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Showing 1 - 11 of 11 matches in All Departments

The Sick and His Passenger (Hardcover): Ryan Donnelly The Sick and His Passenger (Hardcover)
Ryan Donnelly
R872 Discovery Miles 8 720 Ships in 10 - 15 working days
Hydrogels - Design, Synthesis and Application in Drug Delivery and Regenerative Medicine (Paperback): Thakur Raghu Raj Singh,... Hydrogels - Design, Synthesis and Application in Drug Delivery and Regenerative Medicine (Paperback)
Thakur Raghu Raj Singh, Garry Laverty, Ryan Donnelly
R1,566 Discovery Miles 15 660 Ships in 12 - 17 working days

Hydrogels are crosslinked, macromolecular polymeric materials arranged in a three-dimensional network, which can absorb and retain large amounts of water. Hydrogels are commonly used in clinical practice and experimental medicine for a wide range of applications, including drug delivery, tissue engineering and regenerative medicine, diagnostics, cellular immobilization, separation of biomolecules or cells, and barrier materials to regulate biological adhesions. This book elucidates the underlying concepts and emerging applications of hydrogels and will provide key case studies and critical analysis of the existing research.

Speaking Thoughts (Paperback): Leta Taylor Speaking Thoughts (Paperback)
Leta Taylor; Edited by Ryan Donnelly; Stewart Sealy
R456 Discovery Miles 4 560 Ships in 10 - 15 working days
Hydrogels - Design, Synthesis and Application in Drug Delivery and Regenerative Medicine (Hardcover): Thakur Raghu Raj Singh,... Hydrogels - Design, Synthesis and Application in Drug Delivery and Regenerative Medicine (Hardcover)
Thakur Raghu Raj Singh, Garry Laverty, Ryan Donnelly
R6,716 Discovery Miles 67 160 Ships in 12 - 17 working days

Hydrogels are crosslinked, macromolecular polymeric materials arranged in a three-dimensional network, which can absorb and retain large amounts of water. Hydrogels are commonly used in clinical practice and experimental medicine for a wide range of applications, including drug delivery, tissue engineering and regenerative medicine, diagnostics, cellular immobilization, separation of biomolecules or cells, and barrier materials to regulate biological adhesions. This book elucidates the underlying concepts and emerging applications of hydrogels and will provide key case studies and critical analysis of the existing research.

Blood Orange Blue (Paperback): Ryan Donnelly Blood Orange Blue (Paperback)
Ryan Donnelly; Illustrated by Patrick McKenna
R459 Discovery Miles 4 590 Ships in 10 - 15 working days
Cochrane is my home (Paperback): Nia Taylor Cochrane is my home (Paperback)
Nia Taylor; Contributions by Ryan Donnelly; Leta Taylor
R375 Discovery Miles 3 750 Ships in 10 - 15 working days
Listen 2 The Future (Paperback): Ryan Donnelly Listen 2 The Future (Paperback)
Ryan Donnelly; Illustrated by Leta Taylor; Stewart Sealy
R456 Discovery Miles 4 560 Ships in 10 - 15 working days
The Unexpected Journey (Paperback): Ryan Donnelly The Unexpected Journey (Paperback)
Ryan Donnelly; Stewart Sealy
R444 Discovery Miles 4 440 Ships in 10 - 15 working days
Words And Nothing More (Paperback): Ryan Donnelly Words And Nothing More (Paperback)
Ryan Donnelly; Illustrated by Paul Anthony; Jonathan Lamoureux Horic
R287 Discovery Miles 2 870 Ships in 10 - 15 working days
The Sick and His Passenger (Paperback): Ryan Donnelly The Sick and His Passenger (Paperback)
Ryan Donnelly
R603 Discovery Miles 6 030 Ships in 10 - 15 working days
Photodynamic Therapy of Vulval Neoplasias and Dysplasias (Paperback): Ryan Donnelly Photodynamic Therapy of Vulval Neoplasias and Dysplasias (Paperback)
Ryan Donnelly
R2,122 Discovery Miles 21 220 Ships in 10 - 15 working days

This book describes the design, physicochemical characterisation and clinical evaluation of bioadhesive drug delivery systems for photodynamic therapy of difficult-to-manage vulval neoplasias and dysplasias. In photodynamic therapy (PDT), a combination of visible light and a sensitising drug causes the destruction of selected cells. ALA is commonly delivered to the vulva using creams or solutions, which are covered with an occlusive dressing to aid retention and enhance drug absorption. Such dressings are poor at staying in place at the vulva, where shear forces are high in mobile patients. To overcome the problems associated with delivery of ALA to the vulva, we produced a bioadhesive patch by a novel laminating procedure. The ALA loading was 38 mg cm-2. Patches were shown to release more ALA over 6 hours than the proprietary cream. The ALA concentration in tissue at 2.375 mm was an order of magnitude greater than that found to be cytotoxic to HeLa cells. Clinically, the patch was used in successful PDT of vulval intraepithelial neoplasia, lichen sclerosus, squamous hyperplasia, Paget's disease and vulvodynia.

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