Psychiatric Pharmacogenomics is a book written to help clinicians
to use pharmacogenomic testing to improve the pharmacotherapy that
they provide for their patients. It is designed to teach clinicians
how to order pharmacogenomic tests and interpret the results.
Clinical examples are used to underscore the specific indications
for pharmacogenomic testing and to clarify the clinical usefulness
of identifying atypical genotypes that result in problematic
responses to medication.
The first section of the book begins with a basic review of
molecular genetics. Additionally, the book also includes an
extensive glossary of technical terms associated with molecular
genetics and pharmacogenomics. The clinical utility of
pharmacogenomic testing is demonstrated throughout the book by
describing the implications of genetic variations for the care of
individual patients.
The second section of the book is organized into fourteen chapters
that each focus on the clinical implications of testing for
specific genes for which variants have been associated with either
therapeutic response or side effects of psychotropic medications.
Each of these chapters is structured in the same manner and
involves a description of the gene and its significant variants.
Each chapter also includes one or more clinical vignettes.
The third section of the book discusses the clinical usefulness of
pharmacogenomic testing, ethical issues associated with
pharmacogenomic testing, and provides predictions for the future
development of more sophisticated pharmacogenomic testing.
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