This proceedings volume collects review articles that summarize research conducted at the Munich Centre of Advanced Computing (MAC) from 2008 to 2012. The articles address the increasing gap between what should be possible in Computational Science and Engineering due to recent advances in algorithms, hardware, and networks, and what can actually be achieved in practice; they also examine novel computing architectures, where computation itself is a multifaceted process, with hardware awareness or ubiquitous parallelism due to many-core systems being just two of the challenges faced. Topics cover both the methodological aspects of advanced computing (algorithms, parallel computing, data exploration, software engineering) and cutting-edge applications from the fields of chemistry, the geosciences, civil and mechanical engineering, etc., reflecting the highly interdisciplinary nature of the Munich Centre of Advanced Computing.

This handbook of kinin biology and biochemistry covers the current knowledgeof kinins, a family of peptides involved in numerous physiological and pathophysiological processes. Recent publications have shown that the kinin system is highly relevant in a variety of disease states such as diabetes, multiple sclerosis and traumatic injuries. Furthermore, the first drug targeting system has just been approved for clinical use. The goal of this book is to provide advanced students and researchers a basic understanding of the kinin system and its role within the various organ systems. The authors of this book are experts in their fields, including a Nobel Laureate.

This open access book documents and analyses the various interventions - legal, political, and even artistic - that followed the Ali Enterprises factory fire in Karachi, Pakistan, in 2012. It illuminates the different substantive and procedural aspects of the legal proceedings and negotiations between the various local and transnational actors implicated in the Ali Enterprises fire, as well as the legal and policy reforms sparked by the incident. This endeavour serves to embed these legal cases and reform efforts in the larger context of human and labour rights protection and global value chain governance. It also offers a concrete case study relevant for ongoing debates around the role of transnational approaches in making human rights litigation, advocacy, and law reform more effective. In this regard, the book interrogates and critically reflects on such legal campaigns and local and transnational reform work with a view to future transformative legal and social activism.

At first glance the sexual male seems easy to understand, but beneath the surface lie complexities that disrupt lives and relationships. Why can men be so distant in bed? Why do many men love porn so much? And can he love porn and still love his wife? Respected psychologist Michael Bader takes an honest look at the nuances of male sexuality, addressing issues such as sexual boredom, internet sex, and sexual fantasies that can leave women bewildered and men ashamed. Illustrated with engaging examples from his practice, Male Sexuality gives readers, both women and men, deeper understanding of male behavior from the flamboyant to the mundane. Through increased awareness of the psychology behind the sex, Bader aims to enhance individual self-esteem and improve communication in relationships.

The present book provides an introduction to using space-filling curves (SFC) as tools in scientific computing. Special focus is laid on the representation of SFC and on resulting algorithms. For example, grammar-based techniques are introduced for traversals of Cartesian and octree-type meshes, and arithmetisation of SFC is explained to compute SFC mappings and indexings. The locality properties of SFC are discussed in detail, together with their importance for algorithms. Templates for parallelisation and cache-efficient algorithms are presented to reflect the most important applications of SFC in scientific computing. Special attention is also given to the interplay of adaptive mesh refinement and SFC, including the structured refinement of triangular and tetrahedral grids. For each topic, a short overview is given on the most important publications and recent research activities.

This proceedings volume collects review articles that summarize research conducted at the Munich Centre of Advanced Computing (MAC) from 2008 to 2012. The articles address the increasing gap between what should be possible in Computational Science and Engineering due to recent advances in algorithms, hardware, and networks, and what can actually be achieved in practice; they also examine novel computing architectures, where computation itself is a multifaceted process, with hardware awareness or ubiquitous parallelism due to many-core systems being just two of the challenges faced. Topics cover both the methodological aspects of advanced computing (algorithms, parallel computing, data exploration, software engineering) and cutting-edge applications from the fields of chemistry, the geosciences, civil and mechanical engineering, etc., reflecting the highly interdisciplinary nature of the Munich Centre of Advanced Computing.

At first glance the sexual male seems easy to understand, but beneath the surface lie complexities that disrupt lives and relationships. Why can men be so distant in bed? Why do many men love porn so much? And can he love porn and still love his wife? Respected psychologist Michael Bader takes an honest look at the nuances of male sexuality, addressing issues such as sexual boredom, internet sex, and sexual fantasies that can leave women bewildered and men ashamed. Illustrated with engaging examples from his practice, Male Sexuality gives readers, both women and men, deeper understanding of male behavior from the flamboyant to the mundane. Through increased awareness of the psychology behind the sex, Bader aims to enhance individual self-esteem and improve communication in relationships.

This open access book documents and analyses the various interventions - legal, political, and even artistic - that followed the Ali Enterprises factory fire in Karachi, Pakistan, in 2012. It illuminates the different substantive and procedural aspects of the legal proceedings and negotiations between the various local and transnational actors implicated in the Ali Enterprises fire, as well as the legal and policy reforms sparked by the incident. This endeavour serves to embed these legal cases and reform efforts in the larger context of human and labour rights protection and global value chain governance. It also offers a concrete case study relevant for ongoing debates around the role of transnational approaches in making human rights litigation, advocacy, and law reform more effective. In this regard, the book interrogates and critically reflects on such legal campaigns and local and transnational reform work with a view to future transformative legal and social activism.

The present book provides an introduction to using space-filling curves (SFC) as tools in scientific computing. Special focus is laid on the representation of SFC and on resulting algorithms. For example, grammar-based techniques are introduced for traversals of Cartesian and octree-type meshes, and arithmetisation of SFC is explained to compute SFC mappings and indexings.

The locality properties of SFC are discussed in detail, together with their importance for algorithms. Templates for parallelisation and cache-efficient algorithms are presented to reflect the most important applications of SFC in scientific computing. Special attention is also given to the interplay of adaptive mesh refinement and SFC, including the structured refinement of triangular and tetrahedral grids. For each topic, a short overview is given on the most important publications and recent research activities."

Dieses Buch ist aus - vielleicht zu - grosser Distanz geschrieben. Zur be kannten Heimatlosigkeit zwischen den realisierten Gesellschaftsmodellen entwickelter kapitalistischer und staatssozialistischer Industriegesellschaf ten und der skeptischen Einsicht in die erstaunliche Ohnmacht alternati ver demokratisch-sozialistischer Projekte schart sich eine tiefsitzende 'Entfremdung' in der akademischen Welt. Diese Position des Fremden ist das Ergebnis mehrfacher Erfahrungen: der Erfahrung der Begrenztheit und auffalligen Selbstgenugsamkeit nationaler Wissenschaftstraditionen; der Abschottung der furs Studium sozialer Ungleichheit und kollektiven Handeins wichtigen Disziplinen; der kontraproduktiven und ritualisier ten Rivalitaten theoretischer Schulen und Traditionen, der uferlosen 'in teressierten' Missverstandnisse und der grundlegenden Ambiguitat der Basisbegriffe und Problemstrukturierungen; der Kluft zwischen steriler 'theoretischer Soziologie' und 'theorieloser Sozialgeschichte' in der Erfor schung sozialer Ungleichheit und kollektiven Handeins. Wir hoffen, dass diese Distanzierungen es erlauben, die gegenseitigen mindheiten der rivalisierenden Lager zu durchbrechen; dass die Position des Fremden neue und andere Perspektiven erlaubt. Aber wir wissen auch, dass diese Position wenig Ansatze bietet fur leichte Identifikationen. Wer sich zwischen die Fronten begibt, kann Feuer von beiden Seiten er warten. Dennoch ist unser Projekt von einer - vielleicht naiven - Hoff nung getragen: viele der das Forschungsfeld in hohem Masse charakterisierenden Un vereinbarkeiten sind das Ergebnis mangelnder Selbstreflexion der nor mativen und politischen Bindungen, sowohl der wissenschaftssystem externen wie der internen. Unbewusste Politisierung verhindert rclatio nale kognitive Autonomie (vgl. Bader 1988b) . Die Explikation der eigenen Wert- und Interessenbezuge verhindert Verstandigung keineswegs. Sie ist vielmehr Voraussetzung der Mog lichkeit relationaler kognitiver Autonomie ."