Schizophrenia remains a poorly understood and yet a profoundly serious condition among all the major medical illnesses. A major shift in the past 5 years has been witnessed among psychiatrists with the belief now that diagnosis and intervention early may have a positive influence on the outcome of schizophrenia. This shift has led to searching for key diagnostic clusters to enhance early diagnosis as well as to concerted efforts to find biomarkers of disease and disease progression. To that end, this issue of the Psychiatric Clinics of North America is dedicated to these contemporary issues that promote 'early intervention' in schizophrenia. Distinguished academic clinicians and neuroscientists provide comprehensive overviews of the present state of knowledge on the epidemiology, early clinical characteristics, and diagnostic changes, proposed pathogenesis, neurobiology, and treatment requirements for this disorder. The optimism and excitement for real progress in schizophrenia research treatment is incorporated into this text. The current state of knowledge is substantial, academically credible, and scientifically based. Topics on the subject of early intervention in and diagnosis of schizophrenia include: The Nosology of Schizophrenia: Defining Illness Boundaries Based upon Symptoms; The Neurodevelopmental Hypothesis of Schizophrenia: a Critical Synthesis; Predicting Risk and the Emergence of Schizophrenia; Is Early Intervention for Psychosis Feasible and Effective?; Can Neuroimaging Be Used to Define Phenotypes and Course of Schizophrenia?; Reliable Biomarkers and Predictors of Schizophrenia and Its Treatment; From Study to Practice: Enhancing Clinical Trials Methods Toward 'Real World' Outcomes; Relapse Prevention in Schizophrenia; Antipsychotic Polypharmacy: Every Clinician's 'Dirty Little Secret'; Cognitive Remediation: Retraining the Brain in Schizophrenia; Peers and Peer-led Interventions; Homelessness; and The Emerging Role of Technology and Social Media in Caring for People with Schizophrenia. Each presentation in this publication includes an Overview, Implications for Practice, with Summarizations of Important Clinical and Learning Points.

Psychopharmacology is a dominant treatment in child and adolescent psychiatry with proven benefits to young patients. The authors present topics related to PSYCHOPHARMACOLOGY ISSUES: Ethical issues, Treatment planning, Side effects, Neural correlates, and Pharmacogenomics. They address DRUGS FOR SPECIFIC DISEASES: Anxiety, Depression, Eating disorders, Sleep disorders, Psychosis and Schizophrenia, High-risk for bilpolar and schizophrenia, Bipolar, ADHD, and Autism. Each topic presents an Overview of the Disease or Issue, Empirical evidence for ethical issues, Treatment summaries that include dose ranges, side effects, contraindications, and how the drugs are used specifically for a disorder. Treatment in the presence of co-morbid conditions, Long-term evidence, and Conclusions and Future directions complete the presentations. Clinical vignettes are provided that exemplify the main points of the topic.

The Year Book of Psychiatry and Applied Mental Health brings you abstracts of the articles that reported the year's breakthrough developments in psychiatry and mental health, carefully selected from more than 300 journals worldwide. Expert commentaries evaluate the clinical importance of each article and discuss its application to your practice. There's no faster or easier way to stay informed! Annual topics feature the latest information on biological psychiatry, alcohol and substance-related disorders, psychiatry and the law, psychotherapy, and clinical psychiatry.

This subject, written for psychiatrists, is of importance and relevance to psychiatrists dealing with apsects of the practice that cross with legal professionals and with school and corporate professionals. This subject of Forensic Psychiatry presents topics on: Psychopharmacologic treatment of aggression; Assessment of blackouts and claimed amnesia; Forensic assessment of bullying; Testamentary capacity and guardianship assessments; Psychological testing and the assessment of malingering; Child murder by parents; Mass murderers: who are they and how might we stop them?; Child pornography and the Internet; Do's and don'ts of depositions; Juvenile offenders: Updates on competency and culpability; The role of the forensic psychiatrist in the immigration process; and Psychiatric Management of the Problematic Employee. The topics are presented to include coverage of Nature and Definition of the Problem, Physical Examination, Evaluation, Competency Evaluation, Clinical Assessment Strategies, Psychiatric Testing Strategies, Reaching an Opinion, with Key Points of every topic.

Anxiety disorders are common in children and adolescents and can be debilitating if not recognized and treated. This issue covers the landscape of anxiety disorders in youth, from development and neurobiology; to treatments, advances, and novel approaches; to informing other systems of care: primary physicians, schools, and parents. Specific anxiety disorders discussed include: Obsessive-compulsive and tic-related disorders, PTSD, and school refusal and panic disorder. Pharmacotherapy, CBT, and Parent-Child interaction therapies are reviewed.

This book presents an original approach to the study of psychiatry that is based on a justified epistemological position, which demands that both the natural and the human/social sciences are necessary in developing our understanding. Psychiatry as a medical specialism was constructed in the nineteenth century through the interplay of both the natural sciences and the human/social sciences. This interplay has created a hybrid discipline that spans biological and socio-cultural-historical domains, which has raised challenges for its understanding and research. This book focuses on one of the principal challenges - how can we explore mental symptoms and mental disorders as complexes of neurobiology on the one hand and meaning on the other? The chapters in this book, dedicated to German E Berrios, founder of the Cambridge school of psychopathology, tackles distinctive aspects of psychopathology or related areas. By means of a combination of approaches, chapters seek to unfold another element in our understanding of this field as well as raise new directions for its further study. Rethinking Psychopathology is a valuable resource for clinical psychologists and psychotherapists, psychological researchers, historians of psychology, cultural psychologists, critical psychologists, social scientists, philosophers of psychology, and philosophers of science.

Wherever people are working, there is some type of stress-and where there is stress, there is the risk of burnout. It is widespread, the subject of numerous studies in the U.S. and abroad. It is also costly, both to individuals in the form of sick days, lost wages, and emotional exhaustion, and to the workplace in terms of the bottom line. But as we are now beginning to understand, burnout is also preventable.

"Burnout for Experts" brings multifaceted analysis to a multilayered problem, offering comprehensive discussion of contributing factors, classic and less widely perceived markers of burnout, coping strategies, and treatment methods. International perspectives consider phase models of burnout and differentiate between burnout and related physical and mental health conditions. By focusing on specific job and life variables including workplace culture and gender aspects, contributors give professionals ample means for recognizing burnout as well as its warning signs. Chapters on prevention and intervention detail effective programs that can be implemented at the individual and organizational levels. Included in the coverage:

. History of burnout: a phenomenon.

. Personal and external factors contributing to burnout.

. Depression and burnout

. Assessment tools and methods.

. The role of communication in burnout prevention.

. Active coping and other intervention strategies.

Skillfully balancing scholarship and accessibility, "Burnout for Experts" is a go-to resourcefor health psychologists, social workers, psychiatrists, and organizational, industrial, and clinical psychologists.

Gap junctions between glial cells or neurons are ubiquitously expressed in the mammalian brain and play a role in brain development including cell differentiation, cell migration and survival, and tissue homeostasis, as well as in human diseases including hearing loss, neuropathies, epilepsy, brain trauma, and cardiovascular disease. This volume provides neuroscience researchers and students with a single source for information covering the physiological, behavioral and pathophysiological roles of gap junctions in the brain. In addition, the book also discusses human disease conditions associated with mutations in single gap junction connexion genes, making it applicable to clinicians doing translational research. Finally, it includes reviews of pharmacological studies with gap junction blockers and openers, summarizing information obtained from phenotyping gap junctions mouse mutants.

Serves as the most current and comprehensive reference available covering the physiological, behavioral and pathophysiological roles of gap junctions in the brain.

Chapters summarize knowledge of the basic physiology of gap junctions in the brain, as well as of human disease conditions associated with mutations in single gap junction connexin genes.

Includes reviews of pharmacological studies with gap junction blockers and openers, summarizing information obtained from phenotyping gap junctions mouse mutants.

Recent work on emotional regulation gives a powerful new lens through which to view the evolution across childhood and adolescence of the lived experience and clinical presentation of depression.? We have a richer picture of the depressed child, and the child at risk for depression, in interaction with family and wider world.? We know more about the development and the developmental psychopathology of coping strategies. These advances give provocative clues to the actual processes whereby well-established risk and protective factors might interact to produce, sustain or curtail a depressive syndrome.? This in turn opens the door to treatment and prevention approaches that are truly developmentally informed. This is the philosophy behind this completely updated and comprehensive analysis of childhood depression.

An examination of how female same-sex desires were represented in a wide range of Italian and British medical writings, 1870-1920. It shows how the psychiatric category of sexual inversion was positioned alongside other medical ideas of same-sex desires, such as the virago, tribade-prostitute, fiamma and gynaecological explanations.

Dr. Karl A. Menninger was one of the earliest supporters of psychoanalysis in America and, together with his father, Dr. C.F. Menninger, founded the internationally famous Menninger Clinic. Dr. Menninger is also a prolific letter writer who has carried on a lively correspondence with his fellow analysts and other notables all over the world. This selection of Dr. Menninger's correspondence begins in 1919, when he opened his first practice in Topeka, and covers the period in which he began the Menninger Clinic and published three major books. Dr. Menninger's growing prominence during these years was paralleled by the development of the American psychoanalytic community. The letters chart this development through Dr. Menninger's exchanges with such distinguished figures in American psychiatry as E.E. Southard, Adolf Meyer, Abraham Myerson, William Alanson White, Smith Ely Jelliffe, and Franz Alexander. Through his letters, Dr. Menninger is revealed as a keen observer of American society, a formidable combatant in psychiatric disputes, and a witty commentator on current events. His correspondence provides a vivid picture of the early years of American psychoanalysis and of a pivotal figure in this movement.

This volume assembles the leading aggression researchers both at the preclinical and clinical level. They review the current state of knowledge about neural mechanisms of aggressive behavior and point to the need for innovative methodologies to further our understanding of this greatly understudied set of behaviors.

Why do so many people suffer the slings and arrows of outrageous angst? Some twenty percent of us are afflicted with common Anxiety and Depressive disorders. That's not just nervous or scared or sad - that is painful dysfunction without obvious benefit. This angst comes from an evolutionary inheritance that biologically shaped us into social communities. There are just five specific diagnostic subtypes that account for most of this modern-day angst: Panic Anxiety, Social Anxiety, OCD, Atypical Depression and Melancholic Depression. Each of the five comes from primeval social instincts that told our ancestors how to improve survival of their community DNA. These instincts are also very much alive and unfettered in other species today. Their potential link to our human distress was anticipated by both Darwin and Freud. We humans have greater instinctive consciousness than other creatures. Rational thoughts let us defy biological social instructions. One result of this uniquely human skill is that over-ridden social instincts complain to us in the painful language of emotional disorders. A few of us even tackle this pain head-on, in ways that can advance our intellectual creativity, social performance, and productivity. Our human intellectual abilities owe as much to our unique social software as to our greater brain processing power. Civilization is built upon our ability to maintain social harmony with ethics and government, and to find solace in technology, religion and beer. This novel theoretical synthesis offers a new framework for understanding what our knowledge of psychiatric neuroscience, clinical research, diagnosis and treatment. The central theory is explained in everyday language. It is supported by clinical observation, straightforward accounts of complex science, animal research, and quotes from both ancient writings and modern humor and lyrics. This fascinating new synthesis is written for the general public, mental health professionals and academic researchers alike.

Schools can play an important role in addressing the unmet mental health needs of youth by potentially increasing access to care in a cost-effective manner. This venue provides unparalleled access to youth and exemplifies a single setting through which the majority of children can be reached.? This very timely issue provides a much-needed analysis of the types of situations in which schools can and must address the mental health needs of their students, and the methodology for doing so.? With an eye towards current technologies (articles cover telepsychiatry and web-based interventions), authors review school-based interventions for students suffering from post-traumatic stress-syndrome, generalized anxiety, social anxiety, depression, ADHD, psychoses, substance abuse, and other disorders.? Of special interest are the articles covering bullying (including internet bullying) and mobilizing a crisis team after student death.

This issue discusses the diagnosis and treatment of major depressive disorder (MDD) and other depressive disorders, with an emphasis on the psychosocial aspects of depression: how it affects societies, how it is affected by culture, and what the true meaning of recovery is for those suffering from MDD. The issue is divided into three section: Etiology, Diagnosis and Treatment.? Authors address the evidence where biology and subjectivity meet.? They discuss what is adaptive and what is pathologic and discuss population-based solutions that take into account the specificity of the individual.? Authors also take into account combination treatments of psychotherapy and pharmacotherapy and weigh the treatment choices against specific patient subtypes.

Underestimated, under-researched, and often poorly understood, the body-focused repetitive disorders nevertheless cause human suffering that is serious, persistent, and pervasive. These disorders can occur in both adults and children and manifest themselves as hair pulling (trichotillomania), pathologic skin picking, thumb sucking, and nail biting. Although these disorders are common, very few medical students and residents hear them addressed in lectures or know where to begin when confronted with a patient presenting with these behaviors. Trichotillomania, Skin Picking, and Other Body-Focused Repetitive Behaviors seeks to remedy this situation by synthesizing the latest research on body-focused repetitive disorders and presenting it in a systematic, easy-to-grasp manner.

Much has changed in the more than a decade since the last book on this topic was published. This new volume reflects the most current and substantive research into the etiology and symptoms of body-focused repetitive disorders and therapeutic options. Organized in logical fashion, it begins with a review of the clinical characteristics, moves on to diagnosis and evaluation, and concludes with a full review of treatment options. Special features include: - Extensive material to help clinicians and patients understand the underlying purpose of engaging in these behaviors, which include, reducing tension, regulating strong emotion, and alleviating boredom.- Separate chapters on adults and children, who may have a different presentation and a different set of treatment options. An additional chapter focuses on the role of the child patient's family in the diagnosis and treatment of the disorder.- Thorough coverage of the full range of treatments -- including psychotherapy, medication, and alternative treatments -- which provides the clinician with an evidence-based approach to treating patients.- Discussion of the psychobiology of hair pulling and skin picking, which allows the reader to understand and contextualize the disorder from a neurological perspective and offers clues that may assist in optimizing treatment.- A presentation style that is detailed enough for clinicians, yet accessible enough for a lay audience, including patients with the disorder and the families who seek to understand and support them.

Trichotillomania, Skin Picking, and Other Body-Focused Repetitive Behaviors fills a critical gap in the literature by addressing this common and frequently debilitating disorder in an utterly current, highly practical, and wholly compassionate manner.

This completely new and updated issue takes a focused look at addiction psychiatry in three sections: Diagnostics, Therapeutics, and New Directions. Dr. Danovitch, from Cedars-Sinai and Dr. Mariani from Columbia hone in on the most rapidly advancing and relevant areas of addiction for practitioners today, from defining addiction (implications of DSM-V), to genetics and neurobiology, to specific treatment options for a variety of patient populations: for pregnant women, adolescents, and patients suffering from chronic pain, for example.? A variety of addiction types are discussed (ie, opioid, stimulant, and cannabis).? The issue closes with discussions of emerging trends, systems of care, investigational therapeutics and the role of the criminal justice system.

Psychodermatology is a relatively new field in evolution and thus, there is a comparative paucity of information in general. However, when it comes to children and adolescents there is a complete vacuum of information as no other book has aimed to specifically address the psychodermatological issues facing this particular population. For assessment, diagnosis, comprehensive treatment of children with psychodermatologic conditions and establishing a relationship between skin and psyche, there is a lack of clear and relevant clinical information about these complex disorders. The complexity of these disorders is related to lack of understanding in genetic, embryonic, physiologic, neuroimmunologic, neurocutaneous, stress-related neuromodulation, and psychosomatic interconnections. This book presents a clinically relevant approach to the management of psychodermatologic issues encountered in normal practice. Various classifications and major categories that are discussed include psychophysiologic disorders, psychiatric conditions with dermatologic manifestations, dermatologic disorders predisposing to psychiatric disorders, systemic diseases with psychodermatological manifestations, and special issues in management of psychocutaneous disorders in children and adolescents.

Desire and the Female Therapist is one of the first full-length explorations of erotic transference and countertransference from the point of view of the female therapist. Particular attention is given to the female therapist/male client relationship and to the effects of desire made visible in art objects in analytical forms of psychotherapy. Drawing on aesthetic and psychoanalytic theory, specifically Lacan and Jung, the book offers a significant new approach to desire in therapy. Richly illustrated, with pictures as well as clinical vignettes, this book follows on from Joy Schaverien's innovative previous work The Revealing Image. Written primarily for psychotherapists, art therapists and analysts, Desire and the Female Therapist will be essential reading for all therapists affected by erotic transference and countertransference in the course of clinical practice and all whose clients bring art works to therapy.

'Wise, timely and eloquent... A joy to read.' Guardian What does it mean to be well? Is it something in our body? Or, is it rather something subjective - something of the mind? In this profound collection of clinical stories, eminent psychiatrist Dr Alastair Santhouse draws on his experience of treating thousands of hospital patients to show how our emotions are inextricably linked to our physical wellbeing. Our minds shape the way we understand and react to symptoms that we develop, dictate the treatments we receive, and influence whether they work. They even influence whether we develop symptoms at all. Written with brutal honesty, deep compassion, and a wry sense of humour, Head First examines difficult cases that illuminate some of our most puzzling and controversial medical issues-from the tragedy of suicide, to the stigma surrounding obesity, to the ongoing misery of chronic fatigue. Ultimately he finds that our medical model has failed us by promoting specialization and overlooking perhaps the single most important component of our health: our state of mind.

The goal of this issue is to provide readers with a basic understanding of common chronic illnesses that begin in childhood (even at the time of conception), an understanding of the role of the family and mental health issues and how they may affect treatment adherence, and challenges faced when transitioning to adulthood. A special article is dedicated to the pediatric medical home. Several articles address the psychiatric challenges of very premature infants, behavioral and psychiatric concerns for genetically neurodevelopmentally challenged children, and the developmental perspective of children and families with cystic fibrosis. Other articles are devoted to potentially lifelong chronic illnesses, including inflammatory bowel disease, asthma, diabetes mellitus, obesity, and epilepsy. The issue ends with articles devoted to potential life-threatening illnesses, including HIV and oncologic illnesses, and finishes with an article on palliative care

This book focuses on the role of the psychiatric, medical and nutritional assessment and management of severely ill patients with anorexia and bulimia nervosa. Lead clinicians and researchers address the essentials of risk assessment, the identification of complications and the monitoring of treatment progress. Location of care and the role of the team are fully addressed, with due consideration of legal and ethical issues. Practical guidelines are included on risk assessment, management of acute and chronic physical problems, feeding during treatment and consent, as outlined in the MARSIPAN (2010) and Junior MARSIPAN (2012)documents. Assessment and Management of Medical Problems in Eating Disorders will be of value for GPs, psychiatrists, medical teams and all health-care professionals involved in the treatment and management of anorexia and bulimia nervosa and related eating disorders. "