This book deals with the remarkable life of a powerful and fiery woman at the heart of the turbulent Barons' Wars. As sister of Henry III and aunt of the future Edward I, Eleanor de Montfort was at the heart of the bloody conflict between the Crown and the English barons. At Lewes in 1264 Simon de Montfort captured the king and secured control of royal government. A woman of fiery nature, Eleanor worked tirelessly in supporting her husband's cause. She assumed responsibility for the care of the royal prisoners and she regularly dispatched luxurious gifts to Henry III and the Lord Edward. But the family's political fortunes were shattered at the battle of Evesham in August 1265 where Simon de Montfort was killed. The newly-widowed Eleanor rose to her role as matriarch of her family, sending her surviving sons - and the family treasure - overseas to France, negotiating the surrender of Dover Castle and securing her own safe departure from the realm. The last ten years of her life were spent in the Dominican convent at Montargis. Drawing on chronicles, letters and public records this book reconstructs the narrative of Eleanor's remarkable life.

Papers on aspects of the growth of royal government during the century. The size and jurisdiction of English royal government underwent sustained development in the thirteenth century, an understanding of which is crucial to a balanced view of medieval English society. The papers here follow three central themes: the development of central government, law and justice, and the crown and the localities. Examined within this framework are bureaucracy and enrolment under John and his contemporaries; the Royal Chancery; the adaptation of the Exchequer in response to the rapidly changing demands of the crown; the introduction of a licensing system for mortmain alienations; the administration of local justice; women as sheriffs; and a Nottinghamshire study examining the tensions between the role of the king as manorial lord and as monarch. Contributors: NICK BARRATT, PAUL R. BRAND, DAVID CARPENTER, DAVID CROOK, ANTHONY MUSSON, NICHOLAS C. VINCENT, LOUISE WILKINSON

This book explores the interplay and dialogue between faith communities and the humanitarian-development community. Faith and religion are key influencers of thought and practice in many communities around the world and development practitioners would not be able to change behaviours for improved health and social relations without the understanding and influence of those with authority in communities, such as religious leaders. Equally, religious leaders feel responsibilities to their communities, but do not necessarily have the technical knowledge and resources at hand to provide the information or services needed to promote the well-being of all in their scope of influence. The book demonstrates that partnerships between humanitarian-development practitioners and religious communities can be mutually beneficial exchanges, but that there are also frequently pitfalls along the way and opportunities for lessons to be learned by each party. Delving into how humanitarians and faith communities engage with one another, the book focuses on building knowledge about how they interact as peers with different yet complementary roles in community development. The authors draw on the Channels of Hope methodology, a tool which seeks to engage faith leaders in addressing social norms and enact social change, as well as other related research in the sector to demonstrate the many ways in which humanitarian and development policy makers and practitioners could achieve more systematic engagement with faith groups. This book is an important contribution to the growing body of literature on faith and development, and will be useful both to researchers, and to practitioners working with faith communities.

This book investigates the ways in which the humanitarian system is secular and understands religious beliefs and practices when responding to disasters. The book teases out the reasons why humanitarians are reluctant to engage with what are seen as "messy" cultural dynamics within the communities they work with, and how this can lead to strained or broken relationships with disaster-affected populations and irrelevant and inappropriate disaster assistance that imposes distant and relatively meaningless values. In order to interrogate secular boundaries within humanitarian response, the book draws particularly on qualitative primary data from the aftermath of Typhoon Haiyan in the Philippines. The case study shows how religious practices and beliefs strongly influenced people's disaster experience, yet humanitarian organisations often failed to recognise or engage with this. Whilst secularity in the humanitarian system does not completely exclude religious participation and expression, it does create biases and boundaries. Many humanitarians view their secularity as essential to their position of impartiality and cultural sensitivity in comparison to what were seen as the biased and unprofessional beliefs and practices of religions and religious actors, even though disaster-affected people felt that it was the secular humanitarians that were less impartial and culturally sensitive. This empirically driven examination of the role of secularity within humanitarianism will be of interest to the growing field of "pracademic" researchers across NGOs, government, consultancy, and think tanks, as well as researchers working directly within academic institutions.

Since the first edition of Stochastic Modelling for Systems Biology, there have been many interesting developments in the use of "likelihood-free" methods of Bayesian inference for complex stochastic models. Having been thoroughly updated to reflect this, this third edition covers everything necessary for a good appreciation of stochastic kinetic modelling of biological networks in the systems biology context. New methods and applications are included in the book, and the use of R for practical illustration of the algorithms has been greatly extended. There is a brand new chapter on spatially extended systems, and the statistical inference chapter has also been extended with new methods, including approximate Bayesian computation (ABC). Stochastic Modelling for Systems Biology, Third Edition is now supplemented by an additional software library, written in Scala, described in a new appendix to the book. New in the Third Edition New chapter on spatially extended systems, covering the spatial Gillespie algorithm for reaction diffusion master equation models in 1- and 2-d, along with fast approximations based on the spatial chemical Langevin equation Significantly expanded chapter on inference for stochastic kinetic models from data, covering ABC, including ABC-SMC Updated R package, including code relating to all of the new material New R package for parsing SBML models into simulatable stochastic Petri net models New open-source software library, written in Scala, replicating most of the functionality of the R packages in a fast, compiled, strongly typed, functional language Keeping with the spirit of earlier editions, all of the new theory is presented in a very informal and intuitive manner, keeping the text as accessible as possible to the widest possible readership. An effective introduction to the area of stochastic modelling in computational systems biology, this new edition adds additional detail and computational methods that will provide a stronger foundation for the development of more advanced courses in stochastic biological modelling.

This book investigates the ways in which the humanitarian system is secular and understands religious beliefs and practices when responding to disasters. The book teases out the reasons why humanitarians are reluctant to engage with what are seen as "messy" cultural dynamics within the communities they work with, and how this can lead to strained or broken relationships with disaster-affected populations and irrelevant and inappropriate disaster assistance that imposes distant and relatively meaningless values. In order to interrogate secular boundaries within humanitarian response, the book draws particularly on qualitative primary data from the aftermath of Typhoon Haiyan in the Philippines. The case study shows how religious practices and beliefs strongly influenced people's disaster experience, yet humanitarian organisations often failed to recognise or engage with this. Whilst secularity in the humanitarian system does not completely exclude religious participation and expression, it does create biases and boundaries. Many humanitarians view their secularity as essential to their position of impartiality and cultural sensitivity in comparison to what were seen as the biased and unprofessional beliefs and practices of religions and religious actors, even though disaster-affected people felt that it was the secular humanitarians that were less impartial and culturally sensitive. This empirically driven examination of the role of secularity within humanitarianism will be of interest to the growing field of "pracademic" researchers across NGOs, government, consultancy, and think tanks, as well as researchers working directly within academic institutions.

ISBN 978-0-573-69927-6

Anthony J. Wilkinson
Original Music composed by David Boyd

Comedy

Characters: 10 male, 6 female

Andrew and Anthony are getting married - and everyone wants to "help" My Big Gay Italian Wedding spins into a hysterical fiasco as everyone tries to have their way. From a saboteur ex-boyfriend to a loud, opinionated, outspoken Italian mother, personalities and culture collide in a music and dance-filled extravaganza.

"Feel-good hysterical comedy " -The Wall Street Journal.

"Hysterically funny Everyone is going to have his or her favorite moment in My Big Gay Italian Wedding, the insanely funny and fun confection. The mixture of the sacred and profane, the ultra-serious and ultra-silly makes this the perfect play." -Edge New York.

"Genuinely entertaining " -New York Times.

After Anthony's father passes away, old family members are reunited after not having been on the best of terms for over a decade. This is a hilarious take on all of the fun characters that show up at a funeral home. This is a sequel to Anthony J. Wilkinson's 'My Big Gay Italian Wedding, ' and including some of the same characters

Since the first edition of Stochastic Modelling for Systems Biology, there have been many interesting developments in the use of "likelihood-free" methods of Bayesian inference for complex stochastic models. Having been thoroughly updated to reflect this, this third edition covers everything necessary for a good appreciation of stochastic kinetic modelling of biological networks in the systems biology context. New methods and applications are included in the book, and the use of R for practical illustration of the algorithms has been greatly extended. There is a brand new chapter on spatially extended systems, and the statistical inference chapter has also been extended with new methods, including approximate Bayesian computation (ABC). Stochastic Modelling for Systems Biology, Third Edition is now supplemented by an additional software library, written in Scala, described in a new appendix to the book. New in the Third Edition New chapter on spatially extended systems, covering the spatial Gillespie algorithm for reaction diffusion master equation models in 1- and 2-d, along with fast approximations based on the spatial chemical Langevin equation Significantly expanded chapter on inference for stochastic kinetic models from data, covering ABC, including ABC-SMC Updated R package, including code relating to all of the new material New R package for parsing SBML models into simulatable stochastic Petri net models New open-source software library, written in Scala, replicating most of the functionality of the R packages in a fast, compiled, strongly typed, functional language Keeping with the spirit of earlier editions, all of the new theory is presented in a very informal and intuitive manner, keeping the text as accessible as possible to the widest possible readership. An effective introduction to the area of stochastic modelling in computational systems biology, this new edition adds additional detail and computational methods that will provide a stronger foundation for the development of more advanced courses in stochastic biological modelling.

The true importance of cathedrals during the Anglo-Norman period is here brought out, through an examination of the most important aspects of their history. Cathedrals dominated the ecclesiastical (and physical) landscape of the British Isles and Normandy in the middle ages; yet, in comparison with the history of monasteries, theirs has received significantly less attention. This volume helps to redress the balance by examining major themes in their development between the eleventh and thirteenth centuries. These include the composition, life, corporate identity and memory of cathedral communities; the relationships, sometimes supportive, sometimes conflicting, that they had with kings (e.g. King John), aristocracies, and neighbouring urban and religious communities; the importance of cathedrals as centres of lordship and patronage; their role in promoting and utilizing saints' cults (e.g. that of St Thomas Becket); episcopal relations; and the involvement of cathedrals in religious and political conflicts, and in the settlement of disputes. A critical introduction locates medieval cathedrals in space and time, and against a backdrop of wider ecclesiastical change in the period. Contributors: Paul Dalton, Charles Insley, Louise J. Wilkinson, Ann Williams, C.P. Lewis, RichardAllen, John Reuben Davies, Thomas Roche, Stephen Marritt, Michael Staunton, Sheila Sweetinburgh, Paul Webster, Nicholas Vincent

A detailed investigation of the place of women in thirteenth-century society, using individual case studies to reappraise orthodox opinion. This book offers the first regional study of women in thirteenth-century England, making pioneering use of charters, chronicles, government records and some of the earliest manorial court rolls to examine the interaction of gender, status and life-cycle in shaping women's experiences in Lincolnshire. The author investigates the lives of noblewomen, gentlewomen, townswomen, peasant women, criminal women and women religious from a variety of angles. Not onlydoes she consider how far women were partners alongside men, especially within the family, but she also explores whether they might have been both at once constrained and yet, to an extent, empowered by religious and biological ideas about gender difference which found expression in inheritance practices and the common law. Valuable light on the avenues for political influence open to elite women is shed through case studies of Nicholaa de la Haye (d. 1230), sheriff of Lincoln, Hawise de Quency (d. 1243), countess of Lincoln, and Margaret de Lacy (d. 1266), countess of Lincoln. The book also addresses women's roles within the rural and urban labour markets before the Black Death. LOUISE J. WILKINSON is Professor of Medieval Studies, University of Lincoln.

A survey of the complexity and sophistication of English royal government in the thirteenth century, a period of radical change. The years between 1258 and 1276 comprise one of the most influential periods in the Middle Ages in Britain. This turbulent decade witnessed a bitter power struggle between Henry III and his barons over who should control the government of the realm. Before England eventually descended into civil war, a significant proportion of the baronage had attempted to transform its governance by imposing on the crown a programme of legislative and administrative reform far more radical and wide-ranging than Magna Carta in 1215. Constituting a critical stage in the development of parliament, the reformist movement would remain unsurpassed in its radicalism until the upheavals of the seventeenth century. Simon de Montfort, the baronial champion, became the first leader of a political movement to seize power and govern in the king's name. The essays here draw on material available for the first time via the completion of the project to calendar all the Fine Rolls of Henry III; these rolls comprise the last series of records of the English Chancery from that period to become readily available in a convenient form, thereby transforming accessto several important fields of research, including financial, legal, political and social issues. The volume covers topics including the evidential value of the fine rolls themselves and their wider significance for the English polity, developments in legal and financial administration, the roles of women and the church, and the fascinating details of the development of the office of escheator. Related or parallel developments in Scotland, Wales and Ireland are also dealt with, giving a broader British dimension. LOUISE J. WILKINSON is Professor of Medieval Studies, University of Lincoln; DAVID CROOK is Honorary Research Fellow at the University of Notthingham. Contributors: Nick Barratt, Paul Brand, David Carpenter, David Crook, Paul Dryburgh, Beth Hartland, Philippa Hoskin, Charles Insley, Adrian Jobson, Tony Moore, Alice Taylor, Nicholas Vincent, Scott Waugh, Louise Wilkinson

A survey of the complexity and sophistication of English royal government in the thirteenth century, a period of radical change. The years between 1258 and 1276 comprise one of the most influential periods in the Middle Ages in Britain. This turbulent decade witnessed a bitter power struggle between Henry III and his barons over who should control the government of the realm. Before England eventually descended into civil war, a significant proportion of the baronage had attempted to transform its governance by imposing on the crown a programme of legislative and administrative reform far more radical and wide-ranging than Magna Carta in 1215. Constituting a critical stage in the development of parliament, the reformist movement would remain unsurpassed in its radicalism until the upheavals of the seventeenth century. Simon de Montfort, the baronial champion, became the first leader of a political movement to seize power and govern in the king's name. The essays here draw on material available for the first time via the completion of the project to calendar all the Fine Rolls of Henry III; these rolls comprise the last series of records of the English Chancery from that period to become readily available in a convenient form, thereby transforming accessto several important fields of research, including financial, legal, political and social issues. The volume covers topics including the evidential value of the fine rolls themselves and their wider significance for the English polity, developments in legal and financial administration, the roles of women and the church, and the fascinating details of the development of the office of escheator. Related or parallel developments in Scotland, Wales and Ireland are also dealt with, giving a broader British dimension.

Exciting fresh perspectives on Edward I as man, king and administrator. The reign of Edward I was one of the most important of medieval England, but the king's activities and achievements have not always received the full attention they deserve. The essays collected here offer fresh insights into Edward's own personality as well as developments in law, governance, war and culture. Edward the man emerges in chapters on his early life, his piety and his family, while the administrator king is discussed in evaluations of his twogreat ministers, his handling of the crucial issue of law and order and the way he managed the realm from abroad through his correspondence. Edward's nobles, both in England and Scotland, naturally appear as vital to understanding the reign, while his rule is set in a British and European context. Overall, the book aims to move the debate on the reign beyond K.B. McFarlane's hugely influential judgement that "Edward I preferred masterfulness to the arts of political management", by highlighting his skills -- and failings -- as a politician and manager.

American business is dysfunctional. Companies of all sizes follow the mistaken belief that their products and services are best sold through mega-customers with pervasive market reach, such as Amazon and Walmart. Far too many business leaders fail to realize-until it is too late-that the relentless pursuit of volume at all cost is not the key to long-term profits and success. The Customer Trap: How to Avoid the Biggest Mistake in Business is Thomas and Wilkinson's sequel to The Distribution Trap: Keeping Your Innovations from Becoming Commodities, which won the Berry-American Marketing Association Prize for the best marketing book of 2010. The Distribution Trap contended that cracking the big-box channel is not necessarily the Holy Grail that many marketers assume it is. The Customer Trap takes this thesis to the next level by arguing that all companies, regardless of the industry there are in, should maintain control over their sales and distribution channels. Volume forgone by avoiding the mass market is more than offset by higher margins and stronger brand equity. The Customer Trap shows that giving power to a customer who violates "the ten percent rule" sets a company up for ruin. Yet, when presented with the opportunity to push more sales through large customers, most decision-makers jump at the chance. As a result, marketing has come to resemble a relentless quest for efficiency and scale. Demands from mega-customers in the form of discounts, deals, and incentives erode the integrity of the brand and what it originally stood for. Lower margins become the norm and cost-saving compromises on quality take over. In time, the brand suffers and, in some cases, fails outright. Stark examples from Oreck Vacuum Cleaners, Rubbermaid, Goodyear, Levi's, and others illustrate the perils of falling into the "customer trap." This book demonstrates in vivid detail how to thrive by controlling your sales and distribution. The authors show how many firms, such as STIHL Inc., etailz, Apple, Red Ant Pants, and Columbia Paints & Coatings, have prospered by avoiding the "customer trap"-and how your company can have similar success.

This book explores the interplay and dialogue between faith communities and the humanitarian-development community. Faith and religion are key influencers of thought and practice in many communities around the world and development practitioners would not be able to change behaviours for improved health and social relations without the understanding and influence of those with authority in communities, such as religious leaders. Equally, religious leaders feel responsibilities to their communities, but do not necessarily have the technical knowledge and resources at hand to provide the information or services needed to promote the well-being of all in their scope of influence. The book demonstrates that partnerships between humanitarian-development practitioners and religious communities can be mutually beneficial exchanges, but that there are also frequently pitfalls along the way and opportunities for lessons to be learned by each party. Delving into how humanitarians and faith communities engage with one another, the book focuses on building knowledge about how they interact as peers with different yet complementary roles in community development. The authors draw on the Channels of Hope methodology, a tool which seeks to engage faith leaders in addressing social norms and enact social change, as well as other related research in the sector to demonstrate the many ways in which humanitarian and development policy makers and practitioners could achieve more systematic engagement with faith groups. This book is an important contribution to the growing body of literature on faith and development, and will be useful both to researchers, and to practitioners working with faith communities.

This book discusses all aspects of non-pharmacologic approaches to primary and secondary CVD prevention. It highlights the strength of evidence for particular diet styles in CVD prevention, including plant-based diets, the Mediterranean diet, the DASH diet, and low-carbohydrate diets. Chapters present evidence and future directions for diet and nutrition in diseases related to CVD, such as dyslipidemia, cardiometabolic disease (pre-diabetes, the metabolic syndrome, type-2 diabetes mellitus), and obesity. Finally, the book reviews novel and emerging aspects of dietary intervention in CVD prevention, such as dietary approaches to inflammation and the role of the microbiome in CVD. Up-to-date, evidence-based, and clinically oriented, Prevention and Treatment of Cardiovascular Disease: Nutritional and Dietary Approaches is an essential resource for physicians, residents, fellows, and medical students in cardiology, clinical nutrition, family medicine, endocrinology, and lipidology.

A detailed investigation of the place of women in thirteenth-century society, using individual case studies to reappraise orthodox opinion. This book offers the first regional study of women in thirteenth-century England, making pioneering use of charters, chronicles, government records and some of the earliest manorial court rolls to examine the interaction of gender, status and life-cycle in shaping women's experiences in Lincolnshire. The author investigates the lives of noblewomen, gentlewomen, townswomen, peasant women, criminal women and women religious from a variety of angles. Not onlydoes she consider how far women were partners alongside men, especially within the family, but she also explores whether they might have been both at once constrained and yet, to an extent, empowered by religious and biological ideas about gender difference which found expression in inheritance practices and the common law. Valuable light on the avenues for political influence open to elite women is shed through case studies of Nicholaa de la Haye (d. 1230), sheriff of Lincoln, Hawise de Quency (d. 1243), countess of Lincoln, and Margaret de Lacy (d. 1266), countess of Lincoln. The book also addresses women's roles within the rural and urban labour markets before the Black Death. LOUISE J. WILKINSON is Professor of Medieval Studies, University of Lincoln,

Edition with English translation of a document shedding huge light on one of the most important figures of her time. The household roll of Eleanor, countess of Leicester and Pembroke, offers a fascinating insight into one of the most important domestic establishments in England during the Second Barons' War of 1263-7. As the wife of Simon de Montfort, earl of Leicester, the leading figure within the baronial regime, and the sister and aunt of King Henry III and the Lord Edward, respectively, Countess Eleanor occupied a position at the heart of English political affairs up to, and after, her husband's death at the Battle of Evesham on 4 August 1265. This volume is a critical edition of the extant thirteen membranes of Countess Eleanor's household account roll for that momentous year, 1265 (British Library, Additional MS 8877). Presented here in the original Latin and with an accompanying English translation, Countess Eleanor's roll includes her diet account for the period from 19 February to 29 August 1265, listing her visitors and the different items of food and drink consumed on each day at each castle at which she was resident, including Wallingford, Odiham and Dover. The roll also incorporates a "wardrobe journal", covering the period up until 1 October 1265, detailing expenditure on the purchase and repair of household furnishings, goods and utensils, on clothing and wages, on the Montfortian war effort in the South, and on messengers travelling to and from the countess, Earl Simon, her sons and associates, in the months before and after the Battle of Evesham.

Designed for quick, easy reference in the office or clinic, Atlas of Vulvar Disease is a robust pictorial and textual guide to the diagnosis, treatment, and management of vulvar diseases. Written by Edward J. Wilkinson, MD, a professor of pathology and expert in gynecologic pathology, and I. Keith Stone, MD, a professor of obstetrics and gynecology, this atlas is a must-have resource for both clinicians and pathologists focused on women's health. Organized by dermatologic findings, Atlas of Vulvar Disease presents a complete overview of diseases within each broader topic area. Each disorder includes a definition, general features, clinical presentation, microscopic features, differential diagnosis, clinical behavior and treatment, and progressive therapeutic options, to guide the diagnosis and treatment of various vulvar diseases. Hundreds of full-color clinical photographs and relevant histopathologic photographs illustrate the clinical appearance and histopathologic characteristics of the full spectrum of vulvar diseases. Tables on sexually transmitted diseases, vesicobullous disease, and the classification of vulvar diseases are included to assist in differential diagnosis. Clinical pathological correlations aid in the diagnosis and interpretation of laboratory findings. Two indexes facilitate quick look up a disease entity or a clinical presentation. A free companion web site features the full-text as well as an extensive image bank of clinical and histopathologic photographs from the book.

This book discusses all aspects of non-pharmacologic approaches to primary and secondary CVD prevention. It highlights the strength of evidence for particular diet styles in CVD prevention, including plant-based diets, the Mediterranean diet, the DASH diet, and low-carbohydrate diets. Chapters present evidence and future directions for diet and nutrition in diseases related to CVD, such as dyslipidemia, cardiometabolic disease (pre-diabetes, the metabolic syndrome, type-2 diabetes mellitus), and obesity. Finally, the book reviews novel and emerging aspects of dietary intervention in CVD prevention, such as dietary approaches to inflammation and the role of the microbiome in CVD. Up-to-date, evidence-based, and clinically oriented, Prevention and Treatment of Cardiovascular Disease: Nutritional and Dietary Approaches is an essential resource for physicians, residents, fellows, and medical students in cardiology, clinical nutrition, family medicine, endocrinology, and lipidology.