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Pathogenesis of Mycobacterium tuberculosis and its Interaction with the Host Organism (Hardcover, 2013 ed.): Jean Pieters, John... Pathogenesis of Mycobacterium tuberculosis and its Interaction with the Host Organism (Hardcover, 2013 ed.)
Jean Pieters, John D Mc Kinney
R5,283 R4,936 Discovery Miles 49 360 Save R347 (7%) Ships in 12 - 19 working days

"Mycobacterium tuberculosis" is one of the most notorious pathogens on earth, causing the death of approximately 1.5 million people annually. A major problem in the fight against tuberculosis is the emergence of strains that have acquired resistance to all available antibiotics. One key to the success of "M. tuberculosis" as a pathogen is its ability to circumvent host immune responses at different levels. This is not only a result of the special makeup of "M. tuberculosis" in terms of genetic diversity and DNA metabolism and its possession of specialized secretion systems, but also of its ability to hijack the host s innate immune defence mechanisms.

In this volume, researchers from different disciplines provide a topical overview of the diverse mechanisms that contribute to the virulence of "M. tuberculosis," ranging from their genetic, metabolic and molecular makeup, as well as the complex strategies these bacteria utilize to escape immune destruction within infected hosts."

Pathogenesis of Mycobacterium tuberculosis and its Interaction with the Host Organism (Paperback, Softcover reprint of the... Pathogenesis of Mycobacterium tuberculosis and its Interaction with the Host Organism (Paperback, Softcover reprint of the original 1st ed. 2013)
Jean Pieters, John D Mc Kinney
R5,031 Discovery Miles 50 310 Ships in 10 - 15 working days

Mycobacterium tuberculosis is one of the most notorious pathogens on earth, causing the death of approximately 1.5 million people annually. A major problem in the fight against tuberculosis is the emergence of strains that have acquired resistance to all available antibiotics. One key to the success of M. tuberculosis as a pathogen is its ability to circumvent host immune responses at different levels. This is not only a result of the special makeup of M. tuberculosis in terms of genetic diversity and DNA metabolism and its possession of specialized secretion systems, but also of its ability to hijack the host's innate immune defence mechanisms. In this volume, researchers from different disciplines provide a topical overview of the diverse mechanisms that contribute to the virulence of M. tuberculosis, ranging from their genetic, metabolic and molecular makeup, as well as the complex strategies these bacteria utilize to escape immune destruction within infected hosts.

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