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Active Pharmaceutical Ingredients in Synthesis - Catalytic Processes in Research and Development (Hardcover)
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Active Pharmaceutical Ingredients in Synthesis - Catalytic Processes in Research and Development (Hardcover)
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Presents the most effective catalytic reactions in use today, with
a special focus on process intensification, sustainability, waste
reduction, and innovative methods This book demonstrates the
importance of efficient catalytic transformations for producing
pharmaceutically active molecules. It presents the key catalytic
reactions and the most efficient catalytic processes, including
their significant advantages over compared previous methods. It
also places a strong emphasis on asymmetric catalytic reactions,
process intensification (PI), sustainability and waste mitigation,
continuous manufacturing processes as enshrined by continuous flow
catalysis, and supported catalysis. Active Pharmaceutical
Ingredients in Synthesis: Catalytic Processes in Research and
Development offers chapters covering: Catalysis and Prerequisites
for the Modern Pharmaceutial Industry Landscape; Catalytic Process
Design - The Industrial Perspective; Hydrogenation,
Hydroformylation and Other Reductions; Oxidation;; Catalytic
Addition Reactions; Catalytic Cross-Coupling Reactions; Catalytic
Metathesis Reactions; Catalytic Cycloaddition Reactions: Coming
Full-Circle; Catalytic Cyclopropanation Reactions; Catalytic C-H
insertion Reactions; Phase Transfer Catalysis; and Biocatalysis.
-Provides the reader with an updated clear view of the current
state of the challenging field of catalysis for API production
-Focuses on the application of catalytic methods for the synthesis
of known APIs -Presents every key reaction, including Diels-Alder,
CH Insertions, Metal-catalytic coupling-reactions, and many more
-Includes recent patent literature for completeness Covering a
topic of great interest for synthetic chemists and R&D
researchers in the pharmaceutical industry, Active Pharmaceutical
Ingredients in Synthesis: Catalytic Processes in Research and
Development is a must-read for every synthetic chemist working with
APIs.
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