The amount of information that can be obtained by using molecular techniques in evolution, systematics and ecology has increased exponentially over the last ten years. The need for more rapid and efficient methods of data acquisition and analysis is growing accordingly. This manual presents some of the most important techniques for data acquisition developed over the last years. The choice and justification of data analysis techniques is also an important and critical aspect of modern phylogenetic and evolutionary analysis and so a considerable part of this volume addresses this important subject. The book is mainly written for students and researchers from evolutionary biology in search for methods to acquire data, but also from molecular biology who might be looking for information on how data are analyzed in an evolutionary context. To aid the user, information on web-located sites is included wherever possible. Approaches that will push the amount of information which systematics will gather in the

Phylogenomics: A Primer, Second Edition is for advanced undergraduate and graduate biology students studying molecular biology, comparative biology, evolution, genomics, and biodiversity. This book explains the essential concepts underlying the storage and manipulation of genomics level data, construction of phylogenetic trees, population genetics, natural selection, the tree of life, DNA barcoding, and metagenomics. The inclusion of problem-solving exercises in each chapter provides students with a solid grasp of the important molecular and evolutionary questions facing modern biologists as well as the tools needed to answer them.

Invertebrate Zoology: A Tree of Life Approach is a comprehensive and authoritative textbook adopting an explicitly phylogenetic organization. Most of the classical anatomical and morphological work has not been changed - it established the foundation of Invertebrate Zoology. With the explosion of Next-Generation Sequencing approaches, there has been a sea-change in the recognized phylogenetic relationships among and between invertebrate lineages. In addition, the merger of evolutionary and developmental biology (evo-devo) has dramatically contributed to changes in the understanding of invertebrate biology. Synthesizing these three approaches (classical morphology, sequencing data, and evo-devo studies) offers students an entirely unique perspective of invertebrate diversity. Key Features One of the first textbooks to combine classical morphological approaches and newer evo-devo and Next-Generation Sequencing approaches to address Invertebrate Zoology Organized along taxonomic lines in accord with the latest understanding of invertebrate phylogeny Will provide background in basic systematic analysis useful within any study of biodiversity A wealth of ancillary materials for students and teachers, including downloadable figures, lecture slides, web links, and phylogenetic data matrices

Phylogenomics: A Primer, Second Edition is for advanced undergraduate and graduate biology students studying molecular biology, comparative biology, evolution, genomics, and biodiversity. This book explains the essential concepts underlying the storage and manipulation of genomics level data, construction of phylogenetic trees, population genetics, natural selection, the tree of life, DNA barcoding, and metagenomics. The inclusion of problem-solving exercises in each chapter provides students with a solid grasp of the important molecular and evolutionary questions facing modern biologists as well as the tools needed to answer them.

The human species is very young, but in a short time it has acquired some striking, if biologically superficial, variations across the planet. As this book shows, however, none of those biological variations can be understood in terms of discrete races, which do not actually exist as definable entities. Starting with a consideration of evolution and the mechanisms of diversification in nature, this book moves to an examination of attitudes to human variation throughout history, showing that it was only with the advent of slavery that considerations of human variation became politicized. It then embarks on a consideration of how racial classifications have been applied to genomic studies, demonstrating how individualized genomics is a much more effective approach to clinical treatments. It also shows how racial stratification does nothing to help us understand the phenomenon of human variation, at either the genomic or physical levels.

The amount of information that can be obtained by using molecular techniques in evolution, systematics and ecology has increased exponentially over the last ten years. The need for more rapid and efficient methods of data acquisition and analysis is growing accordingly. This manual presents some of the most important techniques for data acquisition developed over the last years. The choice and justification of data analysis techniques is also an important and critical aspect of modern phylogenetic and evolutionary analysis and so a considerable part of this volume addresses this important subject. The book is mainly written for students and researchers from evolutionary biology in search for methods to acquire data, but also from molecular biology who might be looking for information on how data are analyzed in an evolutionary context. To aid the user, information on web-located sites is included wherever possible. Approaches that will push the amount of information which systematics will gather in the

Tackling one of the most difficult and delicate of the evolutionary questions, this challenging book summarizes the more recent results in phylogenetics and developmental biology that address the evolution of key innovations in metazoans. Divided into three sections, the first considers the phylogenetic issues involving this area of the tree of life and the elucidation of those relationships that continue to trouble taxonomists. The second section considers the developmental biology of metazoan evolution including the development of the nervous system, sensory organs, and physiological maturation. Part three focuses on the evolution of pattern and process in the Metazoa.

A celebration of beer-its science, its history, and its impact on human culture "Curatorial eminences Rob DeSalle and Ian Tattersall serve up a potent scientific brew. . . . A marvellous paean to the pint, and to the researchers probing its depths."-Barbara Kiser, Nature "Forced to choose between this book and a pint of hazy IPA, I would be at a loss. Better to consume them at the same time-both will go down easily, and leave you in an improved condition."-Bill McKibben What can beer teach us about biology, history, and the natural world? From ancient Mesopotamian fermentation practices to the resurgent American craft brewery, Rob DeSalle and Ian Tattersall peruse the historical record and traverse the globe for engaging and often surprising stories about beer. They explain how we came to drink beer, what ingredients combine to give beers their distinctive flavors, how beer's chemistry works at the molecular level, and how various societies have regulated the production and consumption of beer. Drawing from such diverse subject areas as animal behavior, ecology, history, archaeology, chemistry, sociology, law, genetics, physiology, neurobiology, and more, DeSalle and Tattersall entertain and inform with their engaging stories of beer throughout human history and the science behind it all. Readers are invited to grab a beer and explore the fascinating history of its creation.

"The origin of multicellular animals is one of those difficult and delicate biological problems that have been pondered for centuries. This book summarizes recent results in phylogenetics and developmental biology that address the evolution of key innovations in metazoans. The first section covers phylogenetic issues. Focusing on nervous system and sensory organ development, the second section addresses prominent questions concerning the developmental biology of metazoan evolution. A third section discusses the evolution of pattern and process in the incredible forms of life that we call Metazoa and covers evolution of life histories and the evolution of biogeochemical aspects of metazoans. The book has over 40 illustrations and an up-to-date bibliography of over 500 references. Each chapter concludes with a set of questions for study and discussion."--

Invertebrate Zoology: A Tree of Life Approach is a comprehensive and authoritative textbook adopting an explicitly phylogenetic organization. Most of the classical anatomical and morphological work has not been changed - it established the foundation of Invertebrate Zoology. With the explosion of Next-Generation Sequencing approaches, there has been a sea-change in the recognized phylogenetic relationships among and between invertebrate lineages. In addition, the merger of evolutionary and developmental biology (evo-devo) has dramatically contributed to changes in the understanding of invertebrate biology. Synthesizing these three approaches (classical morphology, sequencing data, and evo-devo studies) offers students an entirely unique perspective of invertebrate diversity. Key Features One of the first textbooks to combine classical morphological approaches and newer evo-devo and Next-Generation Sequencing approaches to address Invertebrate Zoology Organized along taxonomic lines in accord with the latest understanding of invertebrate phylogeny Will provide background in basic systematic analysis useful within any study of biodiversity A wealth of ancillary materials for students and teachers, including downloadable figures, lecture slides, web links, and phylogenetic data matrices

Revolutionary research is revealing how the trillions of microbes living on and in our bodies can keep us healthy . . . or make us sick Suddenly, research findings require a paradigm shift in our view of the microbial world. The Human Microbiome Project at the National Institutes of Health is well under way, and unprecedented scientific technology now allows the censusing of trillions of microbes inside and on our bodies as well as in the places where we live, work, and play. This intriguing, up-to-the-minute book for scientists and nonscientists alike explains what researchers are discovering about the microbe world and what the implications are for modern science and medicine. Rob DeSalle and Susan Perkins illuminate the long, intertwined evolution of humans and microbes. They discuss how novel DNA sequencing has shed entirely new light on the complexity of microbe-human interactions, and they examine the potential benefits to human health: amazing possibilities for pinpoint treatment of infections and other illnesses without upsetting the vital balance of an individual microbiome. This book has been inspired by an exhibition, The Secret World Inside You: The Microbiome, at the American Museum of Natural History, which will open in New York in early November 2015 and run until August 2016. It will then travel to other museums in the United States and abroad.

The human species is very young, but in a short time it has acquired some striking, if biologically superficial, variations across the planet. As this book shows, however, none of those biological variations can be understood in terms of discrete races, which do not actually exist as definable entities. Starting with a consideration of evolution and the mechanisms of diversification in nature, this book moves to an examination of attitudes to human variation throughout history, showing that it was only with the advent of slavery that considerations of human variation became politicized. It then embarks on a consideration of how racial classifications have been applied to genomic studies, demonstrating how individualized genomics is a much more effective approach to clinical treatments. It also shows how racial stratification does nothing to help us understand the phenomenon of human variation, at either the genomic or physical levels.

Revolutionary research is revealing how the trillions of microbes living on and in our bodies can keep us healthy . . . or make us sick Suddenly, research findings require a paradigm shift in our view of the microbial world. The Human Microbiome Project at the National Institutes of Health is well under way, and unprecedented scientific technology now allows the censusing of trillions of microbes inside and on our bodies as well as in the places where we live, work, and play. This intriguing, up-to-the-minute book for scientists and nonscientists alike explains what researchers are discovering about the microbe world and what the implications are for modern science and medicine. Rob DeSalle and Susan Perkins illuminate the long, intertwined evolution of humans and microbes. They discuss how novel DNA sequencing has shed entirely new light on the complexity of microbe-human interactions, and they examine the potential benefits to human health: amazing possibilities for pinpoint treatment of infections and other illnesses without upsetting the vital balance of an individual microbiome. This book has been inspired by an exhibition, The Secret World Inside You: The Microbiome, at the American Museum of Natural History, which will open in New York in early November 2015 and run until August 2016. It will then travel to other museums in the United States and abroad.

Genome sequencing enables scientists to study genes over time and to test the genetic variability of any form of life, from bacteria to mammals. Thanks to advances in molecular genetics, scientists can now determine an animal's degree of inbreeding or compare genetic variation of a captive species to wild or natural populations. Mapping an organism's genetic makeup recasts such terms as biodiversity and species and enables the conservation of rare or threatened species, populations, and genes. By introducing a new paradigm for studying and preserving life at a variety of levels, genomics offers solutions to previously intractable problems in understanding the biology of complex organisms and creates new tools for preserving the patterns and processes of life on this planet. Featuring a number of high-profile researchers, this volume introduces the use of molecular genetics in conservation biology and provides a historical perspective on the opportunities and challenges presented by new technologies. It discusses zoo-, museum-, and herbarium-based biological collections, which have expanded over the past decade, and covers the promises and problems of genomic and reproductive technology. The collection concludes with the philosophical and legal issues of conservation genetics and their potential effects on public policy.

A celebration of beer-its science, its history, and its impact on human culture What can beer teach us about biology, history, and the natural world? From ancient Mesopotamian fermentation practices to the resurgent American craft brewery, Rob DeSalle and Ian Tattersall peruse the historical record and traverse the globe for engaging and often surprising stories about beer. They explain how we came to drink beer, what ingredients combine to give beers their distinctive flavors, how beer's chemistry works at the molecular level, and how various societies have regulated the production and consumption of beer. Drawing from such diverse subject areas as animal behavior, ecology, history, archaeology, chemistry, sociology, law, genetics, physiology, neurobiology, and more, DeSalle and Tattersall entertain and inform with their engaging stories of beer throughout human history and the science behind it all. Readers are invited to grab a beer and explore the fascinating history of its creation.

An imaginative natural history survey of the wide world of spirits, from whiskey and gin to grappa and moonshine In this follow-up book to A Natural History of Wine and A Natural History of Beer, authors Rob DeSalle and Ian Tattersall yet again use alcoholic beverages as a lens through which to gain a greater appreciation of natural history. This volume considers highly alcoholic spirits in the context of evolution, ecology, history, primatology, molecular biology, physiology, neurobiology, chemistry, and even astrophysics. With the help of illustrator Patricia Wynne, DeSalle and Tattersall address historical and cultural aspects and ingredients, the distillation process, and spirits and their effects. They also call on an international group of colleagues to contribute chapters on brandy, vodka, tequila, whiskies, gin, rum, eaux-de-vie, schnapps, baiju, grappa, ouzo, and cachaca. Covering beverages from across the globe and including descriptions of the experience of tasting each drink, this book offers an accessible and comprehensive exploration of the scientific dimensions of spirits.

Ever since the recognition of the Neanderthals as an archaic human in the mid-nineteenth century, the fossilized bones of extinct humans have been used by paleoanthropologists to explore human origins. These bones told the story of how the earliest humans—bipedal apes, actually—first emerged in Africa some 6 to 7 million years ago. Starting about 2 million years ago, the bones revealed, as humans became anatomically and behaviorally more modern, they swept out of Africa in waves into Asia, Europe and finally the New World. Even as paleoanthropologists continued to make important discoveries—Mary Leakey’s Nutcracker Man in 1959, Don Johanson’s Lucy in 1974, and most recently Martin Pickford’s Millennium Man, to name just a few—experts in genetics were looking at the human species from a very different angle. In 1953 James Watson and Francis Crick first saw the double helix structure of DNA, the basic building block of all life. In the 1970s it was shown that humans share 98.7% of their genes with the great apes—that in fact genetically we are more closely related to chimpanzees than chimpanzees are to gorillas. And most recently the entire human genome has been mapped—we now know where each of the genes on the chromosomes that make up DNA is located on the double helix. In Human Origins: What Bones and Genomes Tell Us about Ourselves, two of the world’s foremost scientists, geneticist Rob DeSalle and paleoanthropologist Ian Tattersall, show how research into the human genome confirms what fossil bones have told us about human origins. This unprecedented integration of the fossil and genomic records provides the most complete understanding possible of humanity’s place in nature, its emergence from the rest of the living world, and the evolutionary processes that have molded human populations to be what they are today. Human Origins serves as a companion volume to the American Museum of Natural History’s new permanent exhibit, as well as standing alone as an accessible overview of recent insights into what it means to be human.

It is well established that all humans today, wherever they live, belong to one single species. Yet even many people who claim to abhor racism take for granted that human "races" have a biological reality. In Troublesome Science, Rob DeSalle and Ian Tattersall provide a lucid and forceful critique of how scientific tools have been misused to uphold misguided racial categorizations. DeSalle and Tattersall argue that taxonomy, the scientific classification of organisms, provides an antidote to the myth of race's biological basis. They explain how taxonomists do their science-how to identify a species and to understand the relationships among different species and the variants within them. DeSalle and Tattersall also detail the use of genetic data to trace human origins and look at how scientists have attempted to recognize discrete populations within Homo sapiens. Troublesome Science demonstrates conclusively that modern genetic tools, when applied correctly to the study of human variety, fail to find genuine differences. While the diversity that exists within our species is a real phenomenon, it nevertheless defeats any systematic attempt to recognize discrete units within it. The stark lines that humans insist on drawing between their own groups and others are nothing but a mixture of imagination and ideology. Troublesome Science is an important call for researchers, journalists, and citizens to cast aside the belief that race has a biological meaning, for the sake of social justice and sound science alike.