"Evolution by Tumor Neofunctionalization" explores the
possibility of the positive role of tumors in evolution of
multicellular organisms. This unique perspective goes beyond recent
publications on how evolution may influence tumors, to consider the
possible role of tumors in evolution.
Widespread in nature tumors represent a much broader category
than malignant tumors only. The majority of tumors in humans and
other animals may never undergo malignant transformation. Tumors
may differentiate with the loss of malignancy, and malignant tumors
may spontaneously regress. Cellular oncogenes and tumor suppressor
genes play roles in normal development. Many features of tumors
could be used in evolution, and there are examples of tumors that
have played a role in evolution.
This book will stimulate thinking on this topic by specialists
in the fields of evolutionary biology, oncology, molecular biology,
molecular evolution, embryology, evo-devo, tumor immunology,
pathology and clinical oncology.
Covers the role that tumors might play in evolution.Provides
multidisciplinary approach that will appeal to a wide circle of
professionals in the fields of evolutionary biology, oncology,
molecular biology, and more
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