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Anglo-American Diplomacy and the Palestinian Refugee Problem, 1948-51 (Hardcover): S Waldman Anglo-American Diplomacy and the Palestinian Refugee Problem, 1948-51 (Hardcover)
S Waldman
R2,610 R1,857 Discovery Miles 18 570 Save R753 (29%) Ships in 12 - 17 working days

This volume examines British and US attitudes towards the means and mechanisms for the facilitation of an Arab-Israeli reconciliation, focusing specifically on the refugee factor in diplomatic initiatives. It explains why Britain and the US were unable to reconcile the local parties to an agreement on the future of the Palestinian refugees.

Genetic Recombination - Reviews and Protocols (Hardcover, 2004 ed.): Alan S. Waldman Genetic Recombination - Reviews and Protocols (Hardcover, 2004 ed.)
Alan S. Waldman
R2,818 Discovery Miles 28 180 Ships in 10 - 15 working days

Genetic recombination, in the broadest sense, can be defined as any process in which DNA sequences interact and undergo a transfer of information, producing new "recombinant" sequences that contain information from each of the original molecules. All organisms have the ability to carry out recombination, and this striking universality speaks to the essential role recombination plays in a variety of biological processes fundamentally important to the maintenance of life. Such processes include DNA repair, regulation of gene expression, disease etiology, meiotic chromosome segregation, and evolution. One important aspect of recombination is that it typically occurs only between sequences that display a high degree of sequence identity. The stringent requirement for homology helps to ensure that, under normal circumstances, a cell is protected from deleterious rearrangements since a swap of genetic information between two nearly identical sequences is not expected to dramatically alter a genome. Recombination between dissimilar sequences, which does happen on occasion, may have such harmful consequences as chromosomal translocations, deletions, or inversions. For many organisms, it is also important that recombination rates are not too high lest the genome become destabilized. Curiously, certain organisms, such as the trypanosome parasite, actually use a high rate of recombination at a particular locus in order to switch antigen expression continually and evade the host immune system effectively.

Genetic Recombination - Reviews and Protocols (Paperback, Softcover reprint of hardcover 1st ed. 2004): Alan S. Waldman Genetic Recombination - Reviews and Protocols (Paperback, Softcover reprint of hardcover 1st ed. 2004)
Alan S. Waldman
R2,787 Discovery Miles 27 870 Ships in 10 - 15 working days

Genetic recombination, in the broadest sense, can be defined as any process in which DNA sequences interact and undergo a transfer of information, producing new "recombinant" sequences that contain information from each of the original molecules. All organisms have the ability to carry out recombination, and this striking universality speaks to the essential role recombination plays in a variety of biological processes fundamentally important to the maintenance of life. Such processes include DNA repair, regulation of gene expression, disease etiology, meiotic chromosome segregation, and evolution. One important aspect of recombination is that it typically occurs only between sequences that display a high degree of sequence identity. The stringent requirement for homology helps to ensure that, under normal circumstances, a cell is protected from deleterious rearrangements since a swap of genetic information between two nearly identical sequences is not expected to dramatically alter a genome. Recombination between dissimilar sequences, which does happen on occasion, may have such harmful consequences as chromosomal translocations, deletions, or inversions. For many organisms, it is also important that recombination rates are not too high lest the genome become destabilized. Curiously, certain organisms, such as the trypanosome parasite, actually use a high rate of recombination at a particular locus in order to switch antigen expression continually and evade the host immune system effectively.

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