This book constitutes the proceedings of the 15th Brazilian Symposium on Bioinformatics on Advances in Bioinformatics and Computational Biology, BSB 2022, which took place in Buzios, Brazil, in September 2022. The 10 full papers and 7 short papers presented in this volume were carefully reviewed and selected from 23 submissions. The papers focus on bioinformatics, computational biology, Biological Databases, Biological Networks, Cheminformatics, Evolutionary Genomics, Computational Proteomics, Systems Biology, Drug Design, Genomics, Machine Learning applications in Bioinformatics, Metagenomics, Molecular Docking and Modeling, Molecular Evolution and Phylogenetics, Protein Structure and Modeling, Proteomics, Transcriptomics, Single-Cell Analysis, Workflows in Bioinformatics.

Der vorliegende Band enthalt fur die Publikation uberarbeitete Beitrage des Symposiums Alexander von Humboldt Aufbruch in die Moderne, das begleitend zur Ausstellung Alexander von Humboldt-Netzwerke des Wissens (6. Juni 15. August 1999) im Berliner Haus der Kulturen der Welt stattfand, und einige weitere Beitrage zur Thematik von Autoren, die ebenfalls am Symposium beteiligt waren. Der Band ist jedoch kein Tagungsprotokoll, sondern will vielmehr als Lesebuch verstanden werden, das von der Symposiumsdiskussion ausgehend manchen Gedanken naher ausfuhrt und das eine oder andere Thema weiter expliziert. Dem entspricht die Gliederung in funf Themenkomplexe: Asthetische Reprasentationen in der Moderne; Spuren in der Moderne; Wissenschaft in der Moderne; Europa und Lateinamerika; Kommunikation in der Moderne. Bezeichnenderweise werden nicht nur unter dem Themenkomplex "Wissenschaft in der Moderne," sondern auch aus den gewahlten anderen Aufsichten auf die Gesamtproblematik Humboldts Wissenschaftsbegriff, sein Verhaltnis zu Erkenntis, Wissensentstehung und -verbreitung, zu Einzelwissenschaften, Theoriebildung und Integrationsprozessen, zu Bildungsvermittlung, Wissenstransfer und Kommunikation im weitesten Sinne reflektiert. Das fuhrt insbesondere zu der Frage an die heutigen Wissenschaften, wo und in welcher Form es ihnen gelingt, ganzheitliche Zusammenhange vor allem bezogen auf das Verhaltnis von Geistes- und Naturwissenschaften zu erfassen und darzustellen."

This is a succinct guide to the application and modelling of dependence models or copulas in the financial markets. First applied to credit risk modelling, copulas are now widely used across a range of derivatives transactions, asset pricing techniques and risk models and are a core part of the financial engineer's toolkit.

Why should manufacturing firms in many national industries maintain multiple small scale plants when they might produce the same output at a lower unit cost in a single large establishment? What specific benefits are attained through the operation of multiple plants? To address these questions, the authors conducted 125 in-depth interviews with businessmen actively involved in plant size and multi-plant operating decisions. They investigated the experience of twelve industries in six countries (West Germany, France, the United Kingdom, Sweden, Canada, and the United States). The authors develop an economic theory of plant size and multi-plant decisions and apply it to analyze the statistical and qualitative evidence on factors affecting plant size choices. They then examine the extent of multi-plant operation, its statistical correlate, and the economy actually or potentially realizable from various modes of multi-plant operation. Implications are drawn from antitrust and foreign trade policy, the evolution of scientific business management, and the development of industrial organization knowledge.

This is a reproduction of a book published before 1923. This book may have occasional imperfections such as missing or blurred pages, poor pictures, errant marks, etc. that were either part of the original artifact, or were introduced by the scanning process. We believe this work is culturally important, and despite the imperfections, have elected to bring it back into print as part of our continuing commitment to the preservation of printed works worldwide. We appreciate your understanding of the imperfections in the preservation process, and hope you enjoy this valuable book. ++++ The below data was compiled from various identification fields in the bibliographic record of this title. This data is provided as an additional tool in helping to ensure edition identification: ++++ Familienrecht Des Burgerlichen Gesetzbuches Fur Das Deutsche Reich: BGB. IV. Buch, section Symbol] section Symbol] 1297-1921 M. Scherer, Germany