The book gives an account of results obtained from experiments
where grafts of neuronal, glial and other tissues as well as
artificial materials were placed into the spinal cord. It attempts
to evaluate the contributions made by these studies to our
understanding of basic neurobiologies questions. These include
factors that regulate neuronal growth during development as well as
regenera tion following injury to the nervous system. The model of
neural transplanta tion is also useful for the study of
cell-to-cell interactions, and this applies to interactions between
glial cells and neurones, between various populations of neuronal
cells and finally between axons and skeletal muscle fibres. The
mecha nisms involved in the establishment of specific synaptic
connections between neurones can also be investigated in this
experimental paradigm. Important in formation regarding this issue
was also obtained on systems other than the spinal cord, i. e. the
cerebellum, hippocampus and striatum. Although such in formation of
precise connections between the host and the grafted embryonic
tissue is still lacking in the spinal cord, there is much
information on the re sponse of the host nervous system to the
grafted embryonic tissue, and that of the graft to its new host
environment. It appears that embryonic grafts are able to induce
repair processes follow ing injury to the nervous system.
General
Imprint: |
Springer-Verlag New York
|
Country of origin: |
United States |
Series: |
Neuroscience Intelligence Unit |
Release date: |
2006 |
First published: |
2006 |
Editors: |
Antal Nogradi
|
Dimensions: |
234 x 156 x 14mm (L x W x T) |
Format: |
Hardcover
|
Pages: |
150 |
Edition: |
2nd ed. 2006 |
ISBN-13: |
978-0-387-26355-7 |
Categories: |
Books >
Medicine >
Surgery >
Transplant surgery
|
LSN: |
0-387-26355-1 |
Barcode: |
9780387263557 |
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