The growth in chemotherapy has led to a great need for all those involved to be familiar with safe procedures based on best evidence-based practice. Practical Chemotherapy: a multidisciplinary guide is a comprehensive and straightforward guide describing over 70 widely used chemotherapy regimens, helping to make their prescription and administration safer and less problematic. Checklists throughout the book are specifically tailored for the needs of each professional group involved in treatment, and are intended to help prevent potentially serious mistakes that can occur. This book is unique in its practical emphasis and will be invaluable for doctors, pharmacists and nurses working in oncology and haematology.

How do plant compounds affect our bodies? Plants defend themselves from other organisms through the production of bioactive metabolites. Introduced to the body, these compounds bind to particular biochemical targets, most notably to proteins involved in signalling by hormones and neurotransmitters. This, essentially, is the basis for the effects of herbal medicine. Though whilst herbal medicine preparations may act by complex synergistic interactions, molecular explanations of herbal medicine efficacy and side-effects will ultimately require definition of the biochemical targets of individual plant bioactive constituents.
This volume is a comprehensive and user-friendly reference guide to biochemical targets of plant defensive compounds. It presents a mine of succinctly summarized information relating to bioactive compound structures, plant sources, biochemical targets and physiological effects which can be readily accessed via the plant genus index and chemical compound index. With introductory chapters providing reviews of the structural diversity of plant defensive compounds and biochemistry, Biochemical Targets of Plant Bioactive Compounds is an invaluable reference for biomedical professionals in the fields of complementary medicine, natural product chemistry, toxicology and pharmacology.

eBook available with sample pages: 0203013719

This could be the most important book you will read this year. Around the office at Chelsea Green it is referred to as the "pharmaceutical Silent Spring." Well-known author, teacher, lecturer, and herbalist Stephen Harrod Buhner has produced a book that is certain to generate controversy. It consists of three parts: 1. A critique of technological medicine, and especially the dangers to the environment posed by pharmaceuticals and other synthetic substances that people use in connection with health care and personal body care.2. A new look at Gaia Theory, including an explanation that plants are the original chemistries of Gaia and those phytochemistries are the fundamental communications network for the Earth's ecosystems.3. Extensive documentation of how plants communicate their healing qualities to humans and other animals. Western culture has obliterated most people's capacity to perceive these messages, but this book also contains valuable information on how we can restore our faculties of perception.The book will affect readers on rational and emotional planes. It is grounded in both a New Age spiritual sensibility and hard science. While some of the author's claims may strike traditional thinkers as outlandish, Buhner presents his arguments with such authority and documentation that the scientific underpinnings, however unconventional, are completely credible.The overall impact is a powerful, eye-opening expos' of the threat that our allopathic Western medical system, in combination with our unquestioning faith in science and technology, poses to the primary life-support systems of the planet. At a time when we are preoccupied with the terrorist attacks and the possibility ofbiological warfare, perhaps it is time to listen to the planet. This book is essential reading for anyone concerned about the state of the environment, the state of health care, and our cultural sanity.

Linum usitatissimum is a widely distributed plant that has a long history of traditional use as both an industrial oil and fibre crop. It is known as linseed in the United kingdom and its former colonies, or flax in North America. For the last fifteen year there has been a steadily growing interest in the medicinal and nutraceutical value of flax, including experimental evidence for the role of flax lignans in the prevention of cancer as well as cardiovascular and kidney diseases.
This volume is a comprehensive review of the genus covering all aspects of the taxonomy, chemistry, cultivation, pharmacology and commercial uses of flax, and includes chapters on the disease prevention potential of these plants. With material written by leading experts, this book will be an invaluable reference source to all those interested in nutraceuticals, medicinal plants, pharmacy and agronomy.

eBook available with sample pages: 0203437500

This new, and heavily revised, edition of Psychopharmacology, provides a comprehensive scientific study of the effects of drugs on the mind and behaviour. With the growing prevalence of psychiatric and behavioral disorders and the rapid advances in the development of new drug therapies, this textbook offers an essential understanding of the necessary details of drug action. The book presents its coverage in the context of the behavioral disorders they are designed to treat, rather than by traditional drug classifications, to strengthen understanding of the underlying physiology and neurochemistry, as well as the approaches to treatment. Each disorder from the major diagnostic categories is discussed from a historical context along with diagnostic criteria and descriptions of typical cases. In addition, what we presently know about the underlying pathology of each disorder is carefully described. Providing a solid foundation in psychology, neuroanatomy and physiology, the book also offers a critical examination of drug claims, as well as coverage of evidence-based alternatives to traditional drug therapies. Throughout, this text discusses how drug effectiveness is measured in both human and animal studies. Topics new to this edition include: a stronger emphasis on the environmental impacts on drug effectiveness; more on the mechanisms of adverse reactions to drugs and information on managing drug side effects; the risks and benefits of using "mood stabilizing drugs" to address behavior in youth with ADHD or ASD; and discussion of the research-to-practice gap in pharmacological care for children and adolescents. Accompanied by a robust companion website of instructor materials, this textbook is ideal for undergraduate and pre-professional students on courses in Psychopharmacology, Clinical Psychopharmacology, Drugs and Behavior. It is a valuable contribution to highlight the symbiotic relationship between psychopharmacology and the neural and behavioral sciences.

This up-to-date reference book discusses the synthesis, production, and application of various microbial enzymes and metabolites for health. Microorganisms like bacteria (lactic acid bacteria, Bacillus species), yeasts, and filamentous fungi have been globally exploited for their biotechnological applications. This book discusses ways to use them commercially. Chapters include the production of fibrinolytic enzymes, microbial lipases, bacteriocin production by lactic acid bacteria, and bioactives produced. It also covers microbial synthesis of alkaloids, terpenoids, and steroids. The book is useful for researchers, academicians, and industry experts in microbiology and biotechnology.

Introducing Palliative Care is the ideal introductory text for training students in medicine and qualified healthcare professionals in the area of palliative care. The sixth edition has been fully revised in line with current practice and the latest edition of the Palliative Care Formulary (PCF7).

Marijuana is the prototypical cannabinoid, and is one of the most widely used drugs in the world. Cannabinoids are molecules found naturally in the human body and brain as well as in cannabis.
This book provides an extensive reference on the biology of marijuana and the role of molecular techniques in elucidating neuropharmacological aspects of cannabinoid receptors and the endogenous compounds that act upon them. Contributions from experts from around the world describe the interaction of cannabinoids and endocannabinoids on a wide range of biological functions including movement, memory and learning, pain, emotions, endocrine functions and many more. The Biology of Marijuana will be of interest to all scientists and clinicians interested in the biological effects and pharmacology of this drug.

eBook available with sample pages: 0203219139

This book focuses on the aerosol treatment of lung diseases, recent improvements in the understanding of proper dosage, and major innovations in device technology applied to clinical practice.
Examines the behavior of inspired spherical particles in the respiratory tract
Featuring over 1300 references, drawings, tables, photographs, and micrographs, Drug Delivery to the Lung
outlines the history of inhaled medications in the treatment of respiratory disease
describes aspects of respiratory structure to inhalation therapy emphasizing developmental changes
compares existing in vitro/in vivo correlations for key aerosol modalities with lung model predictions
discusses particle diameter measurement, particle size statistics, and aerosol test methods
reviews the clinical effects of altering the deposition site of various classes of aerosolized drugs
surveys the development of novel, efficient, and convenient nebulizer systems
details breath-actuated and spacer devices constructed for children
analyzes dry-powder and pressurized metered dose inhalers
considers the transition from CFCs to new environmentally friendly chemical propellants
and more
Giving the clinician an overview of factors essential to understanding drug delivery via nebulization, Drug Delivery to the Lung is a superlative reference for pulmonologists; physiologists; pharmaceutical scientists; immunologists; allergists; analytical, organic, and medicinal chemists and biochemists; chemical, genetic, and process engineers; and medical and graduate school students in these disciplines.

Contents:
1. Shengmai San - A Renowned Traditional Chinese Medicine 2. Pharmacological Studies on Shengmai San 3. Clinical Studies on Shengmai San 4. Side Effects of Shengmai San 5. Phytochemistry and Pharmacology of Component Herbs of Shengmai San 6. Contemporary Applications of a Traditional Formula: Manufacturing of Shengmai San (SMS) Preparations and their Applications

The tea plant, Camellia sinensis, is of particular importance to humans, and the consumption of tea has a long history of over 2000 years. Currently, tea is one of the most popular beverages worldwide. In recent years the subject of tea has attracted a great deal of attention, As well as the use of tea in traditional medicine, modern biochemical research has shown the potential application of tea and tea products to disease prevention and therapy.
The goal of his book is to cover all relevant aspects including botanical identification, processing and major categories of tea, physiological and pharmacological effects, and experimental therapeutic effects. The therapeutic applications of tea based on traditional Chinese medicine are also included. The contributors are renowned experts from botanical, agricultural, chemical, biochemical, and medical circles. Tea will be an invaluable reference source for physicians and all professionals in pharmaceutical, agricultural, and food research and development industries as well as anyone who is interested in the potential medical applications of tea.

eBook available with sample pages: 0203301277

Multivariate Analysis in the Pharmaceutical Industry provides industry practitioners with guidance on multivariate data methods and their applications over the lifecycle of a pharmaceutical product, from process development, to routine manufacturing, focusing on the challenges specific to each step. It includes an overview of regulatory guidance specific to the use of these methods, along with perspectives on the applications of these methods that allow for testing, monitoring and controlling products and processes. The book seeks to put multivariate analysis into a pharmaceutical context for the benefit of pharmaceutical practitioners, potential practitioners, managers and regulators. Users will find a resources that addresses an unmet need on how pharmaceutical industry professionals can extract value from data that is routinely collected on products and processes, especially as these techniques become more widely used, and ultimately, expected by regulators.

This volume examines the Middle East's leading armed forces and their role in both military and political affairs. It considers their missions, doctrine, training, equipment and effectiveness as fighting forces. At the same time, the various expert contributors discuss the relations between the armed forces and their respective governments, with the issues raised ranging from internal repression to budgetary matters. On some issues, high-ranking officers force Arab regimes to meet their demands. In other ways, regimes impose restrictions on the armies in order to maintian their own political control. These mechanisms also reduce the soldiers' military quality, and hence their ability to wage war.
Among the armed forces specifically examined in this volume are those of Egypt, Iran, Iraq, Israel, Jordan, the Palestinian Authority, Syria and Turkey. Other chapters provide an overview of the Middle Eastern militaries' political role and strategic value; of why Arab armies have performed poorly in warfare; and of the part played by the United States and Russia in training, arms supplies, shaping the doctrine of local militaries, and engaging in direct intervention.

Neglected Diseases: Extensive Space for Modern Drug Discovery provides in-depth reviews on the last progresses about neglected tropical diseases research. Topics covered in this volume include Leishmaniasis, Tripanosomiasis, Onchocerciasis and Ebolavirus infections, with insights on the future of the research on them. Part of the volume is devoted to recent contributions this field received from X-Ray crystallography.

CRC Handbook of Phytochemical Constituents of GRAS Herbs and Other Economic Plants is a unique catalog that includes more than 15,000 phytochemical constituents from over 1,000 higher plant species. This volume covers all of the generally-recognized-as-safe (GRAS) herbs and at least 250 important food and medicinal plants. Each entry features the scientific name, one or more common names, a listing of phytochemical constituents, a single datum or range of quantitative data (wet-weight to dry-weight in parts per million), two-letter abbreviation identifying the plant part, and three-letter abbreviation(s) indicating the source(s) of the data.

The extraordinary amount of data compiled into an easy-to-use tabular format makes the CRC Handbook of Phytochemical Constituents of GRAS Herbs and Other Economic Plants a volume useful to all pharmacologists, toxicologists, nutritionists, pharmacognicists, and food scientists.

Sage, the Genus Salvia is one of the most famous and used herbs in the world. This volume, containing over twenty chapters written by leading experts in the field, presents a comprehensive coverage on all aspects of Salvia. Topics covered include the presentation of the most known Salvia species (approximately 400 of them), the distribution of the genus, its chemotaxonomy, ecophysiology, cultivation technology and breeding methods, information on the extraction, isolation, characterisation and structure of a large number of bioactive components, the various pharmacological properties of the species, the share of Salvia products in aromatherapy and the natural cosmetics market, biotechnological techniques, and commercial aspects.

This comprehensive volume on Salvia should be of interest to everyone involved in medicinal and aromatic plant applications and research.

Master key scientific principles to prepare for certification and practice as a Pharmacy Technician. Pharmacology for Pharmacy Technicians, 3rd Edition, is a comprehensive, yet approachable text written specifically for your needs and offering complete coverage of the principles of pharmacology and the way drugs work within the body's systems. Concepts are supplemented throughout with patient scenarios, anatomy and physiology refreshers, drug monographs with pill photos, and a number of other learning aids to help you comprehend this subject matter. With its companion workbook, this learning package provides the essential foundation necessary to launch a successful and rewarding career in Pharmacy Technology! Comprehensive, updated content is built to address the specific needs of Pharmacy Technician education. Mini drug monographs in every body system and drug classification chapter contain valuable drug information and pill photos for quick reference. Summary drug tables with generic/brand name, usual dose and dosing schedule, and warning labels offer at-a-glance access to information about specific drugs. Helpful Tech Notes enhance your understanding of the practical knowledge needed in the pharmacy setting and help you relate new concepts to practical use. Tech Alerts offer critical reminders and warnings to help you learn to identify and avoid common pharmacy errors. Technician's Corner critical thinking exercises prepare you for on-the-job situations by providing you with a set of facts and asking you to reach a conclusion. Updated drug information ensures you're familiar with the latest drug approvals and therapeutic considerations. Key terminology list with definitions feature visual highlights within chapter discussions, and alphabetized list in the glossary. UPDATED! Drug information reflects the latest dosage and prescription guidelines. NEW! Coverage of advancements in the areas of vaccines, HIV/AIDS, cancer, and diabetes provide you with the latest information for these chronic conditions. NEW! Additional artwork supports foundational and body-system pharmacology content. IMPROVED! Streamlined incorporation of med term and A&P content into chapters.

The Handbook of Pharmaceutical Controlled Release Technology reviews the design, fabrication, methodology, administration, and classifications of various drug delivery systems, including matrices, and membrane controlled reservoir, bioerodible, and pendant chain systems. Contains cutting-edge research on the controlled delivery of biomolecules! Discussing the advantages and limitations of controlled release systems, the Handbook of Pharmaceutical Controlled Release Technology -covers oral, transdermal, parenteral, and implantable delivery of drugs -discusses modification methods to achieve desired release kinetics -highlights constraints of system design for practical clinical application -analyzes diffusion equations and mathematical modeling -considers environmental acceptance and tissue compatibility of biopolymeric systems for biologically active agents -evaluates polymers as drug delivery carriers -describes peptide, protein, micro-, and nanoparticulate release systems -examines the cost, comfort, disease control, side effects, and patient compliance of numerous delivery systems and devices -and more!

The Opioid System as the Brain's Interface between Cognition and Motivation, Volume 239, focuses on the opioid system as the interface between the brain's cognitive and motivational systems. As the opioid system is widely distributed through the brain, particularly in areas implicated in cognition (hippocampus, prefrontal cortex, claustrum, thalamus) and motivation (hypothalamus, amygdala, pontine nuclei, periaqueductal gray and medulla), this book provides chapters that address ongoing research on topics such as the Brain's cognitive system, the Brain's motivational system, Antidepressant prescription patterns, Antidepressant-like effects of opioid receptor modulators, the Behavioral effects of antidepressant and anxiolytic drugs, and more.

This book provides a description on medicinal plants of Laos, including their role in maintaining health care among the population, their potential as a source for new medicinal compounds, their preservation, and their importance to the well being of the communities for present and future generations. The focus of this book is to draw on the rich culture, folklore, and environment of medicinal plants in the country. This is an opportunity to describe medicinal plants from a scientifically under-represented area, with the hope of being an important contribution to the knowledge of the region for both academics and scientists. Features Describes terrestrial medicinal plants from a scientifically under-represented region. Includes a wider variety of plants than previously published. Focuses on the rich culture, folklore, and environment of medicinal plants in Laos. Provides an important contribution to the knowledge of the region, and will benefit both academics and scientists in the field.

Medicinal Plant Responses to Stressful Conditions discusses the effects of multiple biotic and abiotic stressors on medicinal plants. It features information on biochemical, molecular, and physiological strategies used to mitigate or alleviate detrimental effects of biotic and abiotic stressors. The book contains chapters featuring medicinal plants of importance covering subjects including genomics, functional genomics, metabolomics, phenomics, proteomics, and transcriptomics under biotic and abiotic stress of medicinal plants and their molecular responses. It suggests exogenous application of different types of stimulants to enhance medicinal plant production in such conditions. Features: * Details all aspects of biotic and abiotic stressors in various important medicinal plant species. * Chapters cover evidence-based approaches in the diagnosis and management of medicinal plants under stressful conditions. * Includes information on ways to mitigate effects from high salinity, drought, temperature extremes, waterlogging, wind, high light intensity, UV radiation, heavy metals, or mineral deficiencies. A volume in the Exploring Medicinal Plants series, this book is an essential resource for plant scientists, botanists, environmental scientists, and anyone with an interest in herbal medicine

Counterfeit drugs continue to infiltrate the drug market in the United States, causing illness and death. This book addresses this issue and examines the recent trends in drug counterfeiting over the past 5-10 years. The text shows perspectives from crime lab and toxicology lab personnel and academic researchers, and includes topics such as a history of cases and issues with counterfeit drugs, trends observed in forensic labs, instrumental methods and approaches used in detecting counterfeit medicines, and policy approaches for controlling counterfeit drugs. There is a focus on ways to reduce counterfeit drugs in the market, to help improve the health and safety of people all over the world. Features : Focuses on recent (5-10) year trends in counterfeit drugs and analysis. Shows perspectives from crime lab and toxicology lab personnel and academic researchers. Focuses on drugs seized by law enforcement and approaches to reducing counterfeit medicine in the market. Discusses the detection and analysis of counterfeit drugs, and appropriate tools for combating this issue. Emphasizes the global impact of illegal medicines.

Filled with strategies to minimize the adverse effects of injectable drugs, this book provides the scientific background and techniques required to evaluate parenteral formulations with respect to their potential to cause pain, irritation, and muscle damage. Using a unique, interdisciplinary approach, the book's editors and contributors represent the areas of pharmaceutics, physiology, anatomy, toxicology, and product formulation. The chapters cover topics such as muscle damage with injectables, in vitro and in vivo cystolic enzyme release, histological and morphological methods, assessing pain, cosolvents in injectables, biodegradable microparticles, and more.

Quantitative Systems Pharmacology: Models and Model-Based Systems with Applications, Volume 42, provides a quantitative approach to problem-solving that is targeted to engineers. The book gathers the contributions of doctors, pharmacists, biologists, and chemists who give key information on the elements needed to model a complex machine like the human body. It presents information on diagnoses, administration and release of therapeutics, distribution metabolism and excretion of drugs, compartmental pharmacokinetics, physiologically-based pharmacokinetics, pharmacodynamics, identifiability of models, numerical methods for models identification, design of experiments, in vitro and in vivo models, and more. As the pharma community is progressively acknowledging that a quantitative and systematic approach to drug administration, release, pharmacokinetics and pharmacodynamics is highly recommended to understand the mechanisms and effects of drugs, this book is a timely resource.

Post-Authorization Safety Studies of Medicinal Products: The PASS Book bridges the gap in the literature by providing a complete look at post-authorization safety studies and important pharmacoepidemiology and pharmacovigilance aspects. It covers various types and limitations of active surveillance programs, including the use of large databases and disparate data sources for rapid signal detection, as well as novel and advanced design and analysis approaches for causal interference from observational data. This book serves as an important reference for pharmacovigilance scientists and pharmacoepidemiologists who are searching for the appropriate study design to answer safety research questions. Readers will be able to effectively and efficiently design and interpret findings from post-authorization safety studies with the goal of improving the benefit-risk balance of a drug in order to optimize patient safety.