This edition of the SAGES Manual of Hernia Surgery aligns with the current version of the new SAGES University MASTERS Program Hernia Surgery pathway. This manual serves as a curriculum for participants in the MASTERS Program as well as a modern text on hernia surgery for all learners. Hernia surgery is one of the fastest developing fields in general surgery today. There have been rapid advancements in hernia techniques in recent years, making most prior texts on the subject obsolete. These advancements involve significant evolution in both the techniques and strategies for hernia repairs, as well as the tools used to achieve these means. This text thoroughly addresses the multiple component separation techniques and options for locations of mesh repairs. It also discusses the revolution of hernia repair being facilitated by robotic surgery, which allows increased access to minimally invasive techniques for surgeons and thus increased access to minimally invasive surgical repairs for patients. This manual will be a valuable resource for interested surgeons to understand the variety of potential approaches to individual hernias, and to individually tailor the care of the hernia patient.

Discover a unique toolkit of science, self-compassion and intuitive eating practices to help you understand, love and heal your gut. Living with gut problems means it can feel like our insides are working against us, but have you ever taken a moment to really listen to your gut? Inspired by her own healing journey, expert patient Cara Wheatley-McGrain has developed a revolutionary approach to thriving with IBS and IBD through understanding, loving and listening to your gut. As Cara shares her tried-and-tested methods, you'll be empowered to create your own unique gut-led journey based on science, self-compassion and intuitive eating. You'll discover an extensive toolkit of exercises and strategies designed to calm your gut and support you wellbeing at every level. Cara shares how to: * get to know your unique gut microbiome and microbes * cultivate compassion, self-care and greater connection with your gut * use simple techniques for a calmer and more mindful lifestyle * develop intuitive eating practices and a diet that suits you * create fresh, healthy and delicious recipes for every mealtime When you start to truly listen to your gut - in a deeply powerful, gut-loving way - it will change your life.

Appendicitis remains one of the most common surgical emergencies, with approximately 200,000 annual cases in the United States and a lifetime risk of 8%. The treatment of appendicitis has evolved significantly, from the first reported appendectomy in 1736 at St. George's Hospital in London. This book discusses several topics on appendicitis including the surgical management of appendicitis; pediatric advanced appendicitis; acute appendicitis; treatment strategies; risk factors and clinical implications.

There are not many books published about esophageal cancer. Esophageal cancer is an entity that must be treated from a multimodal approach. Recent advances in diagnosis, anesthetic aspects and perioperative care, among others, are summarized in this book. This book is written in a simple way and intends to cover the main aspects of this type of cancer. It incorporates the latest evidence about the diagnosis, management and treatment of esophageal cancer from a multimodal point of view. Epidemiologists, gastroenterologists, oncologists and surgeons have all participated in the elaboration of this book. It is divided into ten chapters, describing all esophageal cancer topics and each chapter has been written by recognized experts in this field. Complex content and results have been made reader-friendly and easily understandable. This book is especially useful for residents and fellows because it highlights the important principles for managing these patients. The chapter about surgery is written by a surgeon who is currently considered the best in esophageal cancer, Prof. Simon Law. Also, the oncological content has been written highlighting the latest practical and clinical evidence. The reader can use this book as a practical guideline when addressing patients with esophageal cancer.

New Concepts in the Management of Septic Perianal Conditions provides a comprehensive review of the medically important basic and clinical aspects of perianal diseases in adults. This book presents current, medically important information in the rapidly changing field of anorectal diseases, including significant topics like perianal abscess and fistula. It provides an accurate source of clinically relevant information that is presented clearly and succinctly, making it perfect for the diagnosis, treatment and management of septic perianal conditions.

Physiology of the Gastrointestinal Tract, Sixth Edition, a Two-Volume set, covers the study of the mechanical, physical and biochemical functions of the GI Tract by linking clinical disease and disorder, thus bridging the gap between clinical and laboratory medicine while also covering breakthroughs in gastroenterology, such as the brain-gut axis and microbiome. Additionally, information is provided at the organism level, including animal models of gastrointestinal disorders and therapeutic possibilities. The book covers a wide range of conditions, from food allergies, constipation, chronic liver disease and IBS, also exploring emerging techniques to diagnose and normalize functions of the GI tract. As a highly referenced book, this is a useful resource for gastroenterologists, physiologists, internists, professional researchers and instructors teaching courses for clinical and research students.

Standardizing Pharmacology: Assays and Hormones, Volume Two in the Discoveries in Pharmacology series, presents selected articles from historic discoveries that are enhanced with commentary from contemporary scholars who present discussions on the importance of each chapter, along with an updated bibliography on the subject and contributions from a Nobel Prize winner and other pioneers in pharmacology. Academic and industry researchers in pharmacology and medicine, as well as advanced students will find this series a useful teaching tool and launch to new discoveries. Sections cover key discoveries in receptor theory, pharmacological methods and the development of hormone therapy, including J. Parascandola on the development of receptor theory, R.S. Yalow on radioimmunoassay, M. van Rossum and J.T L.A. Hurkmans on bioassays, M. Tausk on androgen therapy and C. Djerassi on oral contraceptives, with commentaries from experts such as T. Hoekfelt and V.C. Jordan.

We know that gut health is key to our wellbeing so it's high time we break the taboos and get familiar with our poo!

In Regular, digestive health expert and medical nutritionist Tamara Duker Freuman tackles this less than glamorous topic and teaches you all you need to know about your bowel health. Offering tailored solutions for the most common - and uncommon - issues, including irritable bowel syndrome, reflux and Coeliac disease, this book will guide readers to identify the specific cause of their irregularity and provide personalised solutions and tips, including: questions to take to your next doctor's visit; an interactive quiz that will help you identify the quality of your stool; tables and charts listing problematic foods and suggested alternatives; sample menus, and more.

Whether you or a loved one suffers from chronic diarrhoea or constipation, Regular covers the most common causes of bowel irregularity with detailed descriptions of their presentations that a sufferer should recognise, including:

• fructose, lactose, and sucrose intolerances
• histamine intolerance
• inflammatory bowel diseases (IBD), such as Crohn's disease and ulcerative colitis
• irritable bowel syndrome (IBS)
• malabsorptive conditions, such as bile acid malabsorption (BAM), celiac disease, pancreatic insufficiency, and small intestinal bacterial overgrowth (SIBO) and
• pelvic floor dysfunction

This revised and updated second edition of the popular and comprehensive guide to the study of gastroenterology The revised second edition of Essentials of Gastroenterology provides a highly practical and concise guide to gastroenterology. The text covers every major disorder likely to be encountered during both GI training and in clinical practice. It also offers a handbook for preparing for Board examinations (e.g., USMLE and Internal Medicine Board examinations) as well as a handy clinical consultation tool. Fully updated to reflect the latest scientific information and practice guidelines, each section of the book covers a specific area of the gastroenterology tract and follows a standard outline: general information, normal physiology, etiology and pathophysiology, clinical presentation, diagnosis, differential diagnosis, complications, prognosis, and treatment. The text provides easy-to-assimilate information on each disorder and includes the key facts, concise, bulleted paragraphs, and a structure that lends itself to accessibility and point-of-care use in a busy clinical setting. In addition, Internal Medicine Board-style multiple choice questions allow users to self-assess their knowledge, a photo gallery provides a great visual element, and clinical cases throughout allow readers to identify with real-life clinical scenarios. Essentials of Gastroenterology is the hands-on guide that: - Covers the whole of gastroenterology in one highly practical volume - Presents updated pedagogic features to help achieve rapid clinical understanding, such as case studies, practice points, key weblinks and potential pitfalls boxes - Includes more than 100 Internal Medicine Board-style multiple choice questions ideal for self-assessment - Contains comparison of major society (BSG, ASG, ACG, UEGF, etc.) guidelines for all main GI conditions Designed for us by gastroenterologists and GI trainees, Essentials of Gastroenterology is therevised and improved edition of the popular manual that is filled with up-to-date information on all the GI disorders. Trainees will learn the essentials of their specialty, as well as providing the seasoned gastroenterologist with a useful refresher tool.

The book offers a comprehensive review of the relations between volumes and outcomes in oncological surgery especially in Italian hospitals, based on national and regional data. After illustrating the quality-control methodology and the determinants of surgical outcomes, it discusses the volume-outcome relationship in different fields of surgical oncology (cancers of the upper and lower gastrointestinal tract, hepatopancreatobiliary system, breast, sarcomas etc.) and suggests possible solutions. The latest findings from Europe and the USA are also presented.

This issue details the latest knowledge of early diagnosis, risk factors, limited surgical treatments, and novel therapies for pancreatic diseases. Clinicians will learn the most prognostic scoring systems for acute pancreatitis, review the basics for early management of the disease, and see how current practice guidelines have evolved. Advances in radiological imaging when applied to the pancreas have resulted in enhanced staging and improved selection for surgical intervention. Endoscopy of the pancreas via both ERCP and endoscopic ultrasound has led to unprecedented access and potential for non-operative intervention. Pancreatic surgery now takes advantage of both minimally invasive approaches and techniques learned from organ transplantation. These latest advances are addressed in this issue by key opinion leaders.

Now fully revised to include recent advances in the field, the third edition of Gastrointestinal and Liver Pathology Pathology, a volume in the Foundations in Diagnostic Pathology series, is an essential foundation text for residents and pathologists. The popular template format makes it easy to use, and new information throughout brings you up to date with what's new in the field, including advances in molecular diagnostic testing and new diagnostic biomarkers. Practical and affordable, this resource is ideal for study and review as well as everyday clinical practice.Key features of this practical text include:  A consistent, user-friendly format that explores each entity's clinical features, gross and microscopic findings, ancillary studies, differential diagnoses, and prognostic and therapeutic considerations.  A focus on specific features of selected neoplastic and non-neoplastic entities, including broad and in-depth differential diagnoses.  Clinical information on treatment and prognosis, enabling you to better understand the clinical implications of the diagnosis.  Nearly 1,000 full-color, high-quality illustrations with extensive figure legends, as well as abundant boxes and tables throughout.  Enhanced eBook version included with purchase. Your enhanced eBook allows you to access all of the text, figures, and references from the book on a variety of devices.  What's NEW in this edition:  Advances in molecular diagnostic testing and its capabilities and limitations, including targeted/personalized medicine.  New diagnostic biomarkers and their utility in differential diagnosis, newly described variants, and new histologic entities.  The latest TNM staging and WHO classification systems.  New co-editors Drs. Amitabh Srivastava and Daniela S. Allende lead a team of expert, internationally recognized pathologists who keep you up to date with the latest information in the field. 

Gastric cancer is one of the leading causes of malignancy-related deaths world-wide with differences in incidence and treatment patterns geographically. There is extensive ongoing research for a better understanding of the cancer pathology and finding newer treatments. Advancements in basic science research are being translated for improving gastric cancer patient care. This book discusses an extensive array of different topics on gastric cancer in which strides of improvement have been achieved. The contributors of each specialised chapter of the book are leaders in their field and have been recognised for their work globally. This book aims to bring the readers up to date about all aspects of gastric cancer - from basic science research about animal models of gastric cancer, to pathophysiology, staging systems, different adjuvant therapies and surgical treatment options for gastric cancer. The newer treatment options of endoscopic mucosal resections and bursectomy are described in detail. The current statuses, debates and ongoing controversies in addition to the advancements on different aspects of gastric cancer research are discussed. The book is an invaluable resource of information on all aspects of gastric cancer with the latest advancements.

The Liver in Systemic Disease A practical guide for non-hepatologists who encounter abnormal liver test results in patients The Liver in Systemic Disease is an easy-to-use and authoritative guide for non-hepatologist health care professionals who need guidance on the management of patients with abnormal liver tests. The book provides definitive advice for when further investigation, or changes in management, are indicated. With a practical focus throughout the text, the editors explore when and how to investigate and manage patients whose primary disease is non-hepatic, but whose liver tests are unexpectedly abnormal. The Liver in Systemic Disease provides substantial flow diagrams and advice on the process, together with updates on the liver diseases non-hepatologists are most likely to encounter. Take-home primers included in the book shine a light on best practice and recommended procedures when dealing with abnormal liver test results. The book also provides: A thorough introduction to evaluate the liver, including serum liver tests, liver imaging, and liver biopsy Comprehensive discussions of practical issues in patients with liver abnormalities, including the diagnosis of drug induced liver injury, prescribing in patients with abnormal liver tests, and more Practical discussions of the management of patients with unexplained abnormal liver tests in primary care In-depth examinations of secondary care management of patients with unexplained abnormal liver tests, including intensive care, and the care of infectious and immunosuppressed patients The Liver in Systemic Disease is an indispensable resource for non-hepatologist medical practitioners seeking to understand the implications of abnormal liver tests and who wish to know when further investigation or alteration of management is indicated.

Upper Digestive Tract, 2nd Edition, part 1 in the 3-book Digestive System volume, provides a concise and highly visual approach to the basic sciences and clinical pathology of the mouth, pharynx, esophagus and stomach. This book in The Netter Collection of Medical Illustrations (the CIBA "Green Books") has been expanded and revised to capture current perspectives in gastroenterology - from normal anatomy and physiology through pathophysiology, diagnostics and treatment. Radiologic and pathologic images supplement the classic Netter illustrations, as well as new illustrations. Highlights include neurophysiology and electrical physiology of normal gastric function and disease, Barrett's esophagus, eosinophilic esophagus, and imaging and physiologic complexities of swallowing. Gain a rich, comprehensive overview of the upper digestive tract by seeing classic Netter illustrations side by side with cutting-edge radiologic and endoscopic images. Explore key topics in gastroenterology, including tumors of salivary glands, microbiota, diagnostic aids, and postgastrectomy complications. See modern issues in digestive health and disease (bariatric surgery, IBS, and GERD) captured in the visually rich Netter artistic tradition via contributions from artists working in the Netter style. Get complete, integrated visual guidance on the mouth, pharynx, esophagus and stomach in a single source, from basic sciences and normal anatomy and function through pathologic conditions. Benefit from the knowledge of a team of renowned clinicians and scientists.

Liver, Biliary Tract and Pancreas, 2nd Edition, part 3 in the 3-book Digestive System volume, provides a concise and highly visual approach to the basic sciences and clinical pathology of the hepatobiliary system and pancreas. This book in The Netter Collection of Medical Illustrations (the CIBA "Green Books") has been expanded and revised to capture current perspectives in hepatology, pancreatology, and gastroenterology - from normal anatomy and physiology through pathophysiology, diagnostics and treatment of the liver, pancreas, and biliary tract. It also features radiologic and pathologic images to supplement the classic Netter illustrations, as well as new illustrations. This this updated classic is ideal for students and health professionals seeking an easily accessible guide to the digestive system. Put concepts into practice. An exquisite art program that focuses on clarity of presentation with an emphasis on anatomy, pathology, patient presentation, and clinical context. Gain a rich, comprehensive overview of the liver, pancreas and biliary tract by seeing classic Netter illustrations side by side with cutting-edge radiologic and laparoscopic images. Explore key topics, including tumors of cirrhosis, portal hypertension, pancreatitis, liver lobectomy and transplantation, and cholescystectomy. See modern issues in digestive health and disease captured in the visually rich Netter artistic tradition via contributions from artists working in the Netter style. Get complete, integrated visual guidance on the hepatobiliary system and pancreas in a single source, from basic sciences and normal anatomy and function through pathologic conditions. Benefit from the knowledge of a team of renowned clinicians and scientists.

Advocate For Your Care It's expected that you will have questions about biliary cancer upon diagnosis. Whether it's your own diagnosis or a diagnosis of a loved one, this easy-to-read guide provides invaluable practical knowledge such as help for preparing to meet with an oncologist, seeking a second opinion, and understanding clinical trials. 100 Questions & Answers About Cholangiocarcinoma, Gallbladder, and Bile Duct Cancers is a resource that empowers patients and caregivers with the information needed to navigate their treatment with realistic goals for a good quality of life and targeted long-term survivorship. The perspective of patients and doctors is provided in this book with comprehensive answers to the most asked questions with added guidance for support and access to support services. You are the best solution to your cancer care.

Upper gastrointestinal bleeding is the leading emergency leading to hospitalization and urgent endoscopy. The field of gastrointestinal bleeding is rapidly evolving. The epidemiology is changing with more complex older patients on anticoagulant and antithrombotic agents presenting with upper gastrointestinal bleeding. The initial management has rapidly evolved with new transfusion thresholds, the use of risk stratification scores and no more nasogastric tubes. There is new data and recommendations on optimal timing of endoscopy. Medical therapies have also evolved with changes in proton pump inhibitor administration and the use of prokinetics to improve endoscopic visualization. Many modifications in endoscopic therapy have recently been advanced including the use of endoscopic ultrasound guided angiotherapy, topical sprays (i.e. Hemospray) and over-the-scope clips. In order to give optimal care to patients, it is critical that practicing gastroenterologists are aware of the many recent advances in management of patients with upper gastrointestinal bleeding.

This textbook on the digestive system was developed in collaboration with medical students to meet both students' and teachers' needs and objectives. It is currently the official gastroenterology textbook for undergraduate students in all French medical schools in Canada, and is also used in Europe and Africa. An updated and improved 3rd edition was published in French in 2020; this translation and update make the book available in English for the first time. The text features contributions from GI experts from Quebec, France, French Africa, and from key Canadian GI experts.The first part of the book covers the eight main organs of the digestive system, while the second half discusses the major clinical diseases and symptoms that affect the digestive system. This book is comprehensive and well-organized, and features color-coded and beautifully designed figures and tables that make the book helpful and accessible to students.

Intestinal transplantation remains on the cutting edge of solid organ transplantation. Each potential recipient provides a unique case of intestinal failure with individual intricacies requiring the combined efforts of a complex multidisciplinary team in order to achieve success. Contemporary Small Bowel Transplantation covers all aspects of intestinal transplantation in a manner accessible to all providers and provides specific guidance for those that may come in contact with this field and these patients. The text provides an understanding of the critical pre-operative evaluation, thorough descriptions of each surgical procedure and postoperative management. Areas such as infectious disease, nutrition and graft versus host disease will be addressed in detail. Key controversies and administrative issues unique to intestinal transplantation are covered. Contemporary Small Bowel Transplantation provides critical guidance for the new transplant surgeon, gastroenterologist or administrator as they navigate the challenging field of intestinal transplantation.

This issue of Hematology/Oncology Clinics of North America, devoted to Colorectal Cancer, is edited by Dr. Leonard B. Saltz. Articles in this issue include: Diet and Lifestyle Influences on Colorectal Cancer; Diagnosis and Management of Germline and Somatic Mutations in Mismatch Repair-deficient Colorectal Cancer; Adjuvant Chemotherapy in Stage II, III, and Resected Stage IV Colon Cancer; Predictive and Prognostic Markers in the Treatment of Colorectal Cancer; Surgical Management of Hepatic Metastases of Colorectal Cancer; Combination Therapies in Colorectal Cancer Treatment; A Critical Look at Management of Peritoneal Metastases of Colorectal Cancer; Non-surgical Management of Rectal Cancer; and Ablative Therapies for Metastatic Colorectal Cancer.

"Celiac Disease and Gluten: Multidisciplinary Challenges and Opportunities" is a unique reference work the first to integrate the insights of the causes and effects of celiac disease from the chemistry of reaction-causing foods to the diagnosis, pathogenesis, and symptoms that lead to proper diagnoses and treatment. With an estimated three million people in the United States alone affected by celiac disease, an autoimmune digestive disease, onlyfive percentare properly diagnosed. Drawing on the connection between foods containing gluten and the resulting symptoms, this resource offers distinctive information that directly explores and links food science, medical diagnostics, and treatment information. A helpful tool for researchers and medical practitioners alike, "Celiac Disease and Gluten: Multidisciplinary Challenges and Opportunities" helps refine research targets, and provides a comprehensive overview on the multidisciplinary approaches to all crucial aspects related to celiac disease.
Presents key information from medical and food science research, as well as provides clinical insightsProvides direct corollary insights between source and symptomWritten by experts whose detailed experiments and results have shaped our understanding of celiac disease"

Diet and Exercise in Cystic Fibrosis, a unique reference edited by distinguished and internationally recognized nutritionist and immunologist Ronald Ross Watson, fills the gap in the current dietary modalities aimed at controlling cystic fibrosis. Using expert evaluation on the latest studies of the role of food and exercise in lifelong management of cystic fibrosis, this valuable resource shows how to maintain intestinal, hepatic, and pulmonary high quality function for improving quality of life for those with cystic fibrosis. A helpful tool for researchers and clinicians alike, this reference helps refine research targets, and provides the beginning of a structured dietary management scheme for those with cystic fibrosis.