Advanced Nanoformulations: Theranostic Nanosystems, Volume Three examines the applications of nanotherapeutic systems and nanodiagnostics in relation to polymeric nanosystems. In the last decade, numerous biopolymers have been utilized to prepare polymeric nanosystems for therapeutic applications. These biopolymers include polylactic acid, polylactide-co-glycolide, polycaprolactone, acrylic polymers, cellulose and cellulose derivatives, alginates, chitosan, gellan gum, gelatin, albumin, chontroitin sulfate, hyaluronic acid, guar gum, gum Arabic, gum tragacanth, xanthan gum, and starches. Besides these biopolymers, grafted polymers are also being used as advanced polymeric materials to prepare many theranostic nanocarriers and nanoformulations. This book explores the array of polymeric nanosystems to understand therapeutic potentials. It will be useful to pharmaceutical scientists, including industrial pharmacists and analytical scientists, health care professionals, and regulatory scientists actively involved in the pharmaceutical product and process development of tailor-made polysaccharides in drug delivery applications.

This book describes in detail the various teaching strategies and assessment methods used in pharmacy education. Included in the text is both the advantages and disadvantages of each teaching and assessment method, as well as tips for effective implementation of the strategies. The text covers a plethora of teaching styles, from web based and online learning to lecture and team-based learning, and highlights some of the best practices used worldwide. This book aims to be a valuable single resource for pharmacy educators, students, and researchers. Key features One resource for the pharmacy educators, students, partitioners, researchers, policy makers and other readers with the necessary information and practical guidelines about the online pharmacy education, practice, and research. Describe and discuss the situation of the online pharmacy education, practice, and research around the world. Describe the challenges facing the online pharmacy education, practice, and research and suggest recommendations to overcome the challenges. Describe the pharmacy education teaching strategies and assessment methods. Describe the advantages and disadvantages of each teaching strategy and assessment method. Provide tips for the effective implementation of teaching strategies and assessment methods based on the best practices worldwide.

This book describes in detail the various teaching strategies and assessment methods used in pharmacy education. Included in the text is both the advantages and disadvantages of each teaching and assessment method, as well as tips for effective implementation of the strategies. The text covers a plethora of teaching styles, from web based and online learning to lecture and team-based learning, and highlights some of the best practices used worldwide. This book aims to be a valuable single resource for pharmacy educators, students, and researchers. Key features One resource for the pharmacy educators, students, partitioners, researchers, policy makers and other readers with the necessary information and practical guidelines about the online pharmacy education, practice, and research. Describe and discuss the situation of the online pharmacy education, practice, and research around the world. Describe the challenges facing the online pharmacy education, practice, and research and suggest recommendations to overcome the challenges. Describe the pharmacy education teaching strategies and assessment methods. Describe the advantages and disadvantages of each teaching strategy and assessment method. Provide tips for the effective implementation of teaching strategies and assessment methods based on the best practices worldwide.

Tamoxifen Tales: Suggestions for Scientific Survival presents a case study describing the academic journey of teams behind major advances in medical sciences, highlighting lessons learned that are applicable to the next generation of scientists. This book provides a manual on the successful mentoring of young scientists, including stories describing how training experience shaped careers to become leaders in academia and the pharmaceutical industry. The book documents Professor V. Craig Jordan's 50-year career in medical sciences that led to the discovery and development of Selective Estrogen Receptor Modulators (SERMs), which became the standard of women's healthcare around the world. Additionally, it illustrates the versatility of a scientist with a commitment to serving societies. This important resource will be a useful and interesting book for established medical scientists, research mentors and advanced students wanting to chart a successful and impactful research career.

This new, and heavily revised, edition of Psychopharmacology, provides a comprehensive scientific study of the effects of drugs on the mind and behaviour. With the growing prevalence of psychiatric and behavioral disorders and the rapid advances in the development of new drug therapies, this textbook offers an essential understanding of the necessary details of drug action. The book presents its coverage in the context of the behavioral disorders they are designed to treat, rather than by traditional drug classifications, to strengthen understanding of the underlying physiology and neurochemistry, as well as the approaches to treatment. Each disorder from the major diagnostic categories is discussed from a historical context along with diagnostic criteria and descriptions of typical cases. In addition, what we presently know about the underlying pathology of each disorder is carefully described. Providing a solid foundation in psychology, neuroanatomy and physiology, the book also offers a critical examination of drug claims, as well as coverage of evidence-based alternatives to traditional drug therapies. Throughout, this text discusses how drug effectiveness is measured in both human and animal studies. Topics new to this edition include: a stronger emphasis on the environmental impacts on drug effectiveness; more on the mechanisms of adverse reactions to drugs and information on managing drug side effects; the risks and benefits of using "mood stabilizing drugs" to address behavior in youth with ADHD or ASD; and discussion of the research-to-practice gap in pharmacological care for children and adolescents. Accompanied by a robust companion website of instructor materials, this textbook is ideal for undergraduate and pre-professional students on courses in Psychopharmacology, Clinical Psychopharmacology, Drugs and Behavior. It is a valuable contribution to highlight the symbiotic relationship between psychopharmacology and the neural and behavioral sciences.

Smart Polymeric Nano-Constructs in Drug Delivery: Concept, Design and Therapeutic Applications provides a thorough discussion of the most state of the art material and polymer exploitations for the delivery of bioactive(s) as well as their current and clinical status. The book enables researchers to prepare a variety of smart drug delivery systems to investigate their properties as well as to discover their uses and applications. The novelty of this approach addresses an existing need of exhaustively understanding the potential of the materials including polymeric drug delivery systems that are smartly designed to deliver bioactive(s) into the body at targeted sites without showing side effects. The book is helpful for those in the health sector, specifically those developing nanomedicine using smart material-based nano-delivery systems. Polymers have unique co-operative properties that are not found with low-molecular-weight compounds along with their appealing physical and chemical properties, constituting the root of their success in drug delivery. Smart Polymeric Nano-Constructs in Drug Delivery: Concept, Design and Therapeutic Applications discusses smart and stimuli responsive polymers applicable in drug delivery, followed detailed information about various concepts and designing of polymeric novel drug delivery systems for treatment of various type of diseases, also discussing patents related to the field. The book helps readers to design and develop novel drug delivery systems based on smart materials for the effective delivery of bioactive that take advantage of recent advances in smart polymer-based strategies. It is useful to those in pharmaceutical sciences and related fields in developing new drug delivery systems.

Details all recently developed methods for palladium and platinum determination using spectrophotometry in a single source. Organized so that given so that anyone interested in a particular method using a specific reagent can go directly to those details. Facilitates the development of better methods for specific conditions of a sample.

Fully updated to reflect the nutritional needs of the '80s, this new edition of the classic guide to herbal medicine, natural foods and home remedies underscores the fundamental principle that true healing consists of a return to natural habits of living.

This important book introduces pharmacists and pharmacy students to the basics of disaster and emergency management, illustrating not only the different roles that pharmacists can play within any disaster or emergency, but the practical steps they can take to prepare for these events. Starting with the UN-recognised Sendai Framework for disaster risk reduction, the book introduces the key concepts and models that pharmacists should understand, before detailing the place of pharmacists within each stage of an emergency or disaster. It also includes interviews with experts in disaster management, shedding light not only on the place of pharmacy within disaster and emergency management, but also the challenges and barriers involved in fulfilling this role. Concluding with practical advice and guidance, as well as how the lessons of disaster and emergency management can inform the everyday role of pharmacists within wider community healthcare, this will be essential reading for both professionals and students in the field.

How Synthetic Drugs Work: Insights into Molecular Pharmacology of Classic and New Pharmaceuticals provides comprehensive, structured access to robust information on molecular pharmacology for clinicians, research scientists and advanced health care students. The book covers the foundations of molecular pharmacology and the main drug classes, including detailed information on their mechanisms of action and the application of molecular pharmacology in drug development. This book is an ideal reference for graduate students and researchers in pharmacology, however, researchers in corporate settings will also benefit from the book's structured and detailed coverage of mechanisms of action of synthetic drugs.

*Provides an accessible and concise aid to prescribing and monitoring systemic dermatologic therapy for all medical professionals involved in patient care *Enables dermatologists, family practitioners, pharmacists, and specialist nurses to make rational decisions about drug treatment while considering known risks and potential unwanted effects *Allows quick and easy access to reliable information with an international perspective

Key Features: 1. Describes the development of the randomized, controlled trial as the gold standard of proof. 2. Unravels the meaning of "randomized," "double-blind" and "p-values" in a simplified manner for students and clinicians. 3. Contains timeless information on how medical evidence can be understood.

Drug Delivery Systems for Metabolic Disorders presents the most recent developments on the targeted delivery of drugs to deal with metabolic disorders in a safe, compliant and continuous way. The book covers recent developments in advanced drug delivery systems in various metabolic disorders, including disturbances in protein, lipid, carbohydrate and hormone metabolism and lysosomal and mitochondrial disorders. It provides a brief introduction to metabolic disorders, along with a focus on the current landscape and trends in understanding disease pathology using different in vitro and in vivo models required for clinical applications and developments of new therapeutics. Each subsequent chapter covers drug delivery systems dedicated to metabolic diseases caused by disturbances in protein, lipid, carbohydrate and hormone metabolism. Then, it moves on to cover lysosomal storage disorders and applications of phytopharmaceuticals in this context. This is the perfect reference for researchers in pharmaceutical science who are interested in developing new treatments for metabolic diseases.

Targeted Nanomedicine for Breast Cancer Therapy provides a compilation of treatment approaches for breast cancer, including conventional receptor targeting methods and novel strategies like stimuli responsive methods and tumor micro-environment responsive strategies. This book compiles the most important information on the state-of-the-art therapeutics, including breast cancer biomarkers and design principles of bio-responsive nanosystems. Presented in two parts, sections cover basic and receptor mediated targeting approaches and examine tumor microenvironment mediated approaches. This is a useful book for pharmaceutical scientists and basic and clinical scientists working in the research area of breast cancer and drug discovery both from academics and industry. Worldwide, breast cancer is the most common cancer in women, however, breast cancer therapy is always challenging. This book aims to help researchers remain updated on the most targeted nanomedicine research available.

Presents a complex topic in a simple, easy-to-understand way Pocket Guide: Pharmacokinetics Made Easy is the latest update of the popular Pharmacokinetics Made Easy. It is suitable for a wide audience including medical practitioners, health professionals, and students. The individual chapters were initially published as a series of articles in Australian Prescriber to assist practitioners in drug dosing and therapy. The physiological approach herein adopted addresses clinical issues in drug therapy and makes them directly applicable to practice situations. Key Selling Features: - Self-assessment questions in each chapter - Glossary of symbols - Use of equations to explain physiological factors underlying important pharmacokinetics processes - Endorsed and co-published with Australian Prescriber - List of key points summarizing the content to improve accessibility and understanding

A must-have companion for medical students and junior doctors for almost four decades, Lecture Notes: Clinical Pharmacology and Therapeutics provides concise yet thorough coverage of the principles of clinical pharmacology, the major characteristics of therapeutics, and the practical aspects of prescribing drugs to alleviate symptoms and to treat disease. Whether you are preparing for examinations or prescribing to patients, the tenth edition offers readers current and authoritative insight into the essential practical and clinical knowledge. Logically organised chapters allow for rapid location of key information, while examples of commonly encountered scenarios illustrate how and when to use drugs in clinical situations. Throughout the text, practice questions, prescribing guidelines, and self-assessment tests clarify and reinforce the principles that inform appropriate clinical decision-making. Presents an up-to-date review of drug use across all major clinical disciplines Offers a timely overview of clinical drug trials and development Provides new clinical scenarios to relate chapter content to real-life application Contains colour-coded "Key Points" and "Prescribing Points" to highlight important information Includes chapter introductions and summaries, and numerous figures, tables, and colour illustrations Lecture Notes Clinical Pharmacology and Therapeutics, Tenth Edition, is an essential resource for medical students, junior doctors, and other prescribers looking for an up-to-date reference on pharmacological principles, prescribing, and therapeutics.

Biomedical Science Chinese herbal medicine represents complementary or adjunctive therapies that often can improve the efficacy of Western medicine to achieve the pharmacological effects, especially in cancer treatment. However, the combination of herbs with therapeutic drugs can raise potential health risk. Building a bridge between Western medicine and herbal medicines, Active Phytochemicals from Chinese Herbal Medicines: Anti-Cancer Activities and Mechanisms gives you useful information on how integrated medicines can work for cancer therapy. It discusses the therapeutic uses of phytochemicals, adverse effects, and interactions with (Western) cancer drugs. The author takes a unique approach to integrated pharmacology of herbal medicines, examining the development of phytochemicals and their mechanisms of action in the context of the cancers and diseases they are used to treat. He covers biologic action of the active phytochemicals at the molecular, cellular, and organ levels. The book covers the principles of the interaction of phytochemicals and the related drug actions. It also addresses the common pathways affecting cancer development before discussing the phytochemical classes and specific phytochemicals that have been recently reported in journal papers for the management of cancer and other diseases. Highlighting the increasingly important aspects of pharmacology, including health benefit and drawbacks of phytochemicals, the book presents the relevant background of the biochemistry of the cancer. It includes illustrations and tables with adverse reactions that highlight important issues related to phytochemical actions. These features and more make the book a useful reference on phytochemicals obtained from herbal medicines. It blends coverage of fundamental mechanisms of anti-cancer action and the use of phytochemicals to manage cancers and other human diseases, allowing you to explore how herbal medicines can enhance conventional protocols.

* The book is balanced and comprehensive, recognising that both affordability and investment into innovation are necessary * The book is original, using ecological concepts to understand pharmaceutical innovation as an ecosystem. * The book is unique in its research foundation, building on the views of more than 70 expert informants from all parts of the pharmaceutical innovation ecosystem and all sides of the debate about drug pricing.

Adults ages 65+: Your medication could be the reason for your new medical condition; read this eye-opening guide to become an expert on what medications you take! We have a medication problem in America. It is marked not only by excessive use of medications, but by errors in how they are prescribed, monitored, and taken. An estimated nineteen million adults age sixty-five and older take five or more medications daily. These individuals and family caregivers know the frustrations of lengthy medication lists, high drug costs, and frequent questions about the need and value of those medications. All too often, an unrecognized adverse drug effect is mistaken for a new medical condition, or worse, a symptom of getting older. But who stops to question the medications? Maybe It’s Your Medications tackles these problems by providing information, insider tips, and strategies that empower patients and caregivers to have important conversations about their prescription and nonprescription drugs. This book addresses the questions consumers want to ask about their medications and brings to light other questions they should be asking but may not know how. It is everyone’s go-to guide on how to use medications safely on the journey to healthy aging.   Dr. Hedva Barenholtz Levy, PharmD, is a geriatric specialist and founder of a unique senior care practice of over 25 years working with patients in their homes. She is an educator and leader in geriatric pharmacy and a dual board-certified specialist. Dr. Levy applies her decades of experience to guide the reader in how to become an active participant on their healthcare team and prevent unintended errors and medication-related problems.  

Systemic lupus erythematosus (SLE), commonly called lupus, is a chronic autoimmune disorder that can affect virtually any organ of the body. In lupus, the body's immune system, which normally functions to protect against foreign invaders, becomes hyperactive, forming antibodies that attack normal tissues and organs, including the skin, joints, kidneys, brain, heart, lungs, and blood. Lupus is characterized by periods of illness, called flares, and periods of wellness or remission. Because its symptoms come and go and mimic those of other diseases, lupus is difficult to diagnose. There is no single laboratory test that can definitively prove that a person has the complex illness. To date, lupus has no known cause or cure. Early detection and treatment are the key to a better health outcome and can usually lessen the progression and severity of the disease. Anti-inflammatory drugs, antimalarials, and steroids (such as cortisone and others) are often used to treat lupus. Cytotoxic chemotherapies, like those used in the treatment of cancer, are also used to suppress the immune system in lupus patients. A new edition of this established and well-regarded reference combines basic science with clinical science to provide a translational medicine model. Systemic Lupus Erythematosus, Sixth Edition, is a useful reference for specialists in the diagnosis and management of patients with SLE, a tool for measurement of clinical activity for pharmaceutical development and basic research of the disease, and a reference work for hospital libraries.

Herbal Bioactive-Based Drug Delivery Systems: Challenges and Opportunities provides a wide-ranging, in-depth resource for herbal bioactives, including detailed discussion of standardization and regulations. The book first explores specific drug delivery systems such as gastrointestinal, ocular, pulmonary, transdermal, and vaginal and rectal. It then discusses novel applications for nano, cosmetics, nutraceuticals, wound healing and cancer treatment. Finally, there is a section focusing on standardization and regulation which includes an enhancement of properties. This book is an essential resource for pharmacologists, pharmaceutical scientists, material scientists, botanists, and all those interested in natural products and drug delivery systems developments.

The book is an introduction to nanomedicine informed by a philosophical reflection about the domain and recent developments. It is an overview of the field, sketching out the main areas of current investment and research. The authors present some case-studies illustrating the different areas of research (nanopharmacy, theranostics and patient monitoring) as well as reflecting on the risks that accompany it, such as unanticipated impacts on human health and environmental toxicity. This introduction to a fast-growing field in modern medical research is of great interest to researchers working in many disciplines as well as the general public. In addition to an overview of the work currently ongoing, the authors critically assess these projects from an ethical and philosophical perspective. Key Features Provides an overview of nanomedicine Employs a reflective and coherent critical evaluation of the benefits and risks of nanomedicine Written in an accessible manner intended for a wide audience Related Titles Hehenberger, M. Nanomedicine: Science, Business, and impact (ISBN 978-9-8146-1376-7). Beg, S., et al. Nanomedicine for the treatment of Disease: From Concept to Application (ISBN 978-1-7746-3443-1) Brenner, S. The Clinical Nanomedicine Handbook (ISBN 978-1-1380-7578-8)

The book is an introduction to nanomedicine informed by a philosophical reflection about the domain and recent developments. It is an overview of the field, sketching out the main areas of current investment and research. The authors present some case-studies illustrating the different areas of research (nanopharmacy, theranostics and patient monitoring) as well as reflecting on the risks that accompany it, such as unanticipated impacts on human health and environmental toxicity. This introduction to a fast-growing field in modern medical research is of great interest to researchers working in many disciplines as well as the general public. In addition to an overview of the work currently ongoing, the authors critically assess these projects from an ethical and philosophical perspective. Key Features Provides an overview of nanomedicine Employs a reflective and coherent critical evaluation of the benefits and risks of nanomedicine Written in an accessible manner intended for a wide audience Related Titles Hehenberger, M. Nanomedicine: Science, Business, and impact (ISBN 978-9-8146-1376-7). Beg, S., et al. Nanomedicine for the treatment of Disease: From Concept to Application (ISBN 978-1-7746-3443-1) Brenner, S. The Clinical Nanomedicine Handbook (ISBN 978-1-1380-7578-8)

Topical and transdermal drug delivery systems (TDDs) have several advantages over traditional drug delivery methods, as they can be less invasive, more sanitary, more cost-effective, and may result in better patient compliance. TDDs play a significant role in therapeutics with a variety of preparations and approaches designed by expert formulation scientists. This volume integrates a wide variety of case studies, research, and theories to reveal their diversity and capture the novel approaches of transdermal and topical drug delivery employed by developers and content experts in the field. It provides an abundance of important information and state-of-the-art research on topical and transdermal drug delivery systems and addresses the basics of drug delivery systems, strategies to enhance permeation across membranes, and formulation and evaluation of diverse dosage forms. The volume presents an evaluation of the pros and cons of conventional drug delivery systems against TDDs and discusses the nuances of micro- and nano-systems in TDDs. The extraordinary packages of nano systems (vesicular systems, polymeric nanoparticles, nanoemulsion and dendrimers) are broadly discussed, and their applications are reviewed through a transdermal route. The book looks at TDDs and the main nanoparticles used in skin diseases and lesions of the aging, such as psoriasis, vitiligo, cancer, lesions of the aging and others. Chapters also discuss polymeric micelles in topical and transdermal delivery; microneedles; emulsion, nanoemulsion and microemulsion; TDDs in pulmonary drug delivery systems; nanoencapsulated nasal drug delivery systems; skin sensitivity and irritation testing for transposing transdermal drug delivery systems; and regulatory aspects of drug development for dermal products. Topical and Transdermal Drug Delivery Systems: Applications and Prospects will be a valuable resource for pharmaceutical scientists and researchers, industry professionals, and academicians and students of the pharmaceutical and biomedical sciences.