This issue of Otolaryngologic Clinics, guest edited by Drs. Abtin Tabaee and Edward D. McCoul, is devoted to Refractory Chronic Rhinosinusitis. Articles in this issue include: Classification of Chronic Rhinosinusitis: Working Towards Personalized Diagnosis; Bacterial Pathogens and the Microbiome; Biofilm and Osteitis; Refractory Chronic Sinusitis with Polyposis; Aspirin-Exacerbated Respiratory Disease; Systemic and Odontogenic Etiologies in Chronic Rhinosinusitis; Genetic and Immune Dysregulation in Chronic Rhinosinusitis; Office Procedures in Refractory Chronic Rhinosinusitis; Topical Therapies and Stents; Revision Functional Endoscopic Sinus Surgery; Extended Endoscopic and Open Sinus Surgery for Refractory Chronic Rhinosinusitis; and An Algorithm for Comprehensive Evaluation and Management of Refractory Chronic Rhinosinusitis.

Providing a thorough review of the concept of the Institutional Repository (IR) the book examines how they can be set up, maintained and embedded into general institutional working practice. Specific reference is made to capturing certain types of research material such as E-Theses and E-Prints and what the issues are with regard to obtaining the material, ensuring that all legal grounds are covered and then storing the material in perpetuity. General workflow and administrative processes that may come up during the implementation and maintenance of an IR are discussed. The authors notes that there are a number of different models that have been adopted worldwide for IR management, and these are discussed. Finally, a case study of the inception of the Edinburgh Research Archive is provided which takes the user through the long path from conception to completion of an IR, examining the highs and lows of the process and offering advice for other implementers. This allows the book the opportunity to introduce extensive practical experience in unexpected areas such as mediated deposit.
A comprehensive synthesis of the whole of the IR system - never before provided in other booksThe research results that it contains, are at the leading edge of this subject areaIncludes a comprehensive case study and examination of practical experience - never before provided in other books

Unlike some other reproductions of classic texts (1) We have not used OCR(Optical Character Recognition), as this leads to bad quality books with introduced typos. (2) In books where there are images such as portraits, maps, sketches etc We have endeavoured to keep the quality of these images, so they represent accurately the original artefact. Although occasionally there may be certain imperfections with these old texts, we feel they deserve to be made available for future generations to enjoy.

Unlike some other reproductions of classic texts (1) We have not used OCR(Optical Character Recognition), as this leads to bad quality books with introduced typos. (2) In books where there are images such as portraits, maps, sketches etc We have endeavoured to keep the quality of these images, so they represent accurately the original artefact. Although occasionally there may be certain imperfections with these old texts, we feel they deserve to be made available for future generations to enjoy.

Unlike some other reproductions of classic texts (1) We have not used OCR(Optical Character Recognition), as this leads to bad quality books with introduced typos. (2) In books where there are images such as portraits, maps, sketches etc We have endeavoured to keep the quality of these images, so they represent accurately the original artefact. Although occasionally there may be certain imperfections with these old texts, we feel they deserve to be made available for future generations to enjoy.

Unlike some other reproductions of classic texts (1) We have not used OCR(Optical Character Recognition), as this leads to bad quality books with introduced typos. (2) In books where there are images such as portraits, maps, sketches etc We have endeavoured to keep the quality of these images, so they represent accurately the original artefact. Although occasionally there may be certain imperfections with these old texts, we feel they deserve to be made available for future generations to enjoy.

Unlike some other reproductions of classic texts (1) We have not used OCR(Optical Character Recognition), as this leads to bad quality books with introduced typos. (2) In books where there are images such as portraits, maps, sketches etc We have endeavoured to keep the quality of these images, so they represent accurately the original artefact. Although occasionally there may be certain imperfections with these old texts, we feel they deserve to be made available for future generations to enjoy.

'Essential reading, not just for anyone struggling with mental illness, but for anyone who knows someone who needs support. That's all of us' Daisy Buchanan, author of How to Be a Grown-Up'An essential, wondrous WOW of a book' Sarah Knight, New York Times bestselling author of The Life-Changing Magic of Not Giving a F**k It doesn't matter that you've lived in the shadows, that you've slept through years of your life, that you've done things you're shamed to admit even to yourself. It doesn't matter that you're an anxious mess with a shouty monster brain that keeps you from conforming to society's definition of normal. How to Come Alive Again is a relatable, honest, joyous and above all practical guide for anyone who has a mental illness - or anyone who knows and loves someone who does. Beth McColl shares what's worked for her and what hasn't, and what she wishes she'd known from the start: from advice on how get through a bad day to the truth about medication and what to expect from a partner. Here are the basics for mending your life, accepting yourself, and learning to live again.