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Applications of Chimeric Genes and Hybrid Proteins, Part B: Cell Biology and Physiology, Volume 327 (Hardcover): Melvin I. Simon Applications of Chimeric Genes and Hybrid Proteins, Part B: Cell Biology and Physiology, Volume 327 (Hardcover)
Melvin I. Simon; Volume editing by Jeremy Thorner, Scott D. Emr, John N. Abelson
R4,508 Discovery Miles 45 080 Ships in 12 - 19 working days

The critically acclaimed laboratory standard for more than forty years, Methods in Enzymology is one of the most highly respected publications in the field of biochemistry. Since 1955, each volume has been eagerly awaited, frequently consulted, and praised by researchers and reviewers alike. Now with more than 300 volumes (all of them still in print), the series contains much material still relevant today--truly an essential publication for researchers in all fields of life sciences.

Numerical Computer Methods, Part C, Volume 321 (Hardcover): John N. Abelson, Melvin I. Simon Numerical Computer Methods, Part C, Volume 321 (Hardcover)
John N. Abelson, Melvin I. Simon; Volume editing by Michael L. Johnson, Ludwig Brand
R6,164 R5,161 Discovery Miles 51 610 Save R1,003 (16%) Ships in 12 - 19 working days

The critically acclaimed laboratory standard for more than forty years, Methods in Enzymology is one of the most highly respected publications in the field of biochemistry. Since 1955, each volume has been eagerly awaited, frequently consulted, and praised by researchers and reviewers alike. Now with more than 300 volumes (all of them still in print), the series contains much material still relevant today--truly an essential publication for researchers in all fields of life sciences.

Ghrelin, Volume 514 (Hardcover): John N. Abelson, Kenji Kangawa Ghrelin, Volume 514 (Hardcover)
John N. Abelson, Kenji Kangawa
R4,585 Discovery Miles 45 850 Ships in 12 - 19 working days

This new volume of "Methods in Enzymology" continues the legacy of this premier serial by containing quality chapters authored by leaders in the field. The volumecovers ghrelin, andhas chapters on such topics as orphan gpcrs and methods for identifying their ligands, ghrelin o-acyltransferase assays and inhibition, and thermogenic characterization of ghrelin receptor null mice.
Contains quality chapters authored by leaders in the field Has chapters on such topics as orphan gpcrs and methods for identifying their ligands, ghrelin o-acyltransferase assays and inhibition, and thermogenic characterization of ghrelin receptor null mice"

Non-Natural Amino Acids, Volume 462 (Hardcover): Tom W. Muir, John N. Abelson Non-Natural Amino Acids, Volume 462 (Hardcover)
Tom W. Muir, John N. Abelson
R4,794 Discovery Miles 47 940 Ships in 12 - 19 working days

By combining the tools of organic chemistry with those of physical biochemistry and cell biology, "Non-Natural Amino" "Acids" aims to provide fundamental insights into how proteins work within the context of complex biological systems of biomedical interest.
The critically acclaimed laboratory standard for 40 years, "Methods in Enzymology" is one of the most highly respected publications in the field of biochemistry. Since 1955, each volume has been eagerly awaited, frequently consulted, and praised by researchers and reviewers alike. With more than 400 volumes published, each "Methods in Enzymology" volume presents material that is relevant in today's labs -- truly an essential publication for researchers in all fields of life sciences.
Demonstrates how the tools and principles of chemistry combined with the molecules and processes of living cells can be combined to create molecules with new properties and functions found neither in nature nor in the test tube
Presents new insights into the molecular mechanisms of complex biological and chemical systems that can be gained by studying the structure and function of non-natural molecules
Provides a "one-stop shop" for tried and tested essential techniques, eliminating the need to wade through untested or unreliable methods

Antisense Technology, Part A, General Methods, Methods of Delivery, and RNA Studies, Volume 313 (Hardcover): John N. Abelson,... Antisense Technology, Part A, General Methods, Methods of Delivery, and RNA Studies, Volume 313 (Hardcover)
John N. Abelson, Melvin I. Simon; Volume editing by M.Ian Phillips
R4,333 Discovery Miles 43 330 Ships in 12 - 19 working days

Antisense technology is the ability to manipulate gene expression within mammalian cells providing powerful experimental approaches for the study of gene function and gene regulation. For example, methods that inhibit gene expression permit studies which probe the normal function of a specific product within a cell. Such methodology can be used in many disciplines such as pharmacology, oncology, genetics, cell biology, developmental biology, molecular biology, biochemistry, and neurosciences. This volume will be a truly important tool in biomedical-oriented research.
The critically acclaimed laboratory standard for more than forty years, Methods in Enzymology is one of the most highly respected publications in the field of biochemistry. Since 1955, each volume has been eagerly awaited, frequently consulted, and praised by researchers and reviewers alike. Now with more than 300 volumes (all of them still in print), the series contains much material still relevant today--truly an essential publication for researchers in all fields of life sciences.

Confocal Microscopy, Volume 307 (Hardcover): John N. Abelson, Melvin I. Simon Confocal Microscopy, Volume 307 (Hardcover)
John N. Abelson, Melvin I. Simon; Volume editing by P.Michael Conn
R4,832 Discovery Miles 48 320 Ships in 12 - 19 working days

This volume supplements Volumes 63, 64, 87, and 249 of Methods in Enzymology. These volumes provide a basic source for the quantitative interpretation of enzyme rate data and the analysis of enzyme catalysis. Among the major topics covered are Engergetic Coupling in Enzymatic Reactions, Intermediates and Complexes in Catalysis, Detection and Properties of Low Barrier Hydrogen Bonds, Transition State Determination, and Inhibitors.
The critically acclaimed laboratory standard for more than forty years, Methods in Enzymology is one of the most highly respected publications in the field of biochemistry. Since 1955, each volume has been eagerly awaited, frequently consulted, and praised by researchers and reviewers alike. Now with more than 300 volumes (all of them still in print), the series contains much material still relevant today--truly an essential publication for researchers in all fields of life sciences.

ABC Transporters: Biochemical, Cellular, and Molecular Aspects, Volume 292 (Hardcover): John N. Abelson, Melvin I. Simon ABC Transporters: Biochemical, Cellular, and Molecular Aspects, Volume 292 (Hardcover)
John N. Abelson, Melvin I. Simon; Volume editing by Suresh V. Ambudkar, Michael M. Gottesman
R4,368 Discovery Miles 43 680 Ships in 12 - 19 working days

The critically acclaimed laboratory standard for more than forty years, Methods in Enzymology is one of the most highly respected publications in the field of biochemistry. Since 1955, each volume has been eagerly awaited, frequently consulted, and praised by researchers and reviewers alike. More than 285 volumes have been published (all of them still in print) and much of the material is relevant even today-truly an essential publication for researchersin all fields of life sciences.
Key Features
* Prokaryotic ABC Transporters
* Eukaryotic ABC Transporters
* Nonmammalian ABC Transport Systems
* Mammalian P-Glycoproteins
* Multidrug Resistance Associated Protein
* Cystic Fibrosis Transmembrane Conductance Regulator
* Sulfonylurea Receptor
* Intracellular ABC Transporters

High Resolution Separation and Analysis of Biological Macromolecules, Part B: Applications, Volume 271 (Hardcover): John N.... High Resolution Separation and Analysis of Biological Macromolecules, Part B: Applications, Volume 271 (Hardcover)
John N. Abelson, Melvin I. Simon; Volume editing by Barry L. Karger, William Hancock
R4,047 Discovery Miles 40 470 Ships in 12 - 19 working days

The critically acclaimed laboratory standard for more than forty years, Methods in Enzymology is one of the most highly respected publications in the field of biochemistry. Since 1955, each volume has been eagerly awaited, frequently consulted, and praised by researchers and reviewers alike. More than 260 volumes have been published (all of them still in print) and much of the material is relevant even today--truly an essential publication for researchers in all fields of life sciences.
Key Features
* Liquid chromatography
* Electrophoresis
* Mass spectrometry

Molecular Design and Modeling: Concepts and Applications, Part A: Proteins, Peptides, and Enzymes, Volume 202 (Hardcover): John... Molecular Design and Modeling: Concepts and Applications, Part A: Proteins, Peptides, and Enzymes, Volume 202 (Hardcover)
John N. Abelson, Melvin I. Simon; Volume editing by John J. Langone
R1,594 Discovery Miles 15 940 Ships in 12 - 19 working days

This text concerns the computer-based design and modelling, computational approaches and instrumental methods for elucidating molecular mechanisms of protein folding. Ligand-acceptor interactions are included in volumes 202 and 203 as are genetic and chemical methods for the production of functional molecules including antibodies and antigens, enzymes, receptors, nucleic acids and polysaccharides and drugs.

Nuclear Magnetic Resonance, Part B, Volume 177 - Structure and Mechanism (Hardcover): John N. Abelson, Melvin I. Simon Nuclear Magnetic Resonance, Part B, Volume 177 - Structure and Mechanism (Hardcover)
John N. Abelson, Melvin I. Simon; Volume editing by Norman J. Oppenheimer, Thomas L. James
R1,564 Discovery Miles 15 640 Ships in 12 - 19 working days

This volume, as does Volume 176, provides a general background of modern NMR techniques, with a specific focus on NMR techniques that pertain to proteins and enzymology, and a "snapshot" of the current state-of-the-art in NMR experimental techniques. These books enable the reader to understand a given technique, to evaluate its strengths and limitations, to decide which is the best approach, and, finally, to design an experiment using the chosen technique to solve a problem.

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