This thesis demonstrates a technology that enables pipetting-free high-throughput screening (HTS) on a miniaturized platform, eliminating the need for thousands of one-by-one pipetting and conventional liquid handling systems. This platform enhances accessibility to HTS and enables HTS to be used in small-to-medium scale laboratories. In addition, it allows large-scale combinatorial screening with a small number of valuable cells, such as patients' primary cancer cells. This technique will have a high impact for widespread use of HTS in the era of personalized medicine. In this thesis, the author firstly describes the need and concept of 'partipetting' for pipetting-free HTS platform. It is realized by the one-step pipetting and self-assembly of encoded drug-laden microparticles (DLPs) on the microwells. Next, the technical implementations required for the platform demonstration are described. It includes preparation of encoded DLPs, plastic chip fabrication, and realization of automated system. Lastly, screening of sequential drug combinations using this platform is demonstrated. This shows the potential of the proposed technology for various applications.

Research on nanotechnology has mainly focused on the aspects of synthesis of nanomaterials that have unique chemical, thermal, and mechanical properties applicable to a wide range of applications. A variety of properties and phenomena have been investigated, and many of the studies have been directed toward understanding the properties and applications of nanomaterials. Nanomaterials have properties that are useful for enhancing surface-to-volume ratio, reactivity, strength, and durability. Due to their enhanced chemical and mechanical properties, the nanomaterials play promising roles in enhancing the desulfurization. Nanocomposites for the Desulfurization of Fuels is an essential reference source that discusses the synthesis, properties, and technological developments of nanomaterials and their applications in petroleum. Featuring research on topics such as hybrid materials, catalytic properties, and environmental concerns, this book is ideally designed for chemical engineers, scientists, researchers, academicians, and students in fields that include chemistry, petroleum, materials science, physics, and engineering.

New edition of the popular textbook, comprehensively updated throughout and now includes a new dedicated website for gas dynamic calculations The thoroughly revised and updated third edition of Fundamentals of Gas Dynamics maintains the focus on gas flows below hypersonic. This targeted approach provides a cohesive and rigorous examination of most practical engineering problems in this gas dynamics flow regime. The conventional one-dimensional flow approach together with the role of temperature-entropy diagrams are highlighted throughout. The authors--noted experts in the field--include a modern computational aid, illustrative charts and tables, and myriad examples of varying degrees of difficulty to aid in the understanding of the material presented. The updated edition of Fundamentals of Gas Dynamics includes new sections on the shock tube, the aerospike nozzle, and the gas dynamic laser. The book contains all equations, tables, and charts necessary to work the problems and exercises in each chapter. This book's accessible but rigorous style: Offers a comprehensively updated edition that includes new problems and examples Covers fundamentals of gas flows targeting those below hypersonic Presents the one-dimensional flow approach and highlights the role of temperature-entropy diagrams Contains new sections that examine the shock tube, the aerospike nozzle, the gas dynamic laser, and an expanded coverage of rocket propulsion Explores applications of gas dynamics to aircraft and rocket engines Includes behavioral objectives, summaries, and check tests to aid with learning Written for students in mechanical and aerospace engineering and professionals and researchers in the field, the third edition of Fundamentals of Gas Dynamics has been updated to include recent developments in the field and retains all its learning aids. The calculator for gas dynamics calculations is available at https: //www.oscarbiblarz.com/gascalculator gas dynamics calculations

Production, new materials development, and mechanics are the central subjects of modern industry and advanced science. With a very broad reach across several different disciplines, selecting the most forward-thinking research to review can be a hefty task, especially for study in niche applications that receive little coverage. For those subjects, collecting the research available is of utmost importance. The Handbook of Research on Advancements in Manufacturing, Materials, and Mechanical Engineering is an essential reference source that examines emerging obstacles in these fields of engineering and the methods and tools used to find solutions. Featuring coverage of a broad range of topics including fabricating procedures, automated control, and material selection, this book is ideally designed for academics; tribology and materials researchers; mechanical, physics, and materials engineers; professionals in related industries; scientists; and students.

"Perovskite-Based Solar Cells: From Fundamentals to Tandem Devices" gives fundamental understanding of perovskite solar cells from the chemical composition of each thin layer composing the different stacks to the whole device. Special attention has been given to the development of the materials forming the perovskite solar cell and their effect on the device performance, in addition to the recent progress of this emerging technology. Moreover, light has been shed on the perovskite elaboration techniques, in addition to the several techniques proposed to improve both the efficiency and the stability of perovskite solar cells. Furthermore, special emphasis was given to the three types of tandem solar cells and their recent advances starting from Perovskite/perovskite tandem solar cells to Perovskite/ CIGS tandem cells to perovskite/ heterojunction silicon tandem solar cells. The latter constitute a promising solution to improve photovoltaic solar cells performance.

Although first described by Winsor in 1954, the chemistry and technology of microemulsions attracts considerable research interest. Until relatively recently, microemulsions were not used in large scale applications as their phase behaviour and microstructure were not well understood and large amounts of surfactant were needed for their formulation. With increased understanding of their behaviour and significantly improved methods for formulating and tuning their properties, microemulsions are becoming increasingly useful in a range of industrial and research applications.
Covering both the advances that have enabled improved understanding of microemulsions, and the applications in a range of industrial and research settings, and written by a first class team of contributors, this book will be essential reading for anyone using, or considering using microemulsions in the course of their work. Written for research chemists, technologists and engineers in the fine, specialty chemicals and polymer industries, and those in university or government laboratories, this book will be particularly valuable to those early on in their careers.

This book describes rubber nanocomposites and their applications in the automobile sector. Newly developed nanofibres and nanofinished textiles, with their novel characteristics and various applications in next-generation automobiles, are also discussed. Lastly, a comprehensive evaluation and overview of the impact of nanotechnology on the textiles in automobile industries are presented.

Advances in Biomembranes and Lipid Self-Assembly, Volume 28, formerly titled Advances in Planar Lipid Bilayers and Liposomes, provides a global platform for the study of cell membranes, lipid model membranes, and lipid self-assemblies, from the micro- to the nanoscale. Planar lipid bilayers are widely studied due to their ubiquity in nature. This book presents research on their application in the formulation of biomimetic model membranes, and in the design of artificial dispersion of liposomes. Moreover, the book discusses how lipids self-assemble into a wide range of other structures, including micelles and the liquid crystalline hexagonal and cubic phases. Chapters in this volume present both original research and comprehensive reviews written by world leading experts and young researchers.

Safety of Lithium Batteries describes how best to assure safety during all phases of the life of Lithium ion batteries (production, transport, use, and disposal). About 5 billion Li-ion cells are produced each year, predominantly for use in consumer electronics. This book describes how the high-energy density and outstanding performance of Li-ion batteries will result in a large increase in the production of Li-ion cells for electric drive train vehicle (xEV) and battery energy storage (BES or EES) purposes. The high-energy density of Li battery systems comes with special hazards related to the materials employed in these systems. The manufacturers of cells and batteries have strongly reduced the hazard probability by a number of measures. However, absolute safety of the Li system is not given as multiple incidents in consumer electronics have shown.

Advances in Organometallic Chemistry, Volume 69, contains authoritative review articles of world renowned researchers in the field of organometallic chemistry. This longstanding serial is known for its comprehensive coverage of topics in organometallic synthesis, reactions, mechanisms, homogeneous catalysis, and more, with this release focusing on topics such as C-H Activation Mediated by Main Group Inorganic and Organometallic Compounds, Transition-metals catalyzed intramolecular amination and hydroamination reactions of allenes, Green Fluorescent Protein-like and related organometallic fluorophores, Recent advances in the synthesis of C- S- bonds via metal-catalyzed functionalization of C- H- bonds, Current mechanistic understanding of Co-catalyzed C-H functionalization, and more. The book is ideal for a wide range of researchers involved in organometallic chemistry, including synthetic protocols, mechanistic studies and practical applications.

In today's global context, there has been extensive research conducted in reducing harmful emissions to conserve and protect our environment. In the automobile and power generation industries, diesel engines are being utilized due to their high level of performance and fuel economy. However, these engines are producing harmful pollutants that contribute to several global threats including greenhouse gases and ozone layer depletion. Professionals have begun developing techniques to improve the performance and reduce emissions of diesel engines, but significant research is lacking in this area. Recent Technologies for Enhancing Performance and Reducing Emissions in Diesel Engines is a pivotal reference source that provides vital research on technical and environmental enhancements to the emission and combustion characteristics of diesel engines. While highlighting topics such as biodiesel emulsions, nanoparticle additives, and mathematical modeling, this publication explores the potential additives that have been incorporated into the performance of diesel engines in order to positively affect the environment. This book is ideally designed for chemical and electrical engineers, developers, researchers, power generation professionals, mechanical practitioners, scholars, ecologists, scientists, graduate students, and academicians seeking current research on modern innovations in fuel processing and environmental pollution control.

Rheology of Emulsions, Volume 22: Electrohydrodynamics Principles studies phenomena at liquid-liquid interfaces, including finely dispersed particles or structures, in particular emulsions, double emulsions and biological cells. The book considers the forces of electrical origin that participate in the physical events at liquid-liquid interfaces, taking into account electron transfer phenomenon and electrodynamics principles. Topics covered are of interest to a broad range of scientists, researchers and graduate students with a basic knowledge of physical chemistry, electromagnetism, fluid mechanics, classical and quantum electrodynamics. The implications and applications of the material presented in the book contribute to the advanced fundamental, applied and engineering research of interfacial electroviscoelastic phenomena.

Bridging Scales in Modelling and Simulating Reacting Flows, Part I , Volume 52 presents key methods to bridge scales in the simulation of reacting single phase flows. New sections in the updated release include topics such as quadrature-based moment methods for multiphase chemically reacting flows, the collaboration of experiments and simulations for the development of predictive models, a simulation of turbulent coalescence and breakage of bubbles and droplets in the presence of surfactants, a section on salts and contaminants, and information on the numerical simulation of reactive flows.

Progress and Recent Trends in Microbial Fuel Cells provides an in-depth analysis of the fundamentals, working principles, applications and advancements (including commercialization aspects) made in the field of Microbial Fuel Cells research, with critical analyses and opinions from experts around the world. Microbial Fuel cell, as a potential alternative energy harnessing device, has been progressing steadily towards fruitful commercialization. Involvements of electrolyte membranes and catalysts have been two of the most critical factors toward achieving this progress. Added applications of MFCs in areas of bio-hydrogen production and wastewater treatment have made this technology extremely attractive and important. .