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Transcription and Translation in Health and Disease provides a
detailed overview of the regulators underlying transcription and
translation in relation to a variety of human diseases and
disorders. Beginning with an introduction into the current
perspectives relating to these processes in human disease, the book
expands to focus on specific mechanisms underlying conditions such
as arthritis, cancer, neurological disorders, diabetes and
cardiovascular disease. This book considers RNA processing and
related mechanisms in eukaryotes including RNA splicing, RNA
binding proteins, RNA interference, microRNAs, RNA editing,
transcription factors, RNAi screening, CRISPR activation,
CRISPR-Cas9 interference, and post-translational modifications. It
provides a structured and detailed overview of the various
regulators underlying molecular processes and their impact on
health and disease, equipping readers with the necessary knowledge
for further investigation in the areas of treatment and therapeutic
intervention.
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