Experts address the role of neuromodulators and opiate receptors in
alcohol and drug dependence. They present innovative research
techniques, new discoveries, and possible clinical correlates that
allow for a much greater understanding of the clinical phenomena
surrounding alcohol and narcotic use. Included in this
thought-provoking volume are a comprehensive review of the current
knowledge of the endogenous opiates, their interactions with the
opiate receptors, and the potential relationship that these
substances might have in promoting the development of dependence,
tolerance, and withdrawal; the translation of the basic physiologic
findings occuring during withdrawal to treatment of withdrawal
symptoms in the clinical setting; and a physiological explanation
for the rationale of using clonidine and naltrexone to accelaerate
the detoxification process without undue discomfort.
General
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