This book constitutes the refereed proceedings of the 19th International Conference on Virtual Reality and Mixed Reality, EuroXR 2022, held in Stuttgart, Germany, in September 2022.The 6 full and 2 short papers were carefully reviewed and selected from 37 submissions. The conference presents contributions on results and insights in Virtual Reality (VR), Augmented Reality (AR), and Mixed Reality (MR), commonly referred to under the umbrella of Extended Reality (XR), including software systems, immersive rendering technologies, 3D user interfaces, and applications.