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Circadian Rhythms and Their Impact on Aging (Hardcover, 1st ed. 2017): S Michal Jazwinski, Victoria P Belancio, Steven Hill Circadian Rhythms and Their Impact on Aging (Hardcover, 1st ed. 2017)
S Michal Jazwinski, Victoria P Belancio, Steven Hill
R5,171 Discovery Miles 51 710 Ships in 10 - 15 working days

Biological rhythms time the ebb and flow of virtually every physiological process, and their mutual coordination guarantees the integrity of the organism over space and time. Aging leads to the disintegration of this coordination, as well as to changes in the amplitude and/or frequency of the underlying rhythms. The results of this are accelerated loss of health during aging, and in experimental model systems curtailed lifespan occurs. This book will examine the machinery that constitutes circadian systems and how they impact physiologic processes. It will also discuss how disturbances of circadian rhythms can lead to complex diseases associated with aging. Much of this treatment will focus on metabolism and genome stability. Importantly, the chapters in this book will encompass work in several different models, in addition to human. The book will conclude with a discussion of modeling approaches to biologic cycles and chronotherapy, for future research and translation.

Circadian Rhythms and Their Impact on Aging (Paperback, Softcover reprint of the original 1st ed. 2017): S Michal Jazwinski,... Circadian Rhythms and Their Impact on Aging (Paperback, Softcover reprint of the original 1st ed. 2017)
S Michal Jazwinski, Victoria P Belancio, Steven M Hill
R6,113 Discovery Miles 61 130 Ships in 10 - 15 working days

Biological rhythms time the ebb and flow of virtually every physiological process, and their mutual coordination guarantees the integrity of the organism over space and time. Aging leads to the disintegration of this coordination, as well as to changes in the amplitude and/or frequency of the underlying rhythms. The results of this are accelerated loss of health during aging, and in experimental model systems curtailed lifespan occurs. This book will examine the machinery that constitutes circadian systems and how they impact physiologic processes. It will also discuss how disturbances of circadian rhythms can lead to complex diseases associated with aging. Much of this treatment will focus on metabolism and genome stability. Importantly, the chapters in this book will encompass work in several different models, in addition to human. The book will conclude with a discussion of modeling approaches to biologic cycles and chronotherapy, for future research and translation.

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