. In Chapter 2, Newkome and Moore
field summarize work on synthesis of /I cascade" molecules. Next,
Denti, Campagna, and Balzani describe the synthesis of assemblies
with con nected metal-containing chromophore units which transmit
electrons or electronic energy in defined ways. In Chapter 4 Wuest
describes the con struction of hydrogen-bonded organic networks,
and in Chapter 5 Michl defines a molecular-level construction set.
Finally, Jaszczak points out how nature's attempts over geological
time spans are emulated by recent human synthetic activity in the
fullerene arena, through the appearance of various morphologies of
natural graphite. The book concludes with a method for describing
fractal-like mole cules, and an index based on the method for
appropriate compounds described in the text."
The title of this volume implies a progression of sorts from
species of molecular size to a product described on the basis of
continuum prop erties. The difference in approach from the
standpoint of molecular be havior, on the one hand-more the forte
of chemists-and from the standpoint of large-scale properties, on
the other-more the province of chemical engineers and materials
scientists-represents a severe cultural divide, but one with much
potential for creative input from both sides. Chapter 1 of this
volume attempts a broad survey of trends toward the synthesis of
large, well-defined molecular systems with interesting physical,
chemical, or material properties. Review articles with more de
tailed treatments are emphasized. In Chapter 2, Newkome and Moore
field summarize work on synthesis of /I cascade" molecules. Next,
Denti, Campagna, and Balzani describe the synthesis of assemblies
with con nected metal-containing chromophore units which transmit
electrons or electronic energy in defined ways. In Chapter 4 Wuest
describes the con struction of hydrogen-bonded organic networks,
and in Chapter 5 Michl defines a molecular-level construction set.
Finally, Jaszczak points out how nature's attempts over geological
time spans are emulated by recent human synthetic activity in the
fullerene arena, through the appearance of various morphologies of
natural graphite. The book concludes with a method for describing
fractal-like mole cules, and an index based on the method for
appropriate compounds described in the text."
In 1995, Signal Transduction Protocols, edited by David A. Kendall
and Stephen J. Hill, was published in the Methods in Molecular
Biology series. This second edition represents an update to that
previous work with an emp- sis on new methodologies that have
developed in the last few years. The goal, then and now, is to
provide procedures written by experts with first-hand ex- rience in
a detail that goes far beyond what is generally encountered in the
"methods" section of most journals and thus actually permits a
particular p- cedure to be replicated. In addition, we have had as
a secondary goal the id- tification of protocols for the assay of
general classes of signal transduction components that, ideally,
can be adapted to the assay of any member of that class. The
ability to do this has resulted in large part from the use of
affini- based assays, the ease with which specific proteins can be
specifically tagged, and an explosion in the availability of highly
specific antibodies from comm- cial sources, especially antibodies
raised against signaling proteins of human origin. The number of
available approaches is, fortunately for those working in signaling
research, far too great to fit within the confines of this volume,
so hard choices as to what to include had to be made.
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