This issue of Otolaryngologic Clinics, guest edited by Drs. Abtin Tabaee and Edward D. McCoul, is devoted to Refractory Chronic Rhinosinusitis. Articles in this issue include: Classification of Chronic Rhinosinusitis: Working Towards Personalized Diagnosis; Bacterial Pathogens and the Microbiome; Biofilm and Osteitis; Refractory Chronic Sinusitis with Polyposis; Aspirin-Exacerbated Respiratory Disease; Systemic and Odontogenic Etiologies in Chronic Rhinosinusitis; Genetic and Immune Dysregulation in Chronic Rhinosinusitis; Office Procedures in Refractory Chronic Rhinosinusitis; Topical Therapies and Stents; Revision Functional Endoscopic Sinus Surgery; Extended Endoscopic and Open Sinus Surgery for Refractory Chronic Rhinosinusitis; and An Algorithm for Comprehensive Evaluation and Management of Refractory Chronic Rhinosinusitis.

Providing a thorough review of the concept of the Institutional Repository (IR) the book examines how they can be set up, maintained and embedded into general institutional working practice. Specific reference is made to capturing certain types of research material such as E-Theses and E-Prints and what the issues are with regard to obtaining the material, ensuring that all legal grounds are covered and then storing the material in perpetuity. General workflow and administrative processes that may come up during the implementation and maintenance of an IR are discussed. The authors notes that there are a number of different models that have been adopted worldwide for IR management, and these are discussed. Finally, a case study of the inception of the Edinburgh Research Archive is provided which takes the user through the long path from conception to completion of an IR, examining the highs and lows of the process and offering advice for other implementers. This allows the book the opportunity to introduce extensive practical experience in unexpected areas such as mediated deposit.
A comprehensive synthesis of the whole of the IR system - never before provided in other booksThe research results that it contains, are at the leading edge of this subject areaIncludes a comprehensive case study and examination of practical experience - never before provided in other books

Unlike some other reproductions of classic texts (1) We have not used OCR(Optical Character Recognition), as this leads to bad quality books with introduced typos. (2) In books where there are images such as portraits, maps, sketches etc We have endeavoured to keep the quality of these images, so they represent accurately the original artefact. Although occasionally there may be certain imperfections with these old texts, we feel they deserve to be made available for future generations to enjoy.

Unlike some other reproductions of classic texts (1) We have not used OCR(Optical Character Recognition), as this leads to bad quality books with introduced typos. (2) In books where there are images such as portraits, maps, sketches etc We have endeavoured to keep the quality of these images, so they represent accurately the original artefact. Although occasionally there may be certain imperfections with these old texts, we feel they deserve to be made available for future generations to enjoy.

Unlike some other reproductions of classic texts (1) We have not used OCR(Optical Character Recognition), as this leads to bad quality books with introduced typos. (2) In books where there are images such as portraits, maps, sketches etc We have endeavoured to keep the quality of these images, so they represent accurately the original artefact. Although occasionally there may be certain imperfections with these old texts, we feel they deserve to be made available for future generations to enjoy.

Unlike some other reproductions of classic texts (1) We have not used OCR(Optical Character Recognition), as this leads to bad quality books with introduced typos. (2) In books where there are images such as portraits, maps, sketches etc We have endeavoured to keep the quality of these images, so they represent accurately the original artefact. Although occasionally there may be certain imperfections with these old texts, we feel they deserve to be made available for future generations to enjoy.

Unlike some other reproductions of classic texts (1) We have not used OCR(Optical Character Recognition), as this leads to bad quality books with introduced typos. (2) In books where there are images such as portraits, maps, sketches etc We have endeavoured to keep the quality of these images, so they represent accurately the original artefact. Although occasionally there may be certain imperfections with these old texts, we feel they deserve to be made available for future generations to enjoy.