This comprehensive volume explores human genetic engineering its pre-clinical and clinical applications, current developments, and as treatment for hereditary diseases. It presents and evaluates the most recent advances in the understanding of mammalian host DNA repair mechanisms, such as double-strand break induced gene targeting and mutagenesis, the development of zinc-finger nucleases, genome editing for neuromuscular diseases, phase integrases, triplex forming oligonucleotides and peptide nucleic acids, aptamer-guided gene targeting, AAV gene editing via DSB repair, engineered nucleases and trinucleotide repeat diseases, and creation of HIV-resistant cells. The expertly authored chapters contextualize current developments within the history of genome editing while also discussing the current and potential safety concerns of this rapidly growing field. Genome Editing: The Next Step in Gene Therapy, the latest volume in the American Society of Gene and Cell Therapy series, deftly illuminates the potential of genetic engineering technology to eradicate today's deadliest and most prolific diseases. It is ideal reading for clinicians and researchers in genetics and immunology.

This comprehensive volume explores human genetic engineering its pre-clinical and clinical applications, current developments, and as treatment for hereditary diseases. It presents and evaluates the most recent advances in the understanding of mammalian host DNA repair mechanisms, such as double-strand break induced gene targeting and mutagenesis, the development of zinc-finger nucleases, genome editing for neuromuscular diseases, phase integrases, triplex forming oligonucleotides and peptide nucleic acids, aptamer-guided gene targeting, AAV gene editing via DSB repair, engineered nucleases and trinucleotide repeat diseases, and creation of HIV-resistant cells. The expertly authored chapters contextualize current developments within the history of genome editing while also discussing the current and potential safety concerns of this rapidly growing field. Genome Editing: The Next Step in Gene Therapy, the latest volume in the American Society of Gene and Cell Therapy series, deftly illuminates the potential of genetic engineering technology to eradicate today's deadliest and most prolific diseases. It is ideal reading for clinicians and researchers in genetics and immunology.

Publisher's Note: Products purchased from Third Party sellers are not guaranteed by the publisher for quality, authenticity, or access to any online entitlements included with the product. Practice the Computer Security Skills You Need to Succeed! 40+ lab exercises challenge you to solve problems based on realistic case studies Step-by-step scenarios require you to think critically Lab analysis tests measure your understanding of lab results Key term quizzes help build your vocabulary Labs can be performed on a Windows, Linux, or Mac platform with the use of virtual machines In this Lab Manual, you'll practice Configuring workstation network connectivity Analyzing network communication Establishing secure network application communication using TCP/IP protocols Penetration testing with Nmap, metasploit, password cracking, Cobalt Strike, and other tools Defending against network application attacks, including SQL injection, web browser exploits, and email attacks Combatting Trojans, man-in-the-middle attacks, and steganography Hardening a host computer, using antivirus applications, and configuring firewalls Securing network communications with encryption, secure shell (SSH), secure copy (SCP), certificates, SSL, and IPsec Preparing for and detecting attacks Backing up and restoring data Handling digital forensics and incident response Instructor resources available: This lab manual supplements the textbook Principles of Computer Security, Fourth Edition, which is available separately Virtual machine files Solutions to the labs are not included in the book and are only available to adopting instructors