The design of efficient syntheses of medicinal agents is one of the prime goals of the process chemist in the pharmaceutical industry. The expanding list of metal-mediated reactions has had a major impact on this endeavor over the last two decades. This volume will highlight some of the areas of organometallic chemistry that have played a particularly important role in development. The chapters are written by chemists who work in the process groups of major pharmaceutical companies and fine chemical manufacturers. Having demonstrated the power of organometallics in their processes the authors herein expand upon their experiences with examples from the literature as reported by process groups within the industry. The chapters are organized either by the application of a particular metal or reaction class. Removal of the residual metal(s) from the isolated active pharmaceutical ingredient (API) is key to the release of the material for human consumption, and hence, is reviewed here as well. This volume of Topics in Organometallic Chemistry is presented to offer a representative cross section of organometallic applications in the pharmaceutical industry as well as to give an appreciation for the creativity possible in process chemistry.

The design of efficient syntheses of medicinal agents is one of the prime goals of the process chemist in the pharmaceutical industry. The expanding list of metal-mediated reactions has had a major impact on this endeavor over the last two decades. This volume will highlight some of the areas of organometallic chemistry that have played a particularly important role in development. The chapters are written by chemists who work in the process groups of major pharmaceutical companies and fine chemical manufacturers. Having demonstrated the power of organometallics in their processes the authors herein expand upon their experiences with examples from the literature as reported by process groups within the industry. The chapters are organized either by the application of a particular metal or reaction class. Removal of the residual metal(s) from the isolated active pharmaceutical ingredient (API) is key to the release of the material for human consumption, and hence, is reviewed here as well. This volume of Topics in Organometallic Chemistry is presented to offer a representative cross section of organometallic applications in the pharmaceutical industry as well as to give an appreciation for the creativity possible in process chemistry.

Take the plunge and develop cross-browser-compatible and responsive web designs with SVG Key Features Master the art of custom animations and visualizations with SVG, CSS, and JavaScript Combine SVG with third-party libraries and frameworks such as React, JQuery, D3, and Snap.svg for GUI-rich apps Create an awesome user experience with high-performance graphics for your web applications Book DescriptionSVG is the most powerful image format in use on the web. In addition to producing resolution-independent images for today's multi-device world, SVG allows you to create animations and visualizations to add to your sites and applications. The simplicity of cross-platform markup, mixed with familiar modern web languages, such as CSS and JavaScript, creates a winning combination for designers and developers alike. In this book, you will learn how to author an SVG document using common SVG features, such as elements and attributes, and serve SVG on the web using simple configuration tips for common web servers. You will also use SVG elements and images in HTML documents. Further, you will use SVG images for a variety of common tasks, such as manipulating SVG elements, adding animations using CSS, mastering the basic JavaScript SVG (API) using Document Object Model (DOM) methods, and interfacing SVG with common libraries and frameworks, such as React, jQuery, and Angular. You will then build an understanding of the Snap.svg and SVG.js APIs, along with the basics of D3, and take a look at how to implement interesting visualizations using the library. By the end of the book, you will have mastered creating animations with SVG. What you will learn Deliver the elements that make up an SVG image Replace your old CSS sprites with SVG Understand animation and data visualization with SVG are explained in pure JavaScript and using common libraries Use SVG to scale images across multiple devices easily Harness the power of CSS animations and transformations to manipulate your SVG images in a replicable, remixable way Interface SVG with common libraries and frameworks, such as jQuery, React, and Angular Who this book is forThis book is for web developers and designers looking to add animation to their projects. Some experience with HTML, CSS, and JavaScript is required.

What's the best way to develop for a Web gone wild? That's easy. Simply scrap the rules you've relied on all these years and embrace uncertainty as a core tenet of design. In this practical book, veteran developer Rob Larsen outlines the principles out what he calls The Uncertain Web, and shows you techniques necessary to successfully make the transition. By combining web standards, progressive enhancement, an iterative approach to design and development, and a desire to question the status quo, your team can create sites and applications that will perform well in a wide range of present and future devices. This guide points the way. Topics include: Navigating thousands of browser/device/OS combinations Focusing on optimal, not absolute solutions Feature detection, Modernizr, and polyfills RWD, mobile first, and progressive enhancement UIs that work with multiple user input modes Image optimization, SVG, and server-side options The horribly complex world of web video The Web we want to see in the future

Master HTML and CSS to create modern, stylish, and responsive websites with the help of real-world examples and hands-on activities Key Features Learn HTML and CSS to produce highly functional and appealing websites Overcome common challenges in web design and development Ensure that your websites are accessible and engaging on all devices Book DescriptionWith knowledge of CSS and HTML, you can build visually appealing, interactive websites without relying on website-building tools that come with lots of pre-packaged restrictions. The HTML and CSS Workshop takes you on a journey to learning how to create beautiful websites using your own content, understanding how they work, and how to manage them long-term. The book begins by introducing you to HTML5 and CSS3, and takes you through the process of website development with easy-to-follow steps. Exploring how the browser renders websites from code to display, you'll advance to adding a cinematic experience to your website by incorporating video and audio elements into your code. You'll also use JavaScript to add interactivity to your site, integrate HTML forms for capturing user data, incorporate animations to create slick transitions, and build stunning themes using advanced CSS. You'll also get to grips with mobile-first development using responsive design and media queries, to ensure your sites perform well on any device. Throughout the book, you'll work on engaging projects, including a video store home page that you will iteratively add functionality to as you learn new skills. By the end of this Workshop, you'll have gained the confidence to creatively tackle your own ambitious web development projects. What you will learn Understand how websites are built, structured, and styled Master the syntax and structure of HTML and CSS Know how to build websites from scratch using HTML5 and CSS3 Create intuitive forms that allow users to input data Style your website by integrating videos, animations, and themes Design robust websites that work on all modern devices seamlessly Discover how to maintain and improve the performance of a website Who this book is for Ideal for beginners, this Workshop is designed for anyone who is new to HTML and CSS who wants to learn to design and maintain their own websites.

Everything you need to build websites with the newest versions of HTML and CSS

If you develop websites, you know that the goal posts keep moving, especially now that your website must work on not only traditional desktops, but also on an ever-changing range of smartphones and tablets. This step-by-step book efficiently guides you through the thicket. Teaching you the very latest best practices and techniques, this practical reference walks you through how to use HTML5 and CSS3 to develop attractive, modern websites for today's multiple devices. From handling text, forms, and video, to implementing powerful JavaScript functionality, this book covers it all.Serves as the ultimate beginners guide for anyone who wants to build websites with HTML5 and CSS3, whether as a hobbyist or aspiring professional developerCovers the basics, including the different versions of HTML and CSS and how modern websites use structure and semantics to describe their contentsExplains core processes, such as marking up text, images, lists, tables, forms, audio, and videoDelves into CSS3, teaching you how to control or change the way your pages look and offer tips on how to create attractive designsExplores the jQuery library and how to implement powerful JavaScript features, such as tabbed content, image carousels, and more

Get up to speed on HTML5, CSS3, and today's website design with this practical guide. Then, keep it on your desk as a reference