Oxetane Synthesis rings play an important role as versatile motifs
both in the overall formation of natural products and in synthetic
organic chemistry. Oxetanes are important motifs in pharmaceutical
chemistry that can confer improved metabolic and physicochemical
properties. These developments continue to enhance the use of
oxetanes in medicinal chemistry. Thanks to the growing commercial
accessibility of oxetane possessing building blocks, together with
improved approaches for the formation, oxetanes are likely to be
progressively utilized in medicinal chemistry programs. Oxetanes
are becoming valuable as a result of their vast diversity of uses
in medicinal chemistry and varying applications. Several procedures
have been developed for the formation and ring-opening of oxetanes
to give important compounds in agrochemical, medicinal and material
sciences. Novel approaches have been developed for the synthesis of
oxetanes. These methods depend on both established synthetic
approaches and development of many novel approaches for the
formation of oxetanes.
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