Now in its third edition, Pharmacology in Clinical Practice has been updated to ensure it remains up-to-date and relevant.

Particular care has been taken to simplify and clarify difficult concepts by explaining the links between pharmacology and physiology by providing definitions of new concepts, and using plain language for ease of understanding. Fundamental concepts, such as pharmacodynamics and pharmacokinetics, are well covered in a matter that is accessible and clear. Individual chapters cover the various systems of the body.

Updates include:

• A colour plate to illustrate the links between pharmacology and physiology
• Additional information on side-effects, contra-indications and patient education for groups of drugs
• A guide on how to access this information, to assist with exam preparation and nursing practice
• An updated chapter on nursing management of drug preparations and treatment
• An updated chapter on clinical applications
• A chapter on the legal framework for dispensing and prescribing.

THE DEFINITIVE GUIDE TO CANNABIS AND YOUR HEALTH Underpinned by his two-year research trial in partnership with the Royal College of Psychiatrists, involving up to 20,000 patients, which will create Europe's largest body of evidence on the plant's medicinal qualities - Professor David Nutt and his team of scientists will break the mould on the way we use Cannabis for our health in the future. In David's first ground-breaking book on the subject, he will cover its impact of all areas of the body and the brain and its effective use for treatment of illness from chronic pain, epilepsy, multiple sclerosis and PTSD, to anxiety and depression. This is the essential knowledge that cuts through the noise and give us evidence-based information that will change people's lives.

Despite the lack of guidance available for practitioners, extensive polypharmacy has become the primary method of treating patients with severe and chronic mood, anxiety, psychotic or behavioral disorders. This ground-breaking new book provides an overview of psychopharmacology knowledge and decision-making strategies, integrating findings from evidence-based trials with real-world clinical presentations. It adopts the approach and mind-set of a clinical investigator and reveals how prescribers can practice 'bespoke psychopharmacology', tailoring care to the individualized needs of patients. Practitioners at all levels of expertise will enhance their ability to devise rationale-based treatments, targeting manifestations of dysfunctional neural circuitry and dimensions of psychopathology that cut across conventional psychiatric diagnoses. Presented in a user-friendly, practical, full-colour layout and incorporating summary tables, bullet points, and illustrative case vignettes, it is an invaluable guide for all healthcare professionals prescribing psychotropic medications, including psychiatry specialists, primary care physicians, and advanced practice registered nurses.

This key volume of the Target Organ Toxicology Series provides a fresh and modern approach to the subject of skin toxicology from the perspective of how the skin forms a barrier that protects the body from the external environment and how chemicals and drugs interact with the barrier properties of the skin. Any defects or perturbations to this barrier may result in damage to the skin or may alter absorption. With contributions from over 40 international experts in the field of skin biology, the book presents the central role of the skin barrier to health and disease reviewing; The skin's anatomy and physiology, with focus on the stratum corneum as a barrier to foreign substances. Dermal absorption, cutaneous metabolism, and epidermal transporters. Altered barriers, racial skin types, aged skin, photoaged skin, cosmetics and skin sensitization. Modern approaches to drug delivery across the skin barrier, including liposomes, microneedle technology, active and passive transdermal delivery. Examples and case studies of chemical toxicity after topical exposures ranging from arsenic, metal working fluids, bromine, jet fuel, sulfur mustard and including the emerging area of nanomaterial penetration. Toxicology of the Skin is essential reading for drug delivery pharmacologist, formulation scientists, dermatologists, toxicologists, molecular biologists, engineers, surgeons, students and anyone interested in skin irritation and skin absorption.

Volksgeneeskuns in Suid-Afrika is ’n versameling van 8705 boererate en het die eerste keer in 1965 verskyn. Vandag, 60 jaar later, lyk die mediese en farmakologiese landskap totaal anders. Daarom is dit so interessant – en soms lagwekkend – om te sien hoe vinnig ons mediese en farmakologiese kennis intussen gevorder het.

Die versameling bevat rate wat op bygeloof of tradisionele mondelinge oorlewering berus. Ander rate maak staat op veldkennis en die botaniese name van middels word verstrek. Daar word raat uitgedeel vir kwale van asma tot ylhoofdigheid.

“Vermaaklike oomblikke is talryk vir die moderne leser – en die algemene gebruik van hondebloed, velle van pas geslagte katte, luislange en dies meer, laat ’n mens verbysterd – tot jy besef met hoeveel radeloosheid daar voor sekere siektes te staan gekom is.” Dr. Dione Prinsloo – geskiedkundige.

The 2022 edition of Rules and Guidance for Pharmaceutical Manufacturers and Distributors, known as 'The Orange Guide', is the essential reference for all manufacturers and distributors of medicines in the UK.It provides you with a single authoritative source of European and UK guidance, information and UK legislation relating to the manufacture and distribution of human medicines, active substances, and brokering medicines.The new 11th edition has been updated to incorporate changes made after the UK's exit from the European Union on the 31st January 2020

Medicines, Ethics and Practice is the Royal Pharmaceutical Society's established professional guide for pharmacists.This 45th edition is a revised practical resource which helps pharmacists practice confidently and professionally. It embeds professionalism at the heart of decision-making processes and provides essential information, supporting the pharmacist in their day-to-day practice

This new 12th edition of Dale and Appelbe's Pharmacy and Medicines Law is your guide to law and ethics for pharmacy practice in the UK. It covers law and professional regulation and is firmly established as the definitive student textbook and reference work on this subject in the UK. This edition has been extensively restructured and revised to include all the most recent changes to pharmacy laws and regulation.

The British National Formulary for Children is the first choice for concise medicines information for children. Trusted by healthcare professionals across the world to support confident decision-making at the point of care. The new edition provides up-to-date guidance on prescribing, dispensing, and administering medicines to children, plus legal and professional guidelines. Recommendations in the BNF for Children have been constructed on the basis of authoritative sources, emerging evidence, best practice guidelines and advice from a network of paediatric experts. The process is overseen by a paediatric formulary committee.

Ready to master the medication process? Tap into the go-to resource for nursing pharmacology basics, with the fully updated new fifth edition of Pharmacology Made Incredibly Easy! (R). Offering clear, concise descriptions of crucial nursing pharmacology concepts and procedures, this easy-to-follow, colorfully illustrated guide offers step-by-step guidance so to can grasp the fundamentals in enjoyable Incredibly Easy style. From initial assessment to safe medication administration and patient care plans, this is the perfect supplement to class materials, offering solid preparation for NCLEX (R), as well as a handy refresher for experienced nurses. Learn the ins and outs of nursing pharmacology care, with the latest data and protocols: NEW chapters on patient education, sensory drugs, and dermatologic drugs NEW chapter on medication safety, including abbreviations to avoid and a review of dosage calculations NEW content on current approved medications and dosages, and expected versus adverse effects NEW content on emergency drugs, herbs/supplements, immunization schedule, and more Hundreds of colorful diagrams, drawings, and charts that illustrate core concepts, with easy-to-retain definitions and clear direction on administering drugs; drug distribution, absorption, and metabolism; drug classes and their uses; and potential drug interactions Quick-scan outline format offers up-to-date guidance on areas including: Nursing pharmacology fundamentals Concepts of pharmacokinetics, pharmacodynamics, and pharmacotherapeutics Pain drugs, autonomic nervous system drugs, neurologic and neuromuscular drugs Psychotherapeutic, anti-infective, anti-inflammatory, anti-allergy, and immunosuppressant drugs Antineoplastic drugs, drugs for fluid and electrolyte balance Ways a drug may affect patients of different ages and other warnings Content reflects the NCSBN Clinical Judgment Measurement Model - guidance from initial assessment to evaluating outcomes "Practice Makes Perfect" end-of-book practice exam - approximately 100 new NCLEX (R)-style questions, to increase your exam confidence Chapter features include: Prototype pro - Actions, indications, and nursing considerations for common prototype drugs A three-step process is provided throughout the chapters to help you care for individuals taking commonly prescribed medications Pharm function - Explains and illustrates how drugs act in the body, and addresses how to recognize and treat adverse reactions Before you give that drug - Warnings to consider before you administer a drug Education edge - Information to share with your patient Black Box Warnings boxes draw attention to life-threatening concerns Lifespan Lightbulb boxes highlight information about how a drug or drug class may affect patients of different ages Quick quiz - End-of-chapter questions with answers/explanations, to help you remember the essentials Nurse Joy and Jake illustrated characters offer tips and insights throughout About the Clinical Editors Cherie R. Rebar, PhD, MBA, RN, CNE, CNECI, COI, FAADN, is a Professor of Nursing at Wittenberg University in Springfield, Ohio Nicole Heimgartner, DNP, MSN, RN, CNE, CNECI, COI, is a Nursing Faculty member at Galen College of Nursing in Louisville, Kentucky Carolyn Gersch, PhD, MSN, RN, CNE, is a Professor of Practice in the Nursing Program at Wittenberg University in Springfield, Ohio

Approaches skin disorders morphologically. Emphasises on key diagnostic clinical points. Includes different presentations of common skin conditions. Emphasises on common clinical conditions presenting in a routine OPD. Includes good quality clinical photographs.

The 2022 edition of the Rules and Guidance for Pharmaceutical Distributors, the 'Green Guide', is the essential reference for all distributors, brokers of human medicines, importers and distributors of active substances in the UK.It provides you with the single authoritative source of European good distribution practices and UK guidance, information and UK legislation on these activities.The new 5th edition has been updated to incorporate changes made after the UK's exit from the European Union on the 31st January 2020.It also incorporates new guidance on pharmacovigilance for wholesalers, the naming of sites on a licence, self-inspection, and the responsible person for import.It brings together EU guidance on good distribution practice and the MHRA's expectations for compliance. There is also a new flowchart for the registration of handling active substances

THE DEFINITIVE GUIDE TO THE NEW SCIENCE OF PSYCHEDELICS. Psychedelics are big news. From micro-dosing to mushroom clinics to celebrity-endorsed ayahuasca retreats in Peru, they are moving ever more into mainstream consciousness. But psychedelics are also set to change the face of medicine, our treatment for mental health conditions like depression, and our understanding of the human brain. Rooted in his team's world-leading research in the brain imaging of psychedelics, as well as years of hands-on experience treating patients, in Psychedelics Professor David Nutt will correct myths and misconceptions, equip us with the information to make informed decisions, and answer all your questions about this medical revolution.

Drugs in Use: Case Studies for Pharmacists and Prescribers helps you to bridge the gap between theoretical knowledge about medicines and the practical application to your patients. The sixth edition of this popular text has been extensively revised to ensure that a primary care focus is included whenever possible, in order to reflect the fact that drug management of chronic conditions increasingly takes place in primary care, and that this is an expanding role for pharmacists working in GP surgeries. There are new chapters on atrial fibrillation, chronic asthma, general surgery, sepsis, deprescribing and supporting adherence.

The Maudsley(R) Prescribing Guidelines in Psychiatry The new edition of the world-renowned reference guide on the use of medications for patients presenting with mental health problems The Maudsley Prescribing Guidelines in Psychiatry is the essential evidence-based handbook on the safe and effective prescribing of psychotropic agents. Covering both common and complex prescribing situations encountered in day-to-day clinical practice, this comprehensive resource provides expert guidance on drug choice, minimum and maximum doses, adverse effects, switching medications, prescribing for special patient groups, and more. Each clear and concise chapter includes an up-to-date reference list providing easy access to the evidence on which the guidance is based. The fourteenth edition has been fully updated to incorporate the latest available research, the most recent psychotropic drug introductions, and all psychotropic drugs currently used in the UK, USA, Canada, Australia, New Zealand, and Japan. Several new sections cover topics such as deprescribing of major psychiatric drugs, prescribing psychotropics at the end of life, the treatment of agitated delirium, the genetics of clozapine prescribing, the use of weekly penfluridol, and the treatment of psychotropic withdrawal. Featuring contributions by an experienced team of psychiatrists and specialist pharmacists, the new edition of The Maudsley Prescribing Guidelines in Psychiatry Provides succinct coverage of drug treatment of psychiatric conditions and formulating prescribing policy in mental health Covers a wide range of psychiatric conditions including schizophrenia, bipolar disorder, depression and anxiety, borderline personality, eating disorders, and many others Provides advice on prescribing for children and adolescents, older people, pregnant women, and other special patient groups Offers new sections on genetic prescribing, long-acting injectable formulations, ketamine administration and uses, and dopamine super-sensitivity Includes referenced information on off-label prescribing, potential interactions with other substances such as alcohol, tobacco, and caffeine, and treating patients with comorbid physical conditions Whether in the doctor's office, in the clinic, or on the ward, The Maudsley Prescribing Guidelines in Psychiatry, Fourteenth Edition is a must-have for psychiatrists, pharmacists, neuropharmacologists, clinical psychologists, nurses, and other healthcare professionals working in mental health, as well as trainees and students in medicine, pharmacy, and nursing.

Macrocyclic lactones are chemical compounds that represent the main treatment for parasitic diseases of animals, not only for helminth infections, but also a number of major ectoparasitic infestations. There has been no comprehensive book on this subject for more than a decade and this book fills this gap and provides detailed coverage of the basic science of these drugs and their mode of action, as well as their clinical use in farm and companion animals and in humans.

Project managers in drug development are the driving force behind the coordination of efforts. This book provides a practical reference for project managers in the pharmaceutical and biotech drug development industry, with the goal of assisting in creating an efficient and effective team structure and environment. The text details the role of project managers at each stage of drug development, the key interfaces that the PM will need to work closely with, and essential tools of the trade including frequently used techniques and methodologies. This book is useful for both entry-level and advanced-level PMs, as well as non-project managers from other functions. Features Includes authors' recent experience with improved tactics and technologies/software at various stages of drug development. Provides the most up-to-date and best practices, techniques, and methodologies in project management. Details the role of the PM at each stage of drug development, including working with the key interfaces throughout the process. Diverse audience including nonproject managers in clinical development, clinical operations, regulatory affairs, medical affairs, clinical pharmacology, and biostatistics. Provides templates and timelines for critical paths from development to commercialization and has potential as a textbook on relevant courses.

"Pharmaceutical Pharmacology", encompassing 78 chapters, is divided into four major comprehensive parts. Part A deals with general pharmacology, pharmacology of peripheral nervous system and pharmacology of central nervous system. Part B is concerned with pharmacology of cardiovascular system, drugs acting on the hemopoetic system, drugs acting on the urinary system, autocoids and drugs acting on the respiratory system. Part C contains chapters on drugs acting on the gastrointestinal tract, pharmacology of endocrine system, chemotherapy and principles of toxicology. Part D discusses mainly clinical pharmacy, pharmacotherapy, important disorders of organ system and their management, therapeutic drug monitoring and concept of essential drugs and rational drug use.To provide a realistic approach to the understanding of the subject, each chapter commences with a crisp introduction followed by classification, treatment of each class of drugs with reference to important 'drugs' vis-a-vis pharmacological actions, pharmacokinetic actions, mechanism of action, therapeutic uses, dosage regimens, adverse drug reactions, drug interaction, etc. The text is profusely illustrated with labelled diagrams, graphics and lucid explanations. It provides the reader an explicit route starting from the molecular understanding of receptors and drug activities to the therapeutic applications of the most important class of drugs.

This book summarizes the development and statistical validation of a guinea pig model as an alternative for potency testing of the viral antigens included in combined vaccines applied in cattle to control the respiratory, reproductive, and neonatal calf diarrhea syndromes. The model allows, in one serum sample, to test the vaccine quality for all the viral antigens included in aqueous as well as in oil-adjuvanted formulations of bovine vaccines. The methodology proposed for the control of bovine herpes virus, parainfluenza, and rotavirus were recommended by CAMEVET as guidelines for the 30 countries in the forum, including the US. Key Features Reviews combined vaccines used for cattle Summarizes animal models used for vaccine testing Focuses on bovine herpesviruses, rotaviruses, parainfluenza, and bovine viral diarrhea virus Provides guidance on the effectiveness of the Guinea Pig model for testing vaccine immunogenicity

Phytopharmaceuticals and Herbal Drugs: Prospects and Safety Issues in the Delivery of Natural Products explores the delivery aspects of plant-based drugs, providing insights into formulation constraints associated with plant-based drugs, the development of novel delivery systems based on polymers or lipids, and how combining natural products with technological advancements in drug delivery is making large strides. Some of the best-selling drugs for the treatment of diseases like cancer, ulcers and malaria are either natural products or their derivatives, all of which are covered in this comprehensive resource. This book will be useful to researchers working in plant-derived medicines and the development of their delivery systems, including sections on their derivatives and analogs that represent over 50% of all drugs in clinical use. Active ingredients originated from plant resources generally exhibit compromised desired effects limited by issues such as stability, solubility, molecular size, bioavailability and toxicity.

There have been a number of significant changes in transfusion science in the last five to ten years and this second edition of Transfusion Science covers these in some detail. * A new chapter introduces readers to the current applications of emerging techniques in transfusion science. * Platelet immune disorders and haemolytic anaemias are now covered. * The need for leucodepletion and methods for pathogen reduction are described. * The latest nomenclature for blood group genes has been adopted. * Current practice in blood group serology is reviewed. * Recent legislative changes for quality assurance in transfusion in the UK are now also covered. Case studies and colour photographs are now provided to illustrate concepts and to aid understanding, and a revised series of self-assessment questions and learning outcomes are also provided. An understanding of transfusion science is vital for all biomedical science students. Transfusion Science, second edition, explains all the basic principles alongside descriptions of the applications now possible as a result of modern analytical techniques. This book is essential reading for all students studying courses on transfusion and transplantation.