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On starting to write the preface it occured to the editors that it
might be a good idea to incorporate so me organizational thoughts.
First of all, why have. we organized this book on "Glycoprotein
storage diseases", an unfamiliar area of pathology unlikely to be
encountered in practice? In preparing such a volume we considered
that in the past ten years there has been a large amount of
intensive research activity on glycoproteinoses and no detailed
review has been entirely devoted to this subject. This research has
led to new information about hereditary mental retardation and
progressive neurologie degeneration, and as clinicians we are
impressed with its clinical importance. This volume is intended to
represent for the uninitiated as weH as for the expert a summary of
studies on dis orders of glycoprotein catabolism written by experts
in each area. Each author has written with freedom about his
particular experience, describing the establishment and development
of his investigations, his methods, the utility and limitations of
his work and eventual sources of problems. We are grateful for
their many fundamental studies and for their having generously
accepted to partecipate in this book. The Editors Acknowledgements
We wish to express our gratitude to our friends and colleagues G.
Romeo, W.S. Sly and G. Tettamanti whose criticism and suggestions
have significantly improved the quality of particular chapters or
sections.
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