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In the last 30 years, embodied, embedded, enactive, and extended
(4E) accounts of mind and experience have flourished. A more
cosmopolitan and pluralistic approach to the philosophy of mind has
also emerged, drawing on analytic, phenomenological, pragmatist,
and non-Western sources and traditions. This is the first book to
fully engages the 4E approach and Buddhist philosophy, drawing on
and integrating the intersection of enactivism and Buddhist
thought. This book deepens and extends the dialogue between
Buddhist philosophy and 4E philosophy of mind and phenomenology. It
engages with core issues in the philosophy of mind broadly
construed in and through the dialogue between Buddhism and
enactivism. Indian philosophers developed and defended
philosophically sophisticated and phenomenologically rich accounts
of mind, self, cognition, perception, embodiment, and more. As a
work of cross-cultural philosophy, the book investigates the nature
of mind and experience in dialogue with Indian and Western
thinkers. On the basis of this cross-traditional dialogue, the book
articulates and defends a dynamic, non-substantialist, and embodied
account of experience, subjectivity, and self.
This third edition is comprised of well-established protocols that
are considered the gold standard in the field as well as new
methodologies for mitochondrial DNA analysis. of Mitochondrial DNA:
Methods and Protocols describes protocols for detecting mutations
in mitochondrial DNA, techniques to assess mitochondrial DNA
damage, visualization of mitochondrial DNA in situ, detection of
mitochondrial DNA nucleoids within the mitochondria, methods for
analyzing mitochondrial DNA replication, mitochondrial DNA-encoded
protein translation and mitochondrial DNA copy number, the latest
technologies for modifying the mitochondrial genome and methods for
the purification of proteins involved in the replication and
transcription of mitochondrial DNA. Written for the Methods in
Molecular Biology series, chapters include introductions to their
respective topics, lists of the necessary materials and reagents,
step-by-step, readily reproducible laboratory protocols and tips on
troubleshooting and avoiding known pitfalls. Authoritative and
practical, Mitochondrial DNA: Methods and Protocols, Third Edition
will be useful not only for mitochondrial researchers but also for
scientists studying human diseases where mitochondrial DNA
variation has been recognized as an important pathogenic factor,
including cancer and neurodegeneration.
With skillful storytelling, Matthew McKenzie weaves together the
industrial, cultural, political, and ecological history of New
England's fisheries through the story of how the Boston haddock
fleet - one of the region's largest and most heavily industrialized
- rose, flourished, and then fished itself into near oblivion
before the arrival of foreign competition in 1961. This fleet also
embodied the industry's change during this period, as it shucked
its sail-and-oar, hook-and-line origins to embrace mechanized power
and propulsion, more sophisticated business practices, and
political engagement. Books, films, and the media have long
portrayed the Yankee fisherman's hard-scrabble existence, as he
faced brutal weather on the open seas and unnecessary governmental
restrictions. As McKenzie contends, this simplistic view has long
betrayed commercial fisheries' sophisticated legislative campaigns
in Washington, DC, as they sought federal subsidies and relief and,
eventually, fewer constricting regulations. This clash between
fisheries' representation and their reality still grips fishing
communities today as they struggle to navigate age-old trends of
fleet consolidation, stock decline, and intense competition.
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