2015 BMA Medical Book Awards Highly Commended in Oncology Category! The Molecular Basis of Cancer arms you with the latest knowledge and cutting-edge advances in the battle against cancer. This thoroughly revised, comprehensive oncology reference explores the scientific basis for our current understanding of malignant transformation and the pathogenesis and treatment of this disease. A team of leading experts thoroughly explains the molecular biologic principles that underlie the diagnostic tests and therapeutic interventions now being used in clinical trials and practice. Detailed descriptions of topics from molecular abnormalities in common cancers to new approaches for cancer therapy equip you to understand and apply the complexities of ongoing research in everyday clinical application. Effectively determine the course of malignancy and design appropriate treatment protocols by understanding the scientific underpinnings of cancer. Visually grasp and retain difficult concepts easily thanks to a user-friendly format with abundant full-color figures. Find critical information quickly with chapters following a logical sequence that moves from pathogenesis to therapy. Stay current with the latest discoveries in molecular and genomic research. Sweeping revisions throughout include eight brand-new chapters on: Tumor Suppressor Genes; Inflammation and Cancer; Cancer Systems Biology: The Future; Biomarkers Assessing Risk of Cancer; Understanding and Using Information About Cancer Genomes; The Technology of Analyzing Nucleic Acids in Cancer; Molecular Abnormalities in Kidney Cancer; and Molecular Pathology. Access the entire text and illustrations online, fully searchable, at Expert Consult.

Now in four convenient volumes, Field’s Virology remains the most authoritative reference in this fast-changing field, providing definitive coverage of virology, including virus biology as well as replication and medical aspects of specific virus families. This volume of Field’s Virology: DNA Viruses, Seventh Edition covers the latest information on DNA viruses, how they cause disease, including cancer, how they persist in the body in a latent form, reactivate and spread, new therapeutics and vaccine approaches, as provided in new or extensively revised chapters that reflect these advances in this dynamic field.  Bundled with the eBook, which will be updated regularly as new information about each virus is available, this text serves as the authoritative, up-to-date reference book for virologists, infectious disease specialists, microbiologists, and physicians, as well as medical students pursuing a career in infectious diseases.  Covers both basic science and medical features of each virus, emphasizing viruses of medical importance and interest, while also including other viruses in specific cases where more is known about their mechanisms of replication or pathogenesis.   Covers viruses that cause human cancer such as human papillomaviruses (HPV), Epstein Barr Virus, the Merkel Cell Polyomavirus and hepatitis B virus, and viruses like the herpesviruses that persist in a latent form and can reactivate and cause acute and/or chronic disease.  Features more than 400 full-color illustrations, including key figures for use as lecture slides.  Provides quick, flexible access to current information both in print and in an improved eBook format.  Discusses virus structure, virus entry, replication, and assembly, virus-host cell interactions, host immune responses and vaccines, antiviral therapeutics, viral persistence and latency and viruses as tools for gene therapy and vectors for vaccination.   New and forthcoming Field’s Virology volumes, available in print and eBook format:  • Emerging Viruses  • DNA Viruses  • RNA Viruses  • Fundamental Viruses    Enrich Your eBook Reading Experience  Read directly on your preferred device(s), such as computer, tablet, or smartphone.  Easily convert to audiobook, powering your content with natural language text-to-speech. 

Now in four convenient volumes, Field’s Virology remains the most authoritative reference in this fast-changing field, providing definitive coverage of virology, including virus biology as well as replication and medical aspects of specific virus families. This volume of Field’s Virology: RNA Viruses, Seventh Edition covers the latest information on RNA viruses, how they cause disease, how they can cause epidemics and pandemics, new therapeutics and vaccine approaches, as provided in new or extensively revised chapters that reflect these advances in this dynamic field. Bundled with the eBook, which will be updated regularly as new information about each virus is available, this text serves as the authoritative, up-to-date reference book for virologists, infectious disease specialists, microbiologists, and physicians, as well as medical students pursuing a career in infectious diseases. Covers both basic science and medical features of each virus, emphasizing viruses of medical importance and interest, while also including other viruses in specific cases where more is known about their mechanisms of replication or pathogenesis Includes two new chapters on SARS - Coronavirus 2 covering both basic science and clinical aspects of CoV2 and COVID-19 Covers human immunodeficiency virus (HIV), rotaviruses, respiratory syncytial virus (RSV), measles virus, and more Features more than 400 full-color illustrations, including key figures for use as lecture slides Provides quick, flexible access to current information both in print and in an improved eBook format Discusses virus structure, virus entry, replication, and assembly, virus-host cell interactions, host immune responses and vaccines, antiviral therapeutics, viral persistence and latency for HIV, and mechanisms of viral oncogenesis for HTLV-1 and HCV New and forthcoming Field’s Virology volumes, available in print and eBook format: • Emerging Viruses - 2020 • DNA Viruses - 2021 • RNA Viruses • Fundamental Virology   Enrich Your eBook Reading Experience Read directly on your preferred device(s),such as computer, tablet, or smartphone. Easily convert to audiobook,powering your content with natural language text-to-speech.

In recent years there has been an explosion in research on the papillo- maviruses. The viral nature of human warts was first suggested 80 years ago by Ciuffo, who demonstrated transmission using cell-free filtrates. Shope described the first papillomavirus over 50 years ago as the etiologic agent in infectious papillomatosis in rabbits. Subsequent studies by Rous established that benign rabbit papillomas induced by this virus could progress to carcinomas when treated with specific nonviral cofactors. Despite these rich beginnings, the papillomavirus field lay virtually dor- mant until the late 1970s because no one was able to propagate these viruses in culture successfully. In the late 1970s the molecular cloning of the papillomavirus genomes permitted investigators to partially cir- cumvent this obstacle to their progress. The cloning of the viral genomes permitted the standardization of viral reagents and provided sufficient material to begin a systematic evaluation of the biology of this group of viruses.

Selected as a Doody's Core Title for 2022 and 2023! Now in four convenient volumes, Fields Virology remains the most authoritative reference in this fast-changing field, providing definitive coverage of virology, including virus biology as well as replication and medical aspects of specific virus families. This volume of Fields Virology: Emerging Viruses, Seventh Edition covers recent changes in emerging viruses, providing new or extensively revised chapters that reflect these advances in this dynamic field.   Bundled with the eBook, which will be updated regularly as new information about each virus is available, including coronavirus and COVID-19, this text serves as the authoritative, up-to-date reference book for virologists, infectious disease specialists, microbiologists, and physicians, as well as medical students pursuing a career in infectious diseases. Covers both basic science and medical features of each virus, emphasizing viruses of medical importance and interest, while also including other viruses in specific cases where more is known about their mechanisms of replication or pathogenesis. Covers virus evolution, as well as Coronoviridae, Picornaviridae, Enteroviruses, Caliciviridae, Hepatitis C Virus, Filoviridae, Henipaviruses, Orthomyxoviruses, Bunyavirales, Arenaviridae, and much more. Features over 500 full-color illustrations, including key figures for use as lecture slides. Provides quick, flexible access to current information both in print and in an improved eBook format, searchable across all volumes. Discusses virus structure, virus entry, replication, and assembly, virus-host cell interactions, host immune responses and vaccines, antiviral therapeutics, virus evolution and immunization.  New and forthcoming Fields Virology volumes, available in print and eBook format, which are sold separately: Emerging Viruses DNA Viruses RNA Viruses Fundamental Viruses Enrich Your eBook Reading Experience Read directly on your preferred device(s), such as computer, tablet, or smartphone. Easily convert to audiobook, powering your content with natural language text-to-speech.

Virus de ADN es el segundo volumen de la 7.a edicion de Fields. Virologia, la referencia de mayor autoridad en el tan cambiante mundo contemporaneo de la virologia. Esta edicion cubre la informacion mas reciente sobre los virus de ADN, la fisiopatologia de los padecimientos que causan, como persisten en el cuerpo en forma latente, se reactivan y se propagan, y los nuevos enfoques terapeuticos y de vacunas. Ademas, brinda una cobertura amplia que incluye la biologia de los virus, su replicacion y los aspectos clinicos de familias especificas de virus. Su contenido abarca todos los virus de ADN de importancia medica, incluidos los que infectan a los seres humanos y a los animales. Ademas, se plantean varias cuestiones tematicas al examinar los virus de ADN. La organizacion de los capitulos de esta edicion es similar a las anteriores, es decir, la mayoria de los virus se presenta en un unico capitulo que combina los aspectos basicos y clinicos de este. Para otros, la virologia basica relacionada con la replicacion y la patogenesis viricas se divide en dos capitulos. Esta 7. edicion de Fields. Virologia. Virus de ADN presentada a todo color, con multiples ilustraciones clinicas, figuras y tablas, esta dirigida a estudiantes y profesionales de la virologia, enfermedades infecciosas, microbiologia, medicina interna, familiar, epidemiologia, investigadores, inmunologos y otros profesionales en contacto con pacientes con enfermedades de origen viral.