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Major advances in genetics, immunology, and endocrinology have
necessitated a new edition of this best-selling text. However,
despite the advances, recurrent pregnancy loss presents a
frustrating clinical problem. There is still disagreement about the
number of pregnancy losses which warrant investigation and
treatment and about which investigations should be performed. This
third edition provides an authoritative and comprehensive update on
advances in the understanding and management of this troubling
phenomenon, covering both basic scientific topics such as genetics
and cytokines, and profiles major advances in immunology,
endocrinology, and thrombotic mechanism. Clinical research is
discussed, as is assessment of results when applying an
evidence-based approach or a more personalised approach, which is
now becoming possible due to advances in the diagnosis of cause.
There are lively debates on the role of progestogens and
immunotherapy, which remain controversial. Designed for specialists
working in reproductive medicine clinics and those involved with
maternal-fetal care, the book is also ideal for generalists and
gynecologists seeking a comprehensive view of developments in the
field.
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