Survival analysis is a highly active area of research with applications spanning the physical, engineering, biological, and social sciences. In addition to statisticians and biostatisticians, researchers in this area include epidemiologists, reliability engineers, demographers and economists. The economists survival analysis by the name of duration analysis and the analysis of transition data. We attempted to bring together leading researchers, with a common interest in developing methodology in survival analysis, at the NATO Advanced Research Workshop. The research works collected in this volume are based on the presentations at the Workshop. Analysis of survival experiments is complicated by issues of censoring, where only partial observation of an individual's life length is available and left truncation, where individuals enter the study group if their life lengths exceed a given threshold time. Application of the theory of counting processes to survival analysis, as developed by the Scandinavian School, has allowed for substantial advances in the procedures for analyzing such experiments. The increased use of computer intensive solutions to inference problems in survival analysis~ in both the classical and Bayesian settings, is also evident throughout the volume. Several areas of research have received special attention in the volume.

Handbook of Survival Analysis presents modern techniques and research problems in lifetime data analysis. This area of statistics deals with time-to-event data that is complicated by censoring and the dynamic nature of events occurring in time. With chapters written by leading researchers in the field, the handbook focuses on advances in survival analysis techniques, covering classical and Bayesian approaches. It gives a complete overview of the current status of survival analysis and should inspire further research in the field. Accessible to a wide range of readers, the book provides: An introduction to various areas in survival analysis for graduate students and novices A reference to modern investigations into survival analysis for more established researchers A text or supplement for a second or advanced course in survival analysis A useful guide to statistical methods for analyzing survival data experiments for practicing statisticians

This literally "refreshing" collection is based on the notion that the future of bioethics is inseparable from its past. Seminal works provide a unique and relatively unexplored vehicle for investigating not only where bioethics began, but where it may be going as well. In this volume, a number of the pioneers in bioethics - Tom Beauchamp, Lisa Sowle Cahill, James Childress, Charles E. Curran, Patricia King, H. Tristram Engelhardt, William F. May, Edmund D. Pellegrino, Warren Reich, Robert Veatch and LeRoy Walters - reflect on their early work and how they fit into the past and future of bioethics. Coming from many disciplines, generations, and perspectives, these trailblazing authors provide a broad overview of the history and current state of the field. Invaluable to anyone with a serious interest in the development and future of bioethics, at a time when new paths into medical questions are made almost daily, "The Story of Bioethics" is a Baedeker beyond compare.

The definitive text on the full spectrum of neurology-updated and better than ever! Long considered the field's gold-standard text, Adams and Victor's Principles of Neurology provides the very latest treatment and management strategies needed to confidently handle both common and rare neurologic conditions. Presented in full color, this classic resource meets the needs of the aspiring clinician or the seasoned professional, and has been hailed as the most detailed, thorough, and authoritative text on the subject. Some of the features that have made this resource so renowned: The most cohesive and consistent approach to clinical management-acclaimed as the most readable book in the literature A scholarly approach that gives readers a comprehensive overview of every neurologic illness Unmatched coverage of signs and symptoms A focus on the full range of therapeutic options available to treat neurologic diseases, including drug therapy and rehabilitation methods Coverage of the most exciting discoveries and hypotheses of modern neuroscience that bear on and explain neurologic disease Puts the latest scientific discovery into a larger clinical context An evenness of style and a uniform approach to subject matter across subspecialties that allows a quick and easy review of each topic and condition More than 900 full-color, high-quality images and illustrations

Praise for A Passion for Giving "Klein and Berrie have produced a great book that manages to make complex issues simple. It blends with grace and craft the deep with the practical and the concrete with the philosophical. It is a precious tool for both the neophyte and the experienced philanthropist. It is both a useful manual and a profound exploration of the core values of giving. In a word, this book is a true gift." Andres Spokoiny, President and CEO, Jewish Funders Network "Through the years, many people have asked us why we set up our family foundation and how we went about accomplishing this goal. The 'why' is easy to answer: we are fortunate enough to be able to give back and help others in need. The 'how' is perfectly explained in this compelling and very informative book by Peter Klein and Angelica Berrie." Marilyn and Barry Rubenstein, The Marilyn and Barry Rubenstein Family Foundation "This book should be required reading for new donors and experienced philanthropists. Klein and Berrie have crafted a winning combination of practical guidelines and heartfelt personal accounts to create a moving call to action for anyone who wishes to give back. The stories remind us that when philanthropy, an intensely personal journey, is coupled with deep learning, transformation occurs for both the recipient and the donor." Debra Mesch, PhD, Professor and Director, Women's Philanthropy Institute, IUPUI "I wish I could have had this book to guide me and refer to as my wife, Andrea, and I launched our Harbor Glow Foundation a decade ago. We would have been much more efficient in the process and more focused in our direction from the get-go. Peter and Angelica capture the spirit and nitty-gritty of a family foundation." Michael Leeds, Co-Chair, Harbor Glow Foundation

This book provides an in-depth analysis of representations of female murderers in modern American drama. Paying close attention to the plays' plot, form, and style, the study seeks to come to terms with the dramatic and cultural function of this phenomenon. Given the rarity of female murder in real life, the popularity and prevalence of this theme in culture is striking and unsettling at the same time. After all, a woman who kills not only violates against basic social rules, but also upsets gender norms. This potential to break with an ideology that rests on hierarchically structured gender binaries equips the figure of the female murderer with the power to symbolically 'kill' established views about gender and sexuality. It is this ideologically disruptive potential that makes the female murderer a fascinating object of study, as her cultural figuration may provide information about the meaning assigned to women at a certain historical moment.

Tame your toddler with seven key shifts in mindset that will help you parent with clarity, calmness, and self-control Through stories from her practice, Claire Lerner shows parents how making critical mindshifts—seeing their children’s behaviors through a new lens —empowers parents to solve their most vexing childrearing challenges. This process puts parents back in the driver’s seat, where they belong and where their children need them to be. These real life stories provide a roadmap for how to tune into the root causes of children’s behavior and how to create and implement strategies that are tailored to the unique needs of each child and family. Through these stories, Claire provides a treasure trove of practical solutions that are based in science and which work in real life. Why Is My Child In Charge? picks up where other books have left parents hanging. Most parenting books offer solutions that sound good on paper but don’t work in practice. They are aspirational rather than achievable, or they offer one-size-fits-all approaches that don’t meet the needs of an individual child. They can compound parents’ feelings of frustration and thus, can be counterproductive. Case by case, Claire unpacks the individualized process she guides parents through to solve the most common challenges such as throwing tantrums in public; delaying bedtime for hours; refusing to participate in family mealtimes; and resisting potty training. Employing a relatable story-telling approach, Claire elucidates: The faulty mindsets that pose obstacles to parents seeing the situation more objectively The essential mindshifts that enable parents to quickly identify the root causes of the problem The Development of an action plan tailored to each unique child and family Why is My Child in Charge? Is like having a child development specialist in your home. It shows how you can develop “win-win” strategies that translate into adaptable, happy kids and calm, connected and in-control parents. It will help you be the parent you want to be.

Handbook of Survival Analysis presents modern techniques and research problems in lifetime data analysis. This area of statistics deals with time-to-event data that is complicated by censoring and the dynamic nature of events occurring in time. With chapters written by leading researchers in the field, the handbook focuses on advances in survival analysis techniques, covering classical and Bayesian approaches. It gives a complete overview of the current status of survival analysis and should inspire further research in the field. Accessible to a wide range of readers, the book provides: An introduction to various areas in survival analysis for graduate students and novices A reference to modern investigations into survival analysis for more established researchers A text or supplement for a second or advanced course in survival analysis A useful guide to statistical methods for analyzing survival data experiments for practicing statisticians

Survival analysis is a highly active area of research with applications spanning the physical, engineering, biological, and social sciences. In addition to statisticians and biostatisticians, researchers in this area include epidemiologists, reliability engineers, demographers and economists. The economists survival analysis by the name of duration analysis and the analysis of transition data. We attempted to bring together leading researchers, with a common interest in developing methodology in survival analysis, at the NATO Advanced Research Workshop. The research works collected in this volume are based on the presentations at the Workshop. Analysis of survival experiments is complicated by issues of censoring, where only partial observation of an individual's life length is available and left truncation, where individuals enter the study group if their life lengths exceed a given threshold time. Application of the theory of counting processes to survival analysis, as developed by the Scandinavian School, has allowed for substantial advances in the procedures for analyzing such experiments. The increased use of computer intensive solutions to inference problems in survival analysis~ in both the classical and Bayesian settings, is also evident throughout the volume. Several areas of research have received special attention in the volume.

Applied statisticians in many fields must frequently analyze time to event data. While the statistical tools presented in this book are applicable to data from medicine, biology, public health, epidemiology, engineering, economics, and demography, the focus here is on applications of the techniques to biology and medicine. The analysis of survival experiments is complicated by issues of censoring, where an individual's life length is known to occur only in a certain period of time, and by truncation, where individuals enter the study only if they survive a sufficient length of time or individuals are included in the study only if the event has occurred by a given date. The use of counting process methodology has allowed for substantial advances in the statistical theory to account for censoring and truncation in survival experiments. This book makes these complex methods more accessible to applied researchers without an advanced mathematical background. The authors present the essence of these techniques, as well as classical techniques not based on counting processes, and apply them to data. Practical suggestions for implementing the various methods are set off in a series of Practical Notes at the end of each section. Technical details of the derivation of the techniques are sketched in a series of Technical Notes. This book will be useful for investigators who need to analyze censored or truncated life time data, and as a textbook for a graduate course in survival analysis. The prerequisite is a standard course in statistical methodology.

25 Jahre sind vergangen seit der letzten zusammenfassenden Darstellung der Herzklappenerkrankungen in dem deutschen Schrifttum der pathologischen Ana- tomie. Eine gleichartige bakteriologische Bearbeitung hat es bislang in Deutsch- land nicht gegeben. Es erschien uns darum an der Zeit, eine Gemeinschaftsarbeit anzugehen, in der die pathologische Anatomie und die Bakteriologie der Endo- karditis gleichermaBen zu Wort und Darstellung kommt. Ware eine solche Synthese dieser beiden Forschungsgebiete fruher erfolgt, waren bei beiden Diszi- plinen manche schwerwiegend erscheinende Irrtumer unterblieben. Eine solche Gemeinschaftsarbeit ist unseres Erachtensdarum ein unbedingtes Erfordernis nicht nur fUr Beurteilung und Darstellung dieser Erkrankung, sondern fUr die aller pathologisch-anatomischen Veranderungen bei bakteriell-toxischen Er- krankungen. Diese Forderung und Grundlage war im vergangenen Jahrhundert und in dem ersten Dezennium dieses Jahrhunderts noch theoretisches und prak- tisches Allgemeingut der Pathologen in Deutschland. Wie vieles andere ist sie einem Spezialistentum zum Opfer gefallen. Wie wenig die Bakteriologie in kausaler und formaler Genese der Endokarditis bewertet wurde, geht aus der Darstellung aller Lehrbucher der speziellen pathologischen Anatomie und ebenso aus der Abhandlung im Handbuch der speziellen pathologischen Anatomie und Histologie hervor. In der praktischen und theoretischen Auswertung beider Fach- disziplinen sehen wir darum eine der Hauptaufgaben. Wir haben ernsthaft erwogen, ob nicht die Ausdehnung der Gemeinschaftsarbeit auf die Klinik moglich ware. Die Forderung hierzu steht auBer Zweifel. Jedoch waren zur Zeit unseres Arbeitsbeginnes die Vorbedingungen nicht gegeben. Zudem entgeht auch heute noch die Mehrzahl der verschiedenen Formen einer Herzklappenentzundung dem klinischen Nachweis, stellt die Mehrzahl einen Uberraschungsbefund bei der Sektion dar.

Der vor Gericht als Sachverstandiger wirkende Psychiater berat Richter und Staats an walt nicht in peripheren juristischen Fragen, sondern - wie es mein ver- ehrter Lehrer, Professor KURT SCHNEIDER, in seiner grundlegenden Schrift "Die Be- urteilung der Zurechnungsfahigkeit" formulierte - im "Zentrum des Rechtes". Dieses Zentrum des Strafrechtes ist die Frage der Schuld. An allen Bemiihungen urn die Neugestaltung des Strafrechtes nehmen wir somit lebhaften Anteil, da die Psychiatrie Wesentliches zu sagen hat, wenn es urn den Nachweis der Schuldunfahigkeit aus bio- logischen Griinden geht. Die vorliegende Studie solI einen Beitrag zur Strafrechtsreform bringen. Sie ba- siert auf dem forensischen Material der Keilner Universitats-Nervenklinik aus den Jahren 1950 bis 1958. Meinem verehrtem Chef, Herrn Professor WERNER SCHEID, mochte ich auch an dieser Stelle aufrichtig danken fiir die mir seit Beginn unserer gemeinsamen Arbeit groBziigig gegebene Moglichkeit, die forensischen Gutachten der Klinik fiir Forschung 1 und Lehre zu benutzen. In harmonischer Zusammenarbeit mit der Kolner Staatsanwaltschaft konnten wir die sich uns stellenden Forschungsaufgaben, aber auch die Frage der Gestaltung des akademischen Unterrichtes in auBerordentlich gliicklicher Weise los en. Den Mitarbei- tern der Kolner Behorde, vor allem den Herren Oberstaatsanwalten Dr. SCHWELLEN- BACH und Dr. KLEIN, schuld en wir Dank fiir die uns immer wieder gewahrte Unter- stiitzung.

This is a new release of the original 1944 edition.

The United States Geological Survey (USGS) is a scientific organization created in 1879, and is part of the U.S. government. Their scientists explore our environment and ecosystems, to determine the natural dangers we are facing. The agency has over 10,000 employees that collect, monitor, and analyze data so that they have a better understanding of our problems. The USGS is dedicated to provide reliable, investigated information to enhance and protect our quality of life. This is one of their reports.

Kessinger Publishing is the place to find hundreds of thousands of rare and hard-to-find books with something of interest for everyone!

Kessinger Publishing is the place to find hundreds of thousands of rare and hard-to-find books with something of interest for everyone!

Kessinger Publishing is the place to find hundreds of thousands of rare and hard-to-find books with something of interest for everyone!

In our increasingly technological society, improving students' performance in mathematics and science has become a critical challenge. During the 1990s, the National Science Foundation funded a series of Systemic Initiatives designed to change the way these subjects are being taught in schools throughout the country. These initiatives sought to align all aspects of the educational system in support of ambitious curriculum and performance standards, with particular emphasis on teacher training and professional development to promote effective changes in instructional practice.