Books > Medicine > Clinical & internal medicine > Cardiovascular medicine
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Atherosclerosis: Diet and Drugs (Paperback, 2005 ed.)
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Atherosclerosis: Diet and Drugs (Paperback, 2005 ed.)
Series: Handbook of Experimental Pharmacology, 170
Expected to ship within 10 - 15 working days
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Cardiovascular diseases continue to be the leading cause of death
in the - jority of industrialized countries. The most frequent
underlying pathology, namely atherosclerosis, and its clinical
sequelae, namely coronary heart d- ease, cerebrovascular disease
and peripheral artery disease, remain common although for a long
time we have been made aware of avoidable or mo- ?able etiological
factors such as smoking, fat-rich diet or lack of exercise, and
although these adverse lifestyle factors have been extensively
addressed by population-wide primary prevention programs.
Cardiovascular morbidity and mortality also remain high despite
successful anti-hypertensive and lipid lowering drug therapies
which help to reduce cardiovascular morbidity and mortality by
about 30% in both secondary and tertiary prevention settings. This
can partly be explained by the increasing life expectancy and
growing p- portionofelderly
people,especiallyinEuropeandNorthAmerica. Inaddition, the World
Health Organization makes the alarming prediction that probably in
response to the spreading of western dietary behavior and lack of
exercise resulting in an increasing prevalence of diabetes,
dyslipidemia and hypert- sion, cardiovascular diseases rather than
infectious diseases will become the most frequent cause of death
worldwide. This volume of the Handbook of Experimental Pharmacology
entitled "Atherosclerosis" is divided into four parts and intends
to give an overview on the pathogenesis of atherosclerosis,
established treatment and prevention regimen, and of perspectives
for the development of new treatment modalities.
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