0
Your cart

Your cart is empty

Browse All Departments
  • All Departments
Price
  • R5,000 - R10,000 (4)
  • -
Status
Brand

Showing 1 - 4 of 4 matches in All Departments

Biological Reactive Intermediates V - Basic Mechanistic Research in Toxicology and Human Risk Assessment (Hardcover, 1996 ed.):... Biological Reactive Intermediates V - Basic Mechanistic Research in Toxicology and Human Risk Assessment (Hardcover, 1996 ed.)
Robert R. Snyder, James J. Kocsis, I.Glenn Sipes, George F. Kalf, David J. Jollow, …
R5,858 Discovery Miles 58 580 Ships in 10 - 15 working days

Much of organic chemistry is based on the ability of suitably structured chemicals to bind together through the formation of covalent bonds. Biochemistry is replete with exam ples of enzymatically catalyzed reactions in which normal body constituents can be linked through covalent bonds during the process of intermediary metabolism. The finding that xenobiotic chemicals that enter the body from the environment, are metabolized to highly reactive species, and then covalently react with cellular macromolecules to induce toxic and carcinogenic effects was an observation that spawned the research featured in the Fifth International Symposium on Biological Reactive Intermediates (BRI V). The group of investigators that became fascinated with this process and its signifi cance in terms of human health began their discussions in Turku, Finland (J 975), and continued them at Guildford, England (1980), College Park, Maryland (1985), Tucson, Arizona (1990), and Munich, Germany (1995). Among the results were a series of reports listed below, as well as the book for which this serves as the Preface. * Jollow, DJ., Kocsis, J.J., Snyder, R. and Vainio, H. (eds), Biological Reactive Intermediates: Formation, Toxicity and Inactivation, Plenum Press, NY, 1975. * Snyder, R., Park, D.V., Kocsis, J.J., Jollow, D.V., Gibson, G.G. and Witmer, C.M. (eds), Biological Reactive Intermediates II: Chemical Mechanisms and Biological Effects, Plenum Press, N.Y., 1982.

Biological Reactive Intermediates Vi - Chemical and Biological Mechanisms in Susceptibility to and Prevention of Environmental... Biological Reactive Intermediates Vi - Chemical and Biological Mechanisms in Susceptibility to and Prevention of Environmental Diseases (Hardcover, 2001 ed.)
Patrick M. Dansette, Robert R. Snyder, Terrence J. Monks, David J. Jollow, I.Glenn Sipes, …
R5,806 Discovery Miles 58 060 Ships in 10 - 15 working days

Historically we have separated the disciplines of Chemistry and Biochemistry by recognizing that the distinguishing characteristic of Biochemistry is the catalysis of reactions by enzymes. Enzymes permit metabolic reactions which would otherwise require extremes of temperature, pressure or pH, often associated with Chemistry, to proceed under ambient conditions of the body. Under some conditions chemical reactions occur in vivo in which products of enzymatic reactions proceed to undergo further reactions non- enzymatically with cellular macromolecules. The results can often be seen as toxic or carcinogenic responses. The chemicals that initiate these reactions are termed "biological reactive intermediates. " The International Symposia on Biological Reactive Intermediates (BRI) began in 1975 at the University of Turku, Finland and have since convened at the University of Surrey, Guildford, The United Kingdom (1980), the University of Maryland, College Park, Maryland (1985), the University of Arizona, Tucson, Arizona (1990), the GSF Forschungszentrum and Technical University of Munich (1995) and, most recently, at the Universite Rene Descartes, Paris, France (2000). The Symposium was organized by an International Planning Committee co-chaired by P. Dansette (Paris, France) and TJ. Monks (Austin, Texas). The committee included: P. H. Beaune (Paris, France), M. De\aforge (Saclay, France), G. P. Gervasi (Pisa, Italy), G. G. Gibson (Guildford, UK), H. Greim (Munich, Germany), DJ. Jollow (Charleston, South Carolina), P. Moldeus (Sodertalje, Sweden), I. G. Sipes (Tucson, Arizona), R. Snyder PJ. van Bladderen (Zeist, The Netherlands). They were (Piscataway, New Jersey), and assisted by an International Scientific Program Advisory Committee which included: TJ.

Biological Reactive Intermediates Vi - Chemical and Biological Mechanisms in Susceptibility to and Prevention of Environmental... Biological Reactive Intermediates Vi - Chemical and Biological Mechanisms in Susceptibility to and Prevention of Environmental Diseases (Paperback, Softcover reprint of the original 1st ed. 2001)
Patrick M. Dansette, Robert R. Snyder, Terrence J. Monks, David J. Jollow, I.Glenn Sipes, …
R5,739 Discovery Miles 57 390 Ships in 10 - 15 working days

Historically we have separated the disciplines of Chemistry and Biochemistry by recognizing that the distinguishing characteristic of Biochemistry is the catalysis of reactions by enzymes. Enzymes permit metabolic reactions which would otherwise require extremes of temperature, pressure or pH, often associated with Chemistry, to proceed under ambient conditions of the body. Under some conditions chemical reactions occur in vivo in which products of enzymatic reactions proceed to undergo further reactions non- enzymatically with cellular macromolecules. The results can often be seen as toxic or carcinogenic responses. The chemicals that initiate these reactions are termed "biological reactive intermediates. " The International Symposia on Biological Reactive Intermediates (BRI) began in 1975 at the University of Turku, Finland and have since convened at the University of Surrey, Guildford, The United Kingdom (1980), the University of Maryland, College Park, Maryland (1985), the University of Arizona, Tucson, Arizona (1990), the GSF Forschungszentrum and Technical University of Munich (1995) and, most recently, at the Universite Rene Descartes, Paris, France (2000). The Symposium was organized by an International Planning Committee co-chaired by P. Dansette (Paris, France) and TJ. Monks (Austin, Texas). The committee included: P. H. Beaune (Paris, France), M. De\aforge (Saclay, France), G. P. Gervasi (Pisa, Italy), G. G. Gibson (Guildford, UK), H. Greim (Munich, Germany), DJ. Jollow (Charleston, South Carolina), P. Moldeus (Sodertalje, Sweden), I. G. Sipes (Tucson, Arizona), R. Snyder PJ. van Bladderen (Zeist, The Netherlands). They were (Piscataway, New Jersey), and assisted by an International Scientific Program Advisory Committee which included: TJ.

Biological Reactive Intermediates V - Basic Mechanistic Research in Toxicology and Human Risk Assessment (Paperback, Softcover... Biological Reactive Intermediates V - Basic Mechanistic Research in Toxicology and Human Risk Assessment (Paperback, Softcover reprint of the original 1st ed. 1996)
Robert R. Snyder, James J. Kocsis, I.Glenn Sipes, George F. Kalf, David J. Jollow, …
R5,630 Discovery Miles 56 300 Ships in 10 - 15 working days

Much of organic chemistry is based on the ability of suitably structured chemicals to bind together through the formation of covalent bonds. Biochemistry is replete with exam ples of enzymatically catalyzed reactions in which normal body constituents can be linked through covalent bonds during the process of intermediary metabolism. The finding that xenobiotic chemicals that enter the body from the environment, are metabolized to highly reactive species, and then covalently react with cellular macromolecules to induce toxic and carcinogenic effects was an observation that spawned the research featured in the Fifth International Symposium on Biological Reactive Intermediates (BRI V). The group of investigators that became fascinated with this process and its signifi cance in terms of human health began their discussions in Turku, Finland (J 975), and continued them at Guildford, England (1980), College Park, Maryland (1985), Tucson, Arizona (1990), and Munich, Germany (1995). Among the results were a series of reports listed below, as well as the book for which this serves as the Preface. * Jollow, DJ., Kocsis, J.J., Snyder, R. and Vainio, H. (eds), Biological Reactive Intermediates: Formation, Toxicity and Inactivation, Plenum Press, NY, 1975. * Snyder, R., Park, D.V., Kocsis, J.J., Jollow, D.V., Gibson, G.G. and Witmer, C.M. (eds), Biological Reactive Intermediates II: Chemical Mechanisms and Biological Effects, Plenum Press, N.Y., 1982.

Free Delivery
Pinterest Twitter Facebook Google+
You may like...
Art and Challenges Involved in the…
Nieves Saiz-Sapena, Fernando Aparici-Robles, … Hardcover R2,810 Discovery Miles 28 100
Eight Days In July - Inside The Zuma…
Qaanitah Hunter, Kaveel Singh, … Paperback  (1)
R360 R337 Discovery Miles 3 370
Vector Calculus - 3rd Edition
Alice Gorguis Hardcover R736 Discovery Miles 7 360
Bahamas in World War II - A Military…
Eric Wiberg Hardcover R1,780 Discovery Miles 17 800
Madam & Eve 2018 - The Guptas Ate My…
Stephen Francis, Rico Schacherl Paperback R220 R203 Discovery Miles 2 030
Iron In The Soul - The Leaders Of The…
F. A. Mouton Paperback  (1)
R108 Discovery Miles 1 080
Haas Das Se Nuuskas: Episode 5
Louise Smit Paperback R195 R183 Discovery Miles 1 830
Light Through The Bars - Understanding…
Babychan Arackathara Paperback R30 R28 Discovery Miles 280
Medieval Fabrications - Dress, Textiles…
E. Burns Hardcover R2,886 Discovery Miles 28 860
Unison Soft Pastels (Heather Harman Set…
R5,618 R4,700 Discovery Miles 47 000

 

Partners