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Biological Reactive Intermediates Vi - Chemical and Biological Mechanisms in Susceptibility to and Prevention of Environmental Diseases (Hardcover, 2001 ed.)
Loot Price: R5,656
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Biological Reactive Intermediates Vi - Chemical and Biological Mechanisms in Susceptibility to and Prevention of Environmental Diseases (Hardcover, 2001 ed.)
Series: Advances in Experimental Medicine and Biology, 500
Expected to ship within 10 - 15 working days
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Historically we have separated the disciplines of Chemistry and
Biochemistry by recognizing that the distinguishing characteristic
of Biochemistry is the catalysis of reactions by enzymes. Enzymes
permit metabolic reactions which would otherwise require extremes
of temperature, pressure or pH, often associated with Chemistry, to
proceed under ambient conditions of the body. Under some conditions
chemical reactions occur in vivo in which products of enzymatic
reactions proceed to undergo further reactions non- enzymatically
with cellular macromolecules. The results can often be seen as
toxic or carcinogenic responses. The chemicals that initiate these
reactions are termed "biological reactive intermediates. " The
International Symposia on Biological Reactive Intermediates (BRI)
began in 1975 at the University of Turku, Finland and have since
convened at the University of Surrey, Guildford, The United Kingdom
(1980), the University of Maryland, College Park, Maryland (1985),
the University of Arizona, Tucson, Arizona (1990), the GSF
Forschungszentrum and Technical University of Munich (1995) and,
most recently, at the Universite Rene Descartes, Paris, France
(2000). The Symposium was organized by an International Planning
Committee co-chaired by P. Dansette (Paris, France) and TJ. Monks
(Austin, Texas). The committee included: P. H. Beaune (Paris,
France), M. De\aforge (Saclay, France), G. P. Gervasi (Pisa,
Italy), G. G. Gibson (Guildford, UK), H. Greim (Munich, Germany),
DJ. Jollow (Charleston, South Carolina), P. Moldeus (Sodertalje,
Sweden), I. G. Sipes (Tucson, Arizona), R. Snyder PJ. van Bladderen
(Zeist, The Netherlands). They were (Piscataway, New Jersey), and
assisted by an International Scientific Program Advisory Committee
which included: TJ.
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