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A Practical Approach to Toxicological Investigations (Paperback)
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A Practical Approach to Toxicological Investigations (Paperback)
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First published in 1989, this book acknowledges that new drugs,
food additives and other compounds need to be carefully screened
for toxic side-effects. The bulk of this study is devoted to the
practical questions of 'what toxicological studies should we
perform?' and 'how should we perform them?' Compounds which undergo
toxicity testing may be conveniently categorised as those which are
intended for administration to man and those which are not. The
former include pharmaceuticals to be used medicinally or
prophylactically and chemicals which are added to our food, drinks
or medicine to improve their stability, appearance or palatability.
Since it is on pharmaceuticals that the most comprehensive
toxicological evaluations are generally performed, this book has
been directed primarily towards to toxicological evaluation of
potential new drugs. The principles and methodology of
toxicological evaluation of other types of compounds are
essentially similar.
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