With the decade-long desire for optimum performance using biomaterials without additional surgery, replacement or maintenance, a desperate search is underway for tailoring the physical and physico-chemical properties of the materials surface and the biosystem.
This is the first book to concentrate on the highly important area of metal-based implants and their improved functionality and acceptance by the body. It thus focuses on the properties of biomaterial-tissue interfaces, which are discussed in terms of the biomaterials and the specific biological environments they are used in. Strong emphasis is placed on the recent results and success in improving the interface characterization towards implant refinement.
From the contents:
I. Interface Influence of Materials and Surface Modifications
* Passivity-inducing and -retaining Surfaces
* Topological Surface Modifications
* Chemical Surface Modifications
II. Physical and Physicochemical Surface Characterization
* Surface Topology
* Electrochemical Characterization
* Spectroscopic Interface Characterization
* Physical Characterization of Protein Adsorption
III. Biological Characterization of the Interface and Materials Related Biosystem Reactions
* Protein and Cell Adhesion Mechanisms
* Material-induced Cell Interactions
* Topology-dependent Cellular Interactions
* Materials-dependent Formation of New Hard Tissue