This issue of Otolaryngologic Clinics, guest edited by Drs. Abtin
Tabaee and Edward D. McCoul, is devoted to Refractory Chronic
Rhinosinusitis. Articles in this issue include: Classification of
Chronic Rhinosinusitis: Working Towards Personalized Diagnosis;
Bacterial Pathogens and the Microbiome; Biofilm and Osteitis;
Refractory Chronic Sinusitis with Polyposis; Aspirin-Exacerbated
Respiratory Disease; Systemic and Odontogenic Etiologies in Chronic
Rhinosinusitis; Genetic and Immune Dysregulation in Chronic
Rhinosinusitis; Office Procedures in Refractory Chronic
Rhinosinusitis; Topical Therapies and Stents; Revision Functional
Endoscopic Sinus Surgery; Extended Endoscopic and Open Sinus
Surgery for Refractory Chronic Rhinosinusitis; and An Algorithm for
Comprehensive Evaluation and Management of Refractory Chronic
Rhinosinusitis.
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