Your cart is empty
This book explains task management concepts and outlines practical knowledge to help pharmaceutical analytical scientists become productive and enhance their career. -Presents broad topics such as product development process, regulatory requirement, task and project management, innovation mindset, molecular recognition, separation science, degradation chemistry, and statistics. -Provokes thinking through figures, tables, and case studies to help understand how the various functions integrate and how analytical development can work efficiently and effectively by applying science and creativity in their work. -Discusses how to efficiently develop a fit-for-purpose HPLC method without screening dozens of columns, gradients, or mobile phase combinations each time, since the extra effort may not provide enough of a benefit to justify the cost and time in a fast-paced product development environment. This book explains task management concepts and outlines practical knowledge to help pharmaceutical analytical scientists become productive and enhance their career. -Presents broad topics such as product development process, regulatory requirement, task and project management, innovation mindset, molecular recognition, separation science, degradation chemistry, and statistics. -Provokes thinking through figures, tables, and case studies to help understand how the various functions integrate and how analytical development can work efficiently and effectively by applying science and creativity in their work. -Discusses how to efficiently develop a fit-for-purpose HPLC method without screening dozens of columns, gradients, or mobile phase combinations each time, since the extra effort may not provide enough of a benefit to justify the cost and time in a fast-paced product development environment.
Elementary Principles of Chemical Processes, 4th Edition Student International Version prepares students to formulate and solve material and energy balances in chemical process systems and lays the foundation for subsequent courses in chemical engineering. The text provides a realistic, informative, and positive introduction to the practice of chemical engineering.
Fundamentals of Momentum, Heat, and Mass Transfer, now in its sixth edition, continues to provide a unified treatment of momentum transfer (fluid mechanics), heat transfer, and mass transfer. This new edition has been updated to include more coverage of modern topics and new applications, such as macro- and micro-scale chemical reactors. Additionally, the sixth edition focuses on an explicit problem-solving methodology that is thoroughly and consistently implemented throughout the text. It is designed for undergraduates taking transport phenomena or transfer and rate process courses.
One book dealing with the fundamentals of thermal and membrane desalination systems and discussing their economical as well as environmental aspects. With a growing population, climate change and greater water demand, desalination has increasingly become a part of the solution to regional water scarcity - seawater desalination capacity has roughly doubled in the past ten years. Desalination has also begun to receive more attention in academia, with research focusing on improving energy efficiency and system robustness and lowering capital costs. With this book, an introduction is given to the basics and fundamentals of desalination systems. Both, thermal and membrane desalination systems, are covered and discussed in view of energy, exergy, economic and environmental aspects. In the beginning, Introduction to Desalination: Systems, Processes and Environmental Impacts describes multi effect evaporation, vapor compression and multi-stage flashing. Further chapters deal with common membrane-based separations like reverse osmosis and membrane filtration, forward osmosis, diffusion dialysis and pervaporation as well as thermo-osmosis, electrodialysis and electrodeionization. Subsequently, hybrid systems are discussed, and the economic analysis of such systems and their environmental impact are highlighted. Each chapter contains theoretical and practical examples and concludes with questions and problems for self-study. * Needed: Desalination has become a part of the solution to regional water scarcity and an introductory book in this field is urgently needed. * Balanced Approach: Presents the fundamentals of thermal and membrane desalination systems. * Learning Material: Each chapter includes exercises for self-study and Instructors can find teaching material online. Introduction to Desalination: Systems, Processes and Environmental Impacts is an important resource for master's students in engineering sciences, lecturers in chemical and mechanical engineering, engineers, environmental chemists, as well as process engineers, engineering scientists in industry, and environmental consultants.
This third edition provides chemical engineers with process control techniques that are used in practice while offering detailed mathematical analysis. Numerous examples and simulations are used to illustrate key theoretical concepts. New exercises are integrated throughout several chapters to reinforce concepts. Up-to-date information is also included on real-time optimization and model predictive control to highlight the significant impact these techniques have on industrial practice. And chemical engineers will find two new chapters on biosystems control to gain the latest perspective in the field.
This is an introduction to the dynamics of fluids at small scales, the physical and mathematical underpinnings of Brownian motion, and the application of these subjects to the dynamics and flow of complex fluids such as colloidal suspensions and polymer solutions. It brings together continuum mechanics, statistical mechanics, polymer and colloid science, and various branches of applied mathematics, in a self-contained and integrated treatment that provides a foundation for understanding complex fluids, with a strong emphasis on fluid dynamics. Students and researchers will find that this book is extensively cross-referenced to illustrate connections between different aspects of the field. Its focus on fundamental principles and theoretical approaches provides the necessary groundwork for research in the dynamics of flowing complex fluids.
Statistical Thermodynamics: An Engineering Approach covers in a practical, readily understandable manner the underlying meaning of entropy, temperature and other thermodynamic concepts, the foundations of quantum mechanics, and the physical basis of gas, liquid and solid phase properties. It presents simply the relationship between macroscopic and microscopic thermodynamics. In addition, the molecular basis of transport phenomena and chemical kinetics are explored, as are basic concepts in spectroscopy. Modern computational tools for solving thermodynamic problems are explored, and the student is assured that he or she will gain knowledge of practical usefulness. This essential text is suitable for mechanical or aerospace engineering graduate students who have a strong background in engineering thermodynamics, those entering advanced fields such as combustion, high temperature gas dynamics, environmental sciences, or materials processing, and those who wish to build a background for understanding advanced experimental diagnostic techniques in these or similar fields.
Written by a highly regarded author with industrial and academic experience, this new edition of an established bestselling book provides practical guidance for students, researchers, and those in chemical engineering. The book includes a new section on sustainable energy, with sections on carbon capture and sequestration, as a result of increasing environmental awareness; and a companion website that includes problems, worked solutions, and Excel spreadsheets to enable students to carry out complex calculations.
With this unique and comprehensive text, readers will gain the quantitative tools needed to engineer the particulate processes and products that are ubiquitous in modern life. Covering a series of particle and particulate delivery form design processes, with emphasis on design and operation to control particle attributes, and supported by many worked examples, it is essential reading for students and practitioners. Topics covered include a range of particle design processes such as crystallization and precipitation, granulation, grinding, aerosol processes and spray drying, as well as forms of delivery such as granules, tablets, dry powders, and aerosols. Readers will learn from real-world examples how the primary particle properties and the structure and properties of the delivery form can lead to high performance products, ranging from pharmaceuticals, consumer goods and foods, to specialty chemicals, paints, agricultural chemicals and minerals.
This indispensable guide will equip the reader with a thorough understanding of the field of foaming chemistry. Assuming only basic theoretical background knowledge, the book provides a straightforward introduction to the principles and properties of foams and foaming surfactants. It discusses the key ideas that underpin why foaming occurs, how it can be avoided and how different degrees of antifoaming can be achieved, and covers the latest test methods, including laboratory and industrial developed techniques. Detailing a variety of different kinds of foams, from wet detergents and food foams, to polymeric, material and metal foams, it connects theory to real-world applications and recent developments in foam research. Combining academic and industrial viewpoints, this book is the definitive stand-alone resource for researchers, students and industrialists working on foam technology, colloidal systems in the field of chemical engineering, fluid mechanics, physical chemistry, and applied physics.
A comprehensive source of information about modern drying technologies that uniquely focus on the processing of pharmaceuticals and biologicals Drying technologies are an indispensable production step in the pharmaceutical industry and the knowledge of drying technologies and applications is absolutely essential for current drug product development. This book focuses on the application of various drying technologies to the processing of pharmaceuticals and biologicals. It offers a complete overview of innovative as well as standard drying technologies, and addresses the issues of why drying is required and what the critical considerations are for implementing this process operation during drug product development. Drying Technologies for Biotechnology and Pharmaceutical Applications discusses the state-of-the-art of established drying technologies like freeze- and spray- drying and highlights limitations that need to be overcome to achieve the future state of pharmaceutical manufacturing. The book also describes promising next generation drying technologies, which are currently used in fields outside of pharmaceuticals, and how they can be implemented and adapted for future use in the pharmaceutical industry. In addition, it deals with the generation of synergistic effects (e.g. by applying process analytical technology) and provides an outlook toward future developments. -Presents a full technical overview of well established standard drying methods alongside various other drying technologies, possible improvements, limitations, synergies, and future directions -Outlines different drying technologies from an application-oriented point of view and with consideration of real world challenges in the field of drug product development -Edited by renowned experts from the pharmaceutical industry and assembled by leading experts from industry and academia Drying Technologies for Biotechnology and Pharmaceutical Applications is an important book for pharma engineers, process engineers, chemical engineers, and others who work in related industries.
A systematic approach to profit optimization utilizing strategic solutions and methodologies for the chemical process industry In the ongoing battle to reduce the cost of production and increase profit margin within the chemical process industry, leaders are searching for new ways to deploy profit optimization strategies. Profit Maximization Techniques For Operating Chemical Plants defines strategic planning and implementation techniques for managers, senior executives, and technical service consultants to help increase profit margins. The book provides in-depth insight and practical tools to help readers find new and unique opportunities to implement profit optimization strategies. From identifying where the large profit improvement projects are to increasing plant capacity and pushing plant operations towards multiple constraints while maintaining continuous improvements--there is a plethora of information to help keep plant operations on budget. The book also includes information on: Take away methods and techniques for identifying and exploiting potential areas to improve profit within the plant Focus on latest Artificial Intelligence based modeling, knowledge discovery and optimization strategies to maximize profit in running plant. Describes procedure to develop advance process monitoring and fault diagnosis in running plant Thoughts on engineering design, best practices and monitoring to sustain profit improvements Step-by-step guides to identifying, building, and deploying improvement applications For leaders and technologists in the industry who want to maximize profit margins, this text provides basic concepts, guidelines, and step-by-step guides specifically for the chemical plant sector.
Uniquely focusing on dynamic modeling, this volume incorporates metabolic regulation as a survival mechanism for cells, by driving metabolism through optimal investment of its resources for control of enzyme synthesis and activity. Consequently, the models have a proven record of describing various uptake patterns of mixed carbon substrates that have become significant in modern applications of biomass for the production of bioenergy. The models accurately describe dynamic behavior of microbes in nutrient environments with mixtures of complementary substrates, such as carbon and nitrogen. Modeling of large metabolic networks (including prospects for extension to genome scale) is enabled by lumped hybrid cybernetic models with an unparalleled capacity to predict dynamic behavior of knockout strains. This is an invaluable, must-have reference for bio-researchers and practicing engineers.
Master the finite element method with this masterful and practical volume An Introduction to the Finite Element Method (FEM) for Differential Equations provides readers with a practical and approachable examination of the use of the finite element method in mathematics. Author Mohammad Asadzadeh covers basic FEM theory, both in one-dimensional and higher dimensional cases. The book is filled with concrete strategies and useful methods to simplify its complex mathematical contents. Practically written and carefully detailed, An Introduction to the Finite Element Method covers topics including: An introduction to basic ordinary and partial differential equations The concept of fundamental solutions using Green's function approaches Polynomial approximations and interpolations, quadrature rules, and iterative numerical methods to solve linear systems of equations Higher-dimensional interpolation procedures Stability and convergence analysis of FEM for differential equations This book is ideal for upper-level undergraduate and graduate students in natural science and engineering. It belongs on the shelf of anyone seeking to improve their understanding of differential equations.
This is the first comprehensive guide to the principles and techniques of chemical looping partial oxidation. With authoritative explanations from a pioneer of the chemical looping process, you will: * Gain a holistic overview of metal oxide reaction engineering, with coverage of ionic diffusion, nanostructure formation, morphological evolution, phase equilibrium, and recyclability properties of metal oxides during redox reactions * Learn about the gasification of solid fuels, the reforming of natural gas, and the catalytic conversion of methane to olefins * Understand the importance of reactor design and process integration in enabling metal oxide oxygen carriers to produce desired products * Discover other applications of catalytic metal oxides, including the production of maleic anhydride and solar energy conversions Aspen Plus (R) simulation software and results accompany the book online. This is an invaluable reference for researchers and industry professionals in the fields of chemical, energy and environmental engineering, and students studying process design and optimization.
Metaheuristics exhibit desirable properties like simplicity, easy parallelizability and ready applicability to different types of optimization problems such as real parameter optimization, combinatorial optimization and mixed integer optimization. They are thus beginning to play a key role in different industrially important process engineering applications, among them the synthesis of heat and mass exchange equipment, synthesis of distillation columns and static and dynamic optimization of chemical and bioreactors.
This book explains cutting-edge research techniques in related computational intelligence domains and their applications in real-world process engineering. It will be of interest to industrial practitioners and research academics.
The Study Guide is designed as a teaching aid to be used in conjunction with the book Alive and Well at the End of the Day: The Supervisor's Guide to Managing Safety in Operations, written by Paul D. Balmert. The book is designed to teach front-line supervisors of workers in a wide range of industries how to help and guide their employees to understand the risks involved in the various aspects of their work, and how to cope with those risks and to plan and execute their jobs in ways that can help eliminate accidents. Created by the highly experienced training specialists of Balmert Consulting, the Study Guide utilizes training best practices to help affix the principals of Alive and Well at the End of the Day: The Supervisor's Guide to Managing Safety in Operations in the minds of the reader. The use of strategically-crafted questions both at the beginning and end of each review session allows the reader to work with the material and become more familiar with it. The book was developed in response to multiple requests from readers of Alive and Well at the End of the Day: The Supervisor's Guide to Managing Safety in Operations who enthusiastic about the messages and ideas in the book wanted to find ways to make it become part of their operation s safety culture and practices. For more information on Alive and Well at the End of the Day: The Supervisor's Guide to Managing Safety in Operations visit: http://www.wiley.com/WileyCDA/WileyTitle/productCd-047046707X.html
The only textbook that applies thermodynamics to real-world process engineering problems This must-read for advanced students and professionals alike is the first book to demonstrate how chemical thermodynamics work in the real world by applying them to actual engineering examples. It also discusses the advantages and disadvantages of the particular models and procedures, and explains the most important models that are applied in process industry. All the topics are illustrated with examples that are closely related to practical process simulation problems. At the end of each chapter, additional calculation examples are given to enable readers to extend their comprehension. Chemical Thermodynamics for Process Simulation instructs on the behavior of fluids for pure fluids, describing the main types of equations of state and their abilities. It discusses the various quantities of interest in process simulation, their correlation, and prediction in detail. Chapters look at the important terms for the description of the thermodynamics of mixtures; the most important models and routes for phase equilibrium calculation; models which are applicable to a wide variety of non-electrolyte systems; membrane processes; polymer thermodynamics; enthalpy of reaction; chemical equilibria, and more. -Explains thermodynamic fundamentals used in process simulation with solved examples -Includes new chapters about modern measurement techniques, retrograde condensation, and simultaneous description of chemical equilibrium -Comprises numerous solved examples, which simplify the understanding of the often complex calculation procedures, and discusses advantages and disadvantages of models and procedures -Includes estimation methods for thermophysical properties and phase equilibria thermodynamics of alternative separation processes -Supplemented with MathCAD-sheets and DDBST programs for readers to reproduce the examples Chemical Thermodynamics for Process Simulation is an ideal resource for those working in the fields of process development, process synthesis, or process optimization, and an excellent book for students in the engineering sciences.
Written in a clear, logical and concise manner, this comprehensive resource provides discussion on essential mathematical tools, required for upgraded system performance. Understanding of basic principles and governing laws is essential to reduce complexity of the system, and this guide offers detailed discussion on analytical and numerical techniques to solve mathematical model equations. Important concepts including nonlinear algebraic equations, initial value ordinary differential equations (ODEs) and boundary value ODEs are discussed in detail. The concepts of optimization methods and sensitivity analysis, which are important from subject point of view, are explained with suitable examples. Numerous problems and MATLAB (R)/Scilab exercises are interspersed throughout the text. Several case studies involving full details of simulation are offered for better understanding. The accompanying website will host additional MATLAB (R)/Scilab problems, model question papers, simulation exercises, tutorials and projects. This book will be useful for students of chemical engineering, mechanical engineering, instrumentation engineering and mathematics.
An all-in-one practical guide on how to efficiently use chromatographic separation methods Based on a training course that teaches the theoretical as well as practical aspects of protein bioseparation to bioprocess professionals, this fully updated and revised new edition offers comprehensive coverage of continuous chromatography and provides readers with many relevant examples from the biopharmaceutical industry. Divided into two large parts, Protein Chromatography: Process Development and Scale-Up, Second Edition presents all the necessary knowledge for effective process development in chromatographic bioseparation, both on small and large scale. The first part introduces chromatographic theory, including process design principles, to enable the reader to rationalize the set-up of a bioseparation process. The second part illustrates by way of case studies and sample protocols how the theory learned in the first part may be applied to real-life problems. Chapters look at: Downstream Processing of Biotechnology Products; Chromatography Media; Laboratory and Process Columns and Equipment; Adsorption Equilibrium; Rate Processes; and Dynamics of Chromatography Columns. The book closes with chapters on: Effects of Dispersion and Rate Processes on Column Performance; Gradient Elution Chromatography; and Chromatographic Column Design and Optimization. -Presents the most pertinent examples from the biopharmaceutical industry, including monoclonal antibodies -Provides an overview of the field along with design tools and examples illustrating the advantages of continuous processing in biopharmaceutical productions -Focuses on process development and large-scale bioseparation tasks, making it an ideal guide for the professional bioengineer in the biotech and pharma industries -Offers field-tested information based on decades of training courses for biotech and chemical engineers in Europe and the U.S. Protein Chromatography: Process Development and Scale-Up, Second Edition will appeal to biotechnologists, analytical chemists, chromatographers, chemical engineers, pharmaceutical industry, biotechnological industry, and biochemists.
A guide to the fundamentals of applied gas chromatography and the process gas chromatograph, with practical procedures for design and troubleshooting This comprehensive resource provides the theory that underpins a full understanding of the fundamental techniques of gas chromatography and the process analyzer. Without relying on complex mathematics, the book addresses hands-on applications of gas chromatographs within process industries. The author - a noted expert on the topic - details both the scientific information needed to grasp the material presented and the practical applications for professionals working in the field. Process Gas Chromatographs: Fundamentals, Design and Implementation comprises 15 chapters, a glossary of terms and a series of self-assessment questions and quizzes. This important resource: Describes practical procedures for design and troubleshooting Contains concise chapters that provide a structured course for advanced students in process engineering Reviews the fundamentals of applied gas chromatography Details the operation and maintenance of process gas chromatographs Offers a summary, and self-assessment questions, for every chapter Is written by an international expert in the field with extensive industry knowledge and teaching experience in courses on process sampling systems and gas chromatography Written for process analyzer engineers and technicians, application engineers, and industrial environmental engineers, Process Gas Chromatographs: Fundamentals, Design and Implementation offers an essential guide to the basics of gas chromatography and reviews the applications of process gas chromatographs in industry today.
Fully revised to match the more traditional sequence of course materials, this full-color second edition presents the basic principles and methods of thermodynamics using a clear and engaging style and a wealth of end-of-chapter problems. It includes five new chapters on topics such as mixtures, psychrometry, chemical equilibrium, and combustion, and discussion of the Second Law of Thermodynamics has been expanded and divided into two chapters, allowing instructors to introduce the topic using either the cycle analysis in Chapter 6 or the definition of entropy in Chapter 7. Online ancillaries including a password-protected solutions manual, figures in electronic format, prepared PowerPoint lecture slides, and instructional videos are available.
This textbook presents key theoretical approaches to understanding issues of sustainability and environmental management, perfectly bridging the gap between engineering and environmental science. It begins with the fundamentals of environmental modelling and toxicology, which are then used to discuss qualitative and quantitative risk assessment methods, and environmental assessments of product design. It discusses how business and government can work towards sustainability, focusing on managerial and legal tools, before considering ethics and how decisions on environmental management can be made. Students will learn quantitative methods while also gaining an understanding of qualitative, legal, and ethical aspects of sustainability. Practical applications are included throughout, and there are study questions at the end of each chapter. PowerPoint slides and jpegs of all the figures in the book are provided online. This is the perfect textbook on environmental studies for engineering and applied science students.
The proposed book focusses on metal mediated/catalyzed "controlled/living radical polymerization" (CRP/LRP) methods. It surveys a wide variety of catalyzed polymerization reactions, making it essentially a "one stop" review in the field. A significant contribution to polymer science is "metathesis polymerization" discovered by Grubbs and others. The book will cover various metathesis polymerization methods and implications in polymer industry.
A guide to the technical and calculation problems of chemical reactor analysis, scale-up, catalytic and biochemical reactor design Chemical Reactor Design offers a guide to the myriad aspects of reactor design including the use of numerical methods for solving engineering problems. The author - a noted expert on the topic - explores the use of transfer functions to study residence time distributions, convolution and deconvolution curves for reactor characterization, forced-unsteady-state-operation, scale-up of chemical reactors, industrial catalysis, design of multiphasic reactors, biochemical reactors design, as well as the design of multiphase gas-liquid-solid reactors. Chemical Reactor Design contains several examples of calculations and it gives special emphasis on the numerical solutions of differential equations by using the finite differences approximation, which offers the background information for understanding other more complex methods. The book is designed for the chemical engineering academic community and includes case studies on mathematical modeling by using of MatLab software. This important book: - Offers an up-to-date insight into the most important developments in the field of chemical, catalytic, and biochemical reactor engineering - Contains new aspects such as the use of numerical methods for solving engineering problems, transfer functions to study residence time distributions, and more - Includes illustrative case studies on MatLab approach, with emphasis on numerical solution of differential equations using the finite differences approximation Written for chemical engineers, mechanical engineers, chemists in industry, complex chemists, bioengineers, and process engineers, Chemical Reactor Design addresses the technical and calculation problems of chemical reactor analysis, scale-up, as well as catalytic and biochemical reactor design.
You may like...
Chemical Engineering Design - SI Edition
Ray Sinnott, Gavin Towler Paperback
Chemical Engineering Primer with…
Hussein K. Abdel-Aal Paperback R1,697 Discovery Miles 16 970
Optimization in Chemical Engineering
Suman Dutta Hardcover R1,553 Discovery Miles 15 530
Energetic Materials and Munitions - Life…
Adam Stewart Cumming, Mark S. Johnson Hardcover
Introduction to Chemical Engineering…
William M. Deen Hardcover R1,678 Discovery Miles 16 780
Emerging Areas in Bioengineering
Ho Nam Chang Hardcover
Conservation Equations And Modeling Of…
Said S.E.H. Elnashaie, Parag Garhyan Hardcover R5,494 Discovery Miles 54 940
Corporate Financial Distress…
Edward I. Altman, Edith Hotchkiss, … Hardcover
Modern Trends in Chemistry and Chemical…
A.K. Haghi Hardcover R2,532 Discovery Miles 25 320
Statistics for Process Control Engineers…
Myke King Hardcover