Patients who have problems in swallowing encounter difficulties in
taking tablets, particularly pediatric and geriatric patients. Such
problems can be resolved by means of orodispersible tablets. These
tablets disintegrate instantaneously when put on tongue, releasing
the drug that dissolves or disperses in the saliva.Metronidazole is
active against a wide variety of anaerobic protozoal parasites and
anaerobic bacteria.The present study aim to prepare tablets that
can rapidly disintegrate in oral cavity (orodispersible), another
challenge with this model drug is to mask the bitter taste. Taste
masking was achieved by using aminoalkyl methacrylate copolymer
(Eudragit E-100) in the different ratio (1:2 and 1:3) by extrusion
technique. The IR shows that there was no significant evidence for
interaction between drug and polymers. Six formulations were
prepared using taste masked granules and different disintegrants
(LH-11) and Avicel PH-102 by varying concentration.
General
Is the information for this product incomplete, wrong or inappropriate?
Let us know about it.
Does this product have an incorrect or missing image?
Send us a new image.
Is this product missing categories?
Add more categories.
Review This Product
No reviews yet - be the first to create one!