Anti-Aging Drug Discovery on the Basis of Hallmarks of Aging is a comprehensive and timely book on all aspects of anti-aging strategies. The book provides comprehensive, foundational knowledge on the mechanisms of aging and current anti-aging strategies and approaches developed. Aging research has experienced an unprecedented advance over recent years with the discovery that the rate of aging is determined, at least to some extent, mainly by our genetics and modulated by environmental factors. The hallmarks of aging describe the molecular and cellular processes that govern biological aging and their variation in individuals.

This book comprises chapters on research work done around the globe in the area of artificial intelligence (AI) applications in sheet metal forming. The first chapter offers an introduction to various AI techniques and sheet metal forming, while subsequent chapters describe traditional procedures/methods used in various sheet metal forming processes, and focus on the automation of those processes by means of AI techniques, such as KBS, ANN, GA, CBR, etc. Feature recognition and the manufacturability assessment of sheet metal parts, process planning, strip-layout design, selecting the type and size of die components, die modeling, and predicting die life are some of the most important aspects of sheet metal work. Traditionally, these activities are highly experience-based, tedious and time consuming. In response, researchers in several countries have applied various AI techniques to automate these activities, which are covered in this book. This book will be useful for engineers working in sheet metal industries, and will serve to provide future direction to young researchers and students working in the area.

Cementitious materials, rocks and fibre-reinforced composites commonly termed as "quasibrittle," need a different fracture mechanics approach to model the crack propagation study because of the presence of significant size of fracture process zone ahead of the crack-tip. Recent studies show that concrete structures manifest three important stages in fracture process: crack initiation, stable crack propagation and unstable fracture or failure. Fracture Mechanics concept can better explain the above various stages including the concepts of ductility, size-effect, strain softening and post-cracking behavior of concrete and concrete structures.

The book presents a basic introduction on the various nonlinear concrete fracture models considering the respective fracture parameters. To this end, a thorough state-of-the-art review on various aspects of the material behavior and development of different concrete fracture models is presented. The development of cohesive crack model for standard test geometries using commonly used softening functions is shown and extensive studies on the behavior of cohesive crack fracture parameters are also carried out. The subsequent chapter contains the extensive study on the double-"K" and double-"G" fracture parameters in which some recent developments on the related fracture parameters are illustrated including introduction of weight function method to Double-"K" Fracture Model and formulization of size-effect behavior of the double-"K" fracture parameters. The application of weight function approach for determining of the "KR"-curve associated with cohesive stress distribution in the fracture process zone is also presented. Available test data are used to validate the new approach. Further, effect of specimen geometry, loading condition, size-effect and softening function on various fracture parameters is investigated. Towards the end, a comparative study between different fracture parameters obtained from various models is presented."

Cementitious materials, rocks and fibre-reinforced composites commonly termed as quasibrittle, need a different fracture mechanics approach to model the crack propagation study because of the presence of significant size of fracture process zone ahead of the crack-tip. Recent studies show that concrete structures manifest three important stages in fracture process: crack initiation, stable crack propagation and unstable fracture or failure. Fracture Mechanics concept can better explain the above various stages including the concepts of ductility, size-effect, strain softening and post-cracking behavior of concrete and concrete structures. The book presents a basic introduction on the various nonlinear concrete fracture models considering the respective fracture parameters. To this end, a thorough state-of-the-art review on various aspects of the material behavior and development of different concrete fracture models is presented. The development of cohesive crack model for standard test geometries using commonly used softening functions is shown and extensive studies on the behavior of cohesive crack fracture parameters are also carried out. The subsequent chapter contains the extensive study on the double-K and double-G fracture parameters in which some recent developments on the related fracture parameters are illustrated including introduction of weight function method to Double-K Fracture Model and formulization of size-effect behavior of the double-K fracture parameters. The application of weight function approach for determining of the KR-curve associated with cohesive stress distribution in the fracture process zone is also presented. Available test data are used to validate the new approach. Further, effect of specimen geometry, loading condition, size-effect and softening function on various fracture parameters is investigated. Towards the end, a comparative study between different fracture parameters obtained from various models is presented.

This book presents the selected proceedings of 2nd International Conference on Recent Advances in Manufacturing (RAM 2021). The book provides insights to current research trends and opportunities in modelling and optimization of manufacturing processes and systems. The topics covered include modelling analysis, computing and simulation, traditional and non-traditional optimization techniques, surface coating methods, additive manufacturing processes, CAD/CAM, robotics and automation, welding and joining processes, supply chain management and CAE and reverse engineering. This book will be a good reference for beginners, researchers and professionals interested in modelling and optimization related to manufacturing engineering and related fields.

The book presents the select proceedings of National Conference on Recent Advances in Structural Engineering (NCRASE 2020). Various topics covered in this book include advanced structural materials, computational methods of structures, earthquake resistant analysis and design, analysis and design of structures against wind loads, pre-stressed concrete structures, bridge engineering, experimental methods and techniques of structures, offshore structures, composite structures, smart materials and structures, port and harbor structures, structural dynamics, high rise structures, sustainable materials in the construction technology, advanced structural analysis, extreme loads on structures, innovative structures, and special structures. The book will be useful for researchers and professional working in the field of structural engineering.

This book presents the select proceedings of the International Conference on Recent Advances in Manufacturing (RAM 2020). The volume focuses on latest research trends in manufacturing systems such as CAE, CAD/CAM, robotics and automation, reverse engineering, resource planning and simulation, computer-integrated manufacturing (CIM) systems, product life-cycle management, collaborative engineering, process monitoring control and traceability technologies, supply chain management, environment risk analysis, and manufacturing systems of renewable energy devices. The topics covered also include emerging fields of the fourth industrial revolution such cyber physical systems and cyber security, and wireless sensors and sensor networks for manufacturing. This book will be of interest to researchers and practitioners interested in latest developments in the field of manufacturing systems.

This book comprises chapters on research work done around the globe in the area of artificial intelligence (AI) applications in sheet metal forming. The first chapter offers an introduction to various AI techniques and sheet metal forming, while subsequent chapters describe traditional procedures/methods used in various sheet metal forming processes, and focus on the automation of those processes by means of AI techniques, such as KBS, ANN, GA, CBR, etc. Feature recognition and the manufacturability assessment of sheet metal parts, process planning, strip-layout design, selecting the type and size of die components, die modeling, and predicting die life are some of the most important aspects of sheet metal work. Traditionally, these activities are highly experience-based, tedious and time consuming. In response, researchers in several countries have applied various AI techniques to automate these activities, which are covered in this book. This book will be useful for engineers working in sheet metal industries, and will serve to provide future direction to young researchers and students working in the area.

This book contains select proceedings of EPREC-2021 with a focus on power electronics and drives. The book includes original research and case studies that present recent developments in power electronics focusing on power inverters and converters. The book also consists of research work on electrical drives, regulated power supplies, operation of FACTS & HVDC, etc. The book will be a valuable reference guide for beginners, researchers, and professionals interested in the advancements of power electronics and drives.