In multicellular organisms, communication between cells involves secretion of proteins that bind to receptors on neighboring cells. While this has been well documented, another mode of intercellular communication has recently become the subject of increasing interest: the release of exosomes. In cancer, tumor exosomes are involved in various aspects of pathogenesis, including proliferation, immunosuppression, and metastasis. Given the ability of exosomes to export unneeded endogenous molecules from cells, these structures hold great potential as anticancer therapeutic agents. They are also being studied as prognostic markers for cancer.

In multicellular organisms, communication between cells involves secretion of proteins that bind to receptors on neighboring cells. While this has been well documented, another mode of intercellular communication has recently become the subject of increasing interest: the release of exosomes. In cancer, tumor exosomes are involved in various aspects of pathogenesis, including proliferation, immunosuppression, and metastasis. Given the ability of exosomes to export unneeded endogenous molecules from cells, these structures hold great potential as anticancer therapeutic agents. They are also being studied as prognostic markers for cancer.

This book constitutes the thoroughly refereed post conference proceedings of the 6th IFIP WG 9.2, 9.6/11.7, 11.4, 11.6/PrimeLife International Summer School, held in Helsingborg, Sweden, in August 2010. The 27 revised papers were carefully selected from numerous submissions during two rounds of reviewing. They are organized in topical sections on terminology, privacy metrics, ethical, social, and legal aspects, data protection and identity management, eID cards and eID interoperability, emerging technologies, privacy for eGovernment and AAL applications, social networks and privacy, privacy policies, and usable privacy.

NewInternetdevelopmentsposegreaterandgreaterprivacydilemmas. Inthe- formation Society, the need for individuals to protect their autonomy and retain control over their personal information is becoming more and more important. Today, informationandcommunicationtechnologies-andthepeopleresponsible for making decisions about them, designing, and implementing them-scarcely consider those requirements, thereby potentially putting individuals' privacy at risk. The increasingly collaborative character of the Internet enables anyone to compose services and contribute and distribute information. It may become hard for individuals to manage and control information that concerns them and particularly how to eliminate outdated or unwanted personal information, thus leavingpersonalhistoriesexposedpermanently. Theseactivitiesraisesubstantial new challenges for personal privacy at the technical, social, ethical, regulatory, and legal levels: How can privacy in emerging Internet applications such as c- laborative scenarios and virtual communities be protected? What frameworks and technical tools could be utilized to maintain life-long privacy? DuringSeptember3-10,2009, IFIP(InternationalFederationforInformation Processing)workinggroups9. 2 (Social Accountability),9. 6/11. 7(IT Misuseand theLaw),11. 4(NetworkSecurity)and11. 6(IdentityManagement)heldtheir5th InternationalSummerSchoolincooperationwiththeEUFP7integratedproject PrimeLife in Sophia Antipolis and Nice, France. The focus of the event was on privacy and identity managementfor emerging Internet applications throughout a person's lifetime. The aim of the IFIP Summer Schools has been to encourage young a- demic and industry entrants to share their own ideas about privacy and identity management and to build up collegial relationships with others. As such, the Summer Schools havebeen introducing participants to the social implications of information technology through the process of informed discussion.