The Epidemiological Approach to the Study of Protease Inhibitors (Fontham, Correa). In vitro Studies of Anticarcinogenic Protease Inhibitors (Kennedy). Discovery and Background of the BowmanBirk Protease Inhibitors (Bowman). Antigenicity of Soybean Protease Inhibitors (Bandon et al.). Low Molecular Weight Protease Inhibitors of Microbial Origin (Umezawa et al.). Protease Inhibitor Synthesis by MCF7 Breast Cancer Cells (Finlay et al.). Analysis of StructurActivity Relationships of the BowmanBirk Inhibitor of Serine Proteases (Flecker). Prevention of Cancer by Vitamin B3 (Troll). Approaches to Studying the Target Enzymes of Anticarcinogenic Protease Inhibitors (Billings). Anticarcinogenic Activities of Naturally Occuring Cysteine Protease Inhibitors (Colella et al.). Cell Membrane Enzymes Containing ChymotrypsinLike Activity (Yavelow et al.). The Role of Active Oxygen Species in Biological Damage and the Effect of Some Chemopreventative Agents (Frenkel). 6 additional articles. Index.

British children were mobilised for total war in 1914-18. War dominated their teaching and school experience, it was the focus of their extra curricular activities and they enjoyed it as a source of entertainment in literature and play. Children were not shielded from the war because it was believed their support was vital for Britain's present and future.
The study of children's lives provides a unique perspective on British society during the First World War. It lets us get to the very essence of how Britain's adults perceived the war and allows us to explore the methods society used to communicate with itself. Children's connection to the war, however, was personal. Millions had a relative in the army and those that did not had friends, neighbours and teachers involved in the fighting. Their participation, therefore, while shaped by adults, was motivated by a desire to remain in touch with their absent fathers and brothers.

The conquest of Wales by the medieval English throne produced a fiercely contested territory, both militarily and culturally. Wales was left fissured by frontiers of language, jurisdiction and loyalty--a reluctant meeting place of literary traditions and political cultures. But the profound consequences of this first colonial adventure on the development of medieval English culture have been disregarded. In setting English figurations of Wales against the contrasted representations of the Welsh language tradition, this volume seeks to reverse this neglect, insisting on the crucial importance of the English experience in Wales for any understanding of the literary cultures of medieval England and medieval Britain.

This collection is the work of scholars on Middle English, Insular French and Medieval Latin writings of the late twelfth century in England and its possessions, when an English-speaking populace was ruled by a French-speaking aristocracy and administered by a Latin-speaking and writing clergy. The political discourses of Henry's reign are acknowledged, developed and ironised within the first real flowering of so many vernacular genres, romance and history in particular. The energetic and intrepid writers of this period are examined in relation to the development of social institutions and emergent ideas of 'nationhood', as the literature of Henry's court is shown to act as an echo-chamber within which anxieties about the proper exercise of power in a legal order founded on martial conquest could be reflected and soothed.

How do we account for experiences of trauma and memory in multicultural and "globalized" societies? World Memory blends the study of trauma and memory with perspectives from postcolonial theory to explore a range of traumatic personal and socio-historical experiences: 9/11/01, the Holocaust, Stolen Generations, Apartheid, racism, sexual abuse, migration, and Diaspora. From diverse disciplinary bases, the writers examine psychoanalytic, artistic, literary, and vernacular accounts of trauma, collectively revealing what happens when languages of memory traverse boundaries of culture, space, and time.

Through a series of close readings of most of Rousseau's major writings, this book provides a new interpretation of the eighteenth-century philosopher's sexual politics. The text argues that Rousseau's writings provide a critique of not only normative gender identity, but also normative familial and kinship relations.

International and global in nature, Dubai - The Epicenter of Modern Innovation: A Guide to Implementing Innovation Strategies provides a roadmap for the successful implementation of innovation for companies and businesses currently working in the Middle East, the UAE, and more specifically, Dubai. The discussion focuses on implementing sustained innovation success within several industry segments, while identifying past, current, and future innovation-related successes that are leading to Dubai's rise as the epicenter of innovation in the Middle East and most notably, the world. The authors share key innovation leadership philosophies from Sheikh Mohammed bin Al Maktoum, recognized business leaders, and the highest levels in the UAE. This book: Features key leadership and innovation insights relative from the highest levels of government, including Sheikh Mohammed bin Al Maktoum and multiple UAE ministry officials. Focuses on the United Arab Emirates (UAE), most specifically, Dubai and the Nation's preparation for hosting World Expo 2020. Contains numerous examples of past, present, and future innovations in Dubai. Provides an easy to implement innovation process management methodology, which has been tested to work in various businesses and organizations. Authored by individuals who have 'on the ground' experience living and working with the chief architects of Dubai's innovation vision and strategy. This book will attempt to take the reader through the construct of this new innovative revolution, particularly in Dubai, and provide a bird's-eye view of how it came about. Most notably, the discussion will walk the reader through key milestones instrumental to Dubai's success-such as the present and past leadership, culture, strategy, and strategic vision. In addition, the discussion will present an industry agnostic, agile and progressive approach to building and leading successful innovation teams through to a successful project out-come and the attributes of good innovation leadership.

Innovation Project Management Handbook provides organizational leaders and decision-makers with a cadre of agile, disciplined, and transformational tools and processes for improving innovation opportunity outcomes and achieving sustained innovation project success. The authors introduce new tools and processes developed over their decades of work in the field of innovation that assist organizations in aligning innovation opportunity decisions with their core competencies, business objectives, and strategic vision. In concert with accepted tools already in use today, you are provided a detailed description of each tool and process in an "easy to follow" format with actual application scenarios and exercises. The handbook begins with an innovation primer and introductory discussion on how the authors evolved the original ENOVALE model into the N2OVATE methodology. An overview of how to select a project for each type of innovation opportunity is provided, followed by an in-depth, step-by-step discussion on how to implement each innovation process type. Based on innovative outcomes, the authors identify seven unique processes, each having its own unique circumstances. This allows you to tailor the processes and associated tool-sets to the needs of your organization and situation. After selecting one of the seven processes that fit your desired innovation outcome, you simply follow the detailed process maps provided in the applicable chapter to achieve a desired outcome. In doing so, you will learn how to use, adapt, and improve the tools and techniques offered in the handbook to achieve a positive innovation outcome and add value to your organization, customers, stakeholders, and shareholders.

International and global in nature, Dubai - The Epicenter of Modern Innovation: A Guide to Implementing Innovation Strategies provides a roadmap for the successful implementation of innovation for companies and businesses currently working in the Middle East, the UAE, and more specifically, Dubai. The discussion focuses on implementing sustained innovation success within several industry segments, while identifying past, current, and future innovation-related successes that are leading to Dubai's rise as the epicenter of innovation in the Middle East and most notably, the world. The authors share key innovation leadership philosophies from Sheikh Mohammed bin Al Maktoum, recognized business leaders, and the highest levels in the UAE. This book: Features key leadership and innovation insights relative from the highest levels of government, including Sheikh Mohammed bin Al Maktoum and multiple UAE ministry officials. Focuses on the United Arab Emirates (UAE), most specifically, Dubai and the Nation's preparation for hosting World Expo 2020. Contains numerous examples of past, present, and future innovations in Dubai. Provides an easy to implement innovation process management methodology, which has been tested to work in various businesses and organizations. Authored by individuals who have 'on the ground' experience living and working with the chief architects of Dubai's innovation vision and strategy. This book will attempt to take the reader through the construct of this new innovative revolution, particularly in Dubai, and provide a bird's-eye view of how it came about. Most notably, the discussion will walk the reader through key milestones instrumental to Dubai's success-such as the present and past leadership, culture, strategy, and strategic vision. In addition, the discussion will present an industry agnostic, agile and progressive approach to building and leading successful innovation teams through to a successful project out-come and the attributes of good innovation leadership.

This brief focuses on translational criminology practices as they relate to counter-terrorism and homeland security. The work provides a detailed and practical examination of how global threats (such as, terrorism and cybercrime) are managed through local response. It covers emerging strategies in data collection procedures, inter-agency cooperation, and new analytical techniques including risk-terrain modeling. In addition, it presents a common methodology, including steps in risk assessment, risk management, and decision-making, that can be used to frame and analyze global and local threats. The authors examine these issues using examples of how law enforcement responded to specific security threats including the 2013 Boston Marathon bombings, the 2003 terrorist attack in Istanbul, Turkey, and the 2010 Stuxnet attack on the Natanz nuclear facility in Iran.
This work expands on existing literature covering the impact that globalization has on cross national threats, drawing on disciplines related to criminology, such as international relations and political science. "

British children were mobilised for total war in 1914-18. It dominated their school experience and they enjoyed it as a source of entertainment. Their support was believed to be vital for Britain's present and future but their participation was motivated by a desire to remain connected to their absent fathers and brothers.

Through a series of close readings of most of Rousseau's major writings, this book provides a new interpretation of the eighteenth-century philosopher's sexual politics. The text argues that Rousseau's writings provide a critique of not only normative gender identity, but also normative familial and kinship relations.

Innovation Project Management Handbook provides organizational leaders and decision-makers with a cadre of agile, disciplined, and transformational tools and processes for improving innovation opportunity outcomes and achieving sustained innovation project success. The authors introduce new tools and processes developed over their decades of work in the field of innovation that assist organizations in aligning innovation opportunity decisions with their core competencies, business objectives, and strategic vision. In concert with accepted tools already in use today, you are provided a detailed description of each tool and process in an "easy to follow" format with actual application scenarios and exercises. The handbook begins with an innovation primer and introductory discussion on how the authors evolved the original ENOVALE (TM) model into the N2OVATE (TM) methodology. An overview of how to select a project for each type of innovation opportunity is provided, followed by an in-depth, step-by-step discussion on how to implement each innovation process type. Based on innovative outcomes, the authors identify seven unique processes, each having its own unique circumstances. This allows you to tailor the processes and associated tool-sets to the needs of your organization and situation. After selecting one of the seven processes that fit your desired innovation outcome, you simply follow the detailed process maps provided in the applicable chapter to achieve a desired outcome. In doing so, you will learn how to use, adapt, and improve the tools and techniques offered in the handbook to achieve a positive innovation outcome and add value to your organization, customers, stakeholders, and shareholders.

The conquest of Wales by the medieval English throne produced a fiercely contested territory, both militarily and culturally. Wales was left fissured by frontiers of language, jurisdiction and loyalty - a reluctant meeting place of literary traditions and political cultures. But the profound consequences of this first colonial adventure on the development of medieval English culture have been disregarded. In setting English figurations of Wales against the contrasted representations of the Welsh language tradition, this volume seeks to reverse this neglect, insisting on the crucial importance of the English experience in Wales for any understanding of the literary cultures of medieval England and medieval Britain.

This book depicts the trials and tribulations when trying to restore speech to Erik who was locked-in (paralyzed and mute) at age 16. We implanted electrodes into his brain, initiating a decade of breakthrough research in speech recovery. It lead to the author's own brain implant and the consequent successful offline development of the speech prosthetic whereby mute, locked-in people can speak. Part 1 is Erik's story of how he became locked-in following a brainstem stroke, and our efforts to break him out of his locked-in state by helping him speak. It describes my decision making, the tremendous contribution of his family, their anguish and the very relevant comparison with famous locked-in people, namely, Stephen Hawking and Jean-Dominique Bauby (The Diving Bell and the Butterfly). Part 2 documents conversations between myself and Erik's Dad, Eddie. Eddie describes how he was trained in a rehabilitation hospital to take care of his son. His 16-year devotion to his son is unparalleled and heroic. This part also contains important contributions from other researchers in the field, in a question and answer format. Part 3 is a condensed version of the scientific aspects of this research written for the non-scientist. Figures and videos on the website augment the text. Importantly, there is a full documentary associated with this book.

"A Companion to Woodrow Wilson" presents a compilation of essays contributed by various scholars in the field that cover all aspects of the life and career of America's 28th president.Represents the only current anthology of essays to introduce readers to the scholarship on all aspects of Wilson's life and careerOffers a 'one stop' destination for anyone interested in understanding how the scholarship on Wilson has evolved and where it stands now