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This book highlights the role of the Translationally Controlled
Tumor Protein (TCTP) in cell signaling, cell fate and the resulting
connection to disease development. It begins by discussing the
structure/function of TCTP, before exploring its role in different
species ranging from plants to Drosophila and covering fields such
as development, the cytoskeleton, cell division, DNA fragility and
apoptosis. In turn, the book's final section is devoted to the role
of TCTP in disease, namely asthma and diverse cancers, and
ultimately as a target for the treatment of malignancies. What is
the common denominator between all these processes and why is TCTP
necessary in order for them to occur, even in the worst case such
as cancer? The book seeks to provide meaningful answers to this and
other key questions. Presenting a broad and revealing view on the
topic, it offers an informative guide for scientists and students
alike.
This book highlights the role of the Translationally Controlled
Tumor Protein (TCTP) in cell signaling, cell fate and the resulting
connection to disease development. It begins by discussing the
structure/function of TCTP, before exploring its role in different
species ranging from plants to Drosophila and covering fields such
as development, the cytoskeleton, cell division, DNA fragility and
apoptosis. In turn, the book's final section is devoted to the role
of TCTP in disease, namely asthma and diverse cancers, and
ultimately as a target for the treatment of malignancies. What is
the common denominator between all these processes and why is TCTP
necessary in order for them to occur, even in the worst case such
as cancer? The book seeks to provide meaningful answers to this and
other key questions. Presenting a broad and revealing view on the
topic, it offers an informative guide for scientists and students
alike.
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