This book is based on the NATO Advanced Research Workshop on "Mesenchymal-Epithelial Interactions in Neural Development" which was held in Berlin during March 1986. The idea that it may be the time for this workshop arose from a discussion among the organizers who met at a conference in Innsbruck. During the twenties, Spemann demonstrated that, in vertebrates, the formation of neuroepithelium depends on the induction by specific mesodermal derivatives. This was about the first time that mesenchymal-epithelial interactions had been recognized as an important mechanism in the development of an epithelial organ. Since then two things had become clear: 1) The identity and role of molecules, elaborated at mesenchymal-neuroepithelial interfaces had been partially elucidated in spinal cord and peripheral nerve ontogeny but, until recently, had been ignored in studies on the development of the brain. 2) In many-non-neural epithelia, the surrounding mesenchyme regulates such fundamental developmental steps as, for example, cell proliferation, morphogenesis and cell differentia tion, and there is no reason to exclude similar influences and interactions from brain development. It seemed to us that the importance and implications of many of these findings had not been appreciated by many developmental neurobiologists and that an attempt should be made to initiate discussions and exchange of ideas among different groups of scientists involved in extracellular matrix (ECM) research. This turned out to be a formidable task because of the great diversity of disciplines contributing findings to this active field."

1.1 Life Cycle Assessment (LeA): a fascinating and sophisticated tool The greening of the economy is not a new task, but it is a challenge for which a lot of tasks still have to be done. It is known that the main source of environ mental deterioration by industry is not any more the chimneys and other process related emissions, but the products and services produced. Products are regarded as carriers of polIution: they are not only a potential source of polIution and waste during their use; they are also a cause of resource depletion, energy consumption, and emissions du ring their life starting with the extraction of the raw materials and ending with their disposal (i.e. connecting production and consumption stages). The challenge of these decades is now the greening of products and services. The new focus on products (cp. OosterhuislRubik/ScholI 1996) was introduced as a policy approach of shared responsibility in which different actors are in volved along the life-cycle of a product, each having specific responsibilities."

The challenge of our time is the greening of products. Different tools and concepts to support this process have been developed in the past decade. Among others, Life Cycle Assessment (LCA) appears as one of the most instructive management instruments for gaining insight into product-related environmental impacts and for supporting an effective integration of environmental aspects in business and economy. Research on LCA was and still is focused on improving the methodology. In fact, the "LCA technique" has significantly improved over the last few years. However, this research progress did nearly not stress the application context of LCA and its embodiment into business and industry. This is precisely the primary focus of the present book. Based on the empirical information of a large survey and of 20 company case studies, the book describes the set of applications and uses, as well as the dynamics of the adoption and integration patterns of LCA within business and industry.

At the end of the nineteenth century, controversy arose as to precisely when the first glial cells originate during development of the central nervous system, and to date, the issue has not been satisfactorily resolved. His (1889, 1890) noted that, even in the earliest developmental stages of the germinallayer, there appeared to be two distinct cell types. The cells which he called Spongioblasten were thought to be glial precursors from which all mature glial cells derive; Keimzellen, in contrast, were regarded as forming 1 neurons. His was working on the assumption that the very first preneurons migrate into a preexisting framework of glial eelIs. In contrast to this view, Schaper (1897) regarded both Keimzellen and Spongioblasten as belonging to a common population of proliferating and pluripotent stem cells which begin differentiation into glial and neuronal cells at late developmental stages. It is this latter view which is the basis of the most recent studies on the subject (e. g. , Caley and Maxwell1968a, 1968b; DeVitry et al. 1980). The concept of one common stem cell seemed to be supported both by experiments using 3H-thymidine autoradiography (Fujita 1963, 1965b, 1966; Sauer and Walker 1959; Sidman et al. 1959) and by ultrastructural studies (Fu- jita 1966; Hinds and Ruffet 1971; Wechseler and Meller 1967) indicating that structural differences, which His presumably used to define his two cell types, could be related to different stages of the mitotic cycle.

The author is an important but controversial figure in the history of Palestinian archaeology. This volume celebrates the centennial of the publication of his excavations at Tel Gezer (1912), conducted under the auspices of the PEF. This excavation was the most ambitious one of its time in the land, yielding important architectural remains and thousands of artefacts, including the well-known Gezer Calendar. The contributions of several eminent scholars reflect on the man and his work, and also report on how his work influenced the understanding of the sites he excavated in Palestine, all of which are currently being re-investigated. It is also richly illustrated with images from the PEF archives. Evaluations of Macalister's work vary tremendously and are reflected here. Many learnt from him, others deplored his methods and record keeping. As one contributor puts it, 'an industrious archaeologist but an awful excavator', and a man who was both admired and intensely disliked: regarded as both a villain and a visionary. But it is generally agreed that he is a figure who cannot be ignored, and anyone interested in Palestinian archaeology will find a great deal to learn from this book.

Coaching kids is a whole different ball game, and this comprehensive guide supplies all the right moves. It's loaded with information, tools, and techniques to help children excel in sports, from helping them choose the right sport to making sure they're having fun.

Foolproof techniques for teaching good sportsmanship include:

• How to motivate: from pep-talks to post-game analysis.
• Easy ways to recognize and prevent sports burnout."
• Tips for managing difficult kids, umpires, and parents.

Your guide is a Sports Illustrated columnist and nationally recognized expert who knows how to show parents and coaches how to unleash kids' athletic potential. "

This is an EXACT reproduction of a book published before 1923. This IS NOT an OCR'd book with strange characters, introduced typographical errors, and jumbled words. This book may have occasional imperfections such as missing or blurred pages, poor pictures, errant marks, etc. that were either part of the original artifact, or were introduced by the scanning process. We believe this work is culturally important, and despite the imperfections, have elected to bring it back into print as part of our continuing commitment to the preservation of printed works worldwide. We appreciate your understanding of the imperfections in the preservation process, and hope you enjoy this valuable book.

The author is an important but controversial figure in the history of Palestinian archaeology. This volume celebrates the centennial of the publication of his excavations at Tel Gezer (1912), conducted under the auspices of the PEF. This excavation was the most ambitious one of its time in the land, yielding important architectural remains and thousands of artefacts, including the well-known Gezer Calendar. The contributions of several eminent scholars reflect on the man and his work, and also report on how his work influenced the understanding of the sites he excavated in Palestine, all of which are currently being re-investigated. It is also richly illustrated with images from the PEF archives. Evaluations of Macalister's work vary tremendously and are reflected here. Many learnt from him, others deplored his methods and record keeping. As one contributor puts it, 'an industrious archaeologist but an awful excavator', and a man who was both admired and intensely disliked: regarded as both a villain and a visionary. But it is generally agreed that he is a figure who cannot be ignored, and anyone interested in Palestinian archaeology will find a great deal to learn from this book.

This important new work from Rebell and Wolff, authors of the groundbreaking volume "Moving Every Child Ahead: From NCLB Hype to Meaningful Educational Opportunity", brings together the nation's leading researchers and thinkers in the field of educational equity to provide a range of provocative critiques that go well beyond what has already been said on the subject of No Child Left Behind (NCLB). Unlike most books, this one puts aside political rhetoric and quick-fix solutions to tackle the truly difficult questions about how to ensure meaningful educational opportunities for all children.